Search results for "Enos"

showing 10 items of 1576 documents

Stenosi del giunto pielo-ureterale unilaterale congenita: identificazione di biomarcatori, valutazione clinico-strumentale del danno renale e correla…

2015

Stenosi del giunto pielo-ureterale, biomarcatori urinari, fibrosi, funzione renale, matrice extracellulare.

Stenosi del giunto pielo-ureterale biomarcatori urinari fibrosi funzione renale matrice extracellulare.
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Stenosi del giunto pielo-ureterale unilaterale: valutazione del danno renale correlando il dati clinico strumentale con quello istologico ed immunois…

2008

Stenosi giunto pielo ureterale bambinoSettore MED/20 - Chirurgia Pediatrica E Infantile
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Starting Easy: FFR in a High-Grade Stenosis

2016

A simple representative case of FFR in a high-grade stenosis. The gradient is confirmed by pushing the sensor forward. Equalization is confirmed at the end of the procedure.

StenosisComputer scienceSimple (abstract algebra)Equalization (audio)medicinemedicine.diseaseAlgorithm
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Structure elucidation of the adducts formed by fjord region Dibenzo[a,l]pyrene-11,12-dihydrodiol 13,14-epoxides with deoxyguanosine.

1999

Model adducts to be used in the identification of biologically formed adducts were synthesized by reaction of fjord-region dibenzo[a,l]pyrene 11,12-dihydrodiol 13,14-epoxides (DB[a,l]PDE) and deoxyadenosine (dA). The (+/-)-anti-DB[a,l]PDE was reacted with dA in dimethylformamide at 100 degrees C for 30 min to give four DB[a, l]PDE-14-N(6)dA adducts: (-)-anti-trans (26%), (+)-anti-trans (26%), (-)-anti-cis (17%), and (+)-anti-cis (17%). The (+/-)-syn-DB[a,l]PDE was reacted with dA under the same conditions to yield four DB[a, l]PDE-14-N(6)dA adducts and one N7Ade adduct: (+)-syn-cis (19%), (+)-syn-trans (13%), (-)-syn-cis (19%), (-)-syn-trans (13%), and (+/-)-syn-DB[a,l]PDE-14-N7Ade (22%). T…

Steric effectsCircular dichroismMagnetic Resonance SpectroscopyMolecular StructureStereochemistryDeoxyguanosineGeneral MedicineDNAFast atom bombardmentToxicologyMass SpectrometryAdductDihydroxydihydrobenzopyreneschemistry.chemical_compoundDNA AdductsStructure-Activity RelationshipSpectrometry FluorescenceDeoxyadenosinechemistryDimethylformamidePyreneStereoselectivityChromatography High Pressure LiquidChemical research in toxicology
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Synthesis of oligodeoxynucleotides containing diastereomeric dihydrodiol epoxide-N6-deoxyadenosine adducts of polycyclic aromatic hydrocarbons

1993

Abstract A generally applicable route is reported for the synthesis of oligodeoxynucleotides which contain structurally defined N 6 -deoxyadenosine adducts, derived from sterically highly hindered dihydrodiol epoxides of polycyclic aromatic hydrocarbons (PAH).

Steric effectsOligonucleotideStereochemistryOrganic ChemistryDiastereomerEpoxideBiochemistryAdductDeoxyribonucleosidechemistry.chemical_compoundDeoxyribonucleotidechemistryDeoxyadenosineDrug DiscoveryOrganic chemistryTetrahedron Letters
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ChemInform Abstract: Synthesis of Oligodeoxynucleotides Containing Diastereomeric Dihydrodiol Epoxide-N6-Deoxyadenosine Adducts of Polycyclic Aromati…

2010

Abstract A generally applicable route is reported for the synthesis of oligodeoxynucleotides which contain structurally defined N 6 -deoxyadenosine adducts, derived from sterically highly hindered dihydrodiol epoxides of polycyclic aromatic hydrocarbons (PAH).

Steric effectschemistry.chemical_compoundDeoxyadenosineStereochemistryChemistryDiastereomerNucleic acidEpoxideGeneral MedicineAdductChemInform
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REGULATORY ELEMENTS OF THE LEUKAEMIA INHIBITORY FACTOR (LIF) PROMOTER IN MURINE BONE MARROW STROMAL CELLS

1999

Leukaemia inhibitory factor (LIF) plays an important role as a haematopoietically active cytokine. As described earlier in a murine model, interleukin 1 (IL-1) induced LIF mRNA and protein expression. We utilized the murine cell line +/+-1.LDA11 to further define regulatory mechanisms of LIF expression in bone marrow stromal cells. The production of LIF mRNA is stimulated by IL-1beta, TNF-alpha, and the cAMP analogue 8-bromoadenosine 3':5'-monophosphate (8BrcAMP). LIF mRNA expression is controlled at the transcriptional level. Different fragments from -542 to -45 bp 5' upstream of the transcriptional start site of the murine LIF gene were fused to the luciferase gene. All LIF-promoter lucif…

Stromal cellRecombinant Fusion Proteinsmedicine.medical_treatmentImmunology8-Bromo Cyclic Adenosine MonophosphateBone Marrow CellsStimulationRegulatory Sequences Nucleic AcidBiologyLeukemia Inhibitory FactorBiochemistryMiceGenes ReportermedicineAnimalsHumansImmunology and AllergyLuciferaseRNA MessengerNuclear proteinPromoter Regions GeneticMolecular BiologyCells CulturedLymphokinesMessenger RNAInterleukin-6Tumor Necrosis Factor-alphaInterleukinHematologyMolecular biologyGrowth InhibitorsRecombinant ProteinsCytokinemedicine.anatomical_structureGene Expression RegulationBone marrowStromal CellsInterleukin-1Cytokine
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Incorporation of ATP synthetase into long-term stable liposomes of a polymerizable synthetic sulfolipid

1981

SulfolipidPolymersUltraviolet RaysLipid BilayersBiophysicsRhodospirillum rubrumModels BiologicalBiochemistrychemistry.chemical_compoundMultienzyme ComplexesStructural BiologyGeneticsFreeze FracturingMolecular BiologyLiposomeATP synthasebiologyChemistryPhosphotransferasesCell BiologySulfuric AcidsLipidsATP Synthetase ComplexesAdenosine DiphosphateEnzyme ActivationMicroscopy ElectronBiochemistryLiposomesbiology.proteinFEBS Letters
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Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs

2004

Ischemia-reperfusion injury, a clinical problem during cardiac surgery, involves worsened adenosine trisphosphate (ATP) generation and damage to the heart. We studied carbon monoxide ( CO) pretreatment, proven valuable in rodents but not previously tested in large animals, for its effects on pig hearts subjected to cardiopulmonary bypass with cardioplegic arrest. Hearts of CO-treated pigs showed significantly higher ATP and phosphocreatine levels, less interstitial edema, and apoptosis of cardiomyocytes and required fewer defibrillations after bypass. We conclude that treatment with CO improves the energy status, prevents edema formation and apoptosis, and facilitates recovery in a clinical…

Sus scrofaMyocardial IschemiaApoptosisCardiotonic AgentsBiochemistrylaw.inventionchemistry.chemical_compoundAdenosine Triphosphateischemia reperfusion; heart arrest; apoptosis; hypoxia; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apoptosis; Carbon Monoxide; Cardiotonic Agents; Edema; Electric Countershock; Energy Metabolism; Female; Guanosine Triphosphate; Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes Cardiac; NAD; NADP; Oxidation-Reduction; Sus scrofa; Cardiopulmonary BypasslawEdemaEdemaMyocytes CardiacCarbon MonoxideCardiopulmonary BypassMED/04 - PATOLOGIA GENERALEHeartCardiac surgeryAdenosine DiphosphateAnesthesiaCardiologyFemaleGuanosine Triphosphatemedicine.symptomCardiacOxidation-ReductionBiotechnologymedicine.drugischemia reperfusion; heart arrest; apoptosis; hypoxiaAdenosine monophosphatemedicine.medical_specialtyCardiotonic AgentsElectric CountershockMyocardial Reperfusion InjuryPhosphocreatineInternal medicineGeneticsmedicineCardiopulmonary bypassischemia reperfusionAnimalsMolecular BiologyMyocytesbusiness.industryhypoxiaNADAdenosineapoptosiAdenosine MonophosphateAdenosine diphosphatechemistryEnergy MetabolismbusinessNADPheart arrest
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Long Term Outcome after Application of the Angio-Seal Vascular Closure Device in Minipigs

2016

PLoS one 11(9), e0163878 (2016). doi:10.1371/journal.pone.0163878

SwineAnticoagulant Therapylcsh:MedicineFemoral artery030204 cardiovascular system & hematologyPathology and Laboratory Medicine030218 nuclear medicine & medical imagingWhite Blood Cells0302 clinical medicinePig ModelsAnimal CellsMedicine and Health SciencesVascular closure deviceLymphocyteslcsh:ScienceComputed tomography angiographyMammalsStenosisMultidisciplinarymedicine.diagnostic_testPharmaceuticsAgricultureArteriesAnimal ModelsClopidogrelCardiovascular Therapymedicine.anatomical_structureVertebratesAnatomyCellular TypesArterymedicine.drugResearch Articlemedicine.medical_specialtyLivestockImmune CellsAnimal TypesImmunologyLumen (anatomy)Research and Analysis Methods03 medical and health sciencesSigns and SymptomsModel OrganismsDrug TherapyDiagnostic Medicinemedicine.arterymedicineAnimalsDomestic AnimalsBlood Cellsbusiness.industrylcsh:ROrganismsBiology and Life SciencesCell BiologyFemoral ArteriesInternal elastic laminamedicine.diseaseSurgeryStenosisAmniotesCardiovascular AnatomyBlood Vesselslcsh:QbusinessZoologyPLoS ONE
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