Search results for "Enrichment"

Using Digital Resources for Content and Language Integrated Learning: A Proposal for the ICT-Enrichment of a Course on Biology and Geology

2019

Hoy en día se utiliza una gran variedad de herramientas digitales para apoyar la enseñanza y el aprendizaje de lenguas. Sus potenciales efectos positivos en el proceso de aprendizaje pueden ser particularmente útiles para abordar los retos que surgen en enfoques como el Aprendizaje Integrado de Contenidos y Lenguas Extranjeras (AICLE), donde se espera que los estudiantes consigan dominar no solo el contenido de la asignatura, sino también la lengua extranjera que se utiliza como medio de comunicación. Este artículo tiene como objetivo ofrecer una propuesta de enriquecimiento digital de cursos AICLE, la cual ha sido implementada en una asignatura de Biología y Geología en inglés impartida en…

Binding of RNA Aptamers to Membrane Lipid Rafts: Implications for Exosomal miRNAs Transfer from Cancer to Immune Cells

2020

Intraluminal vesicles (ILVs) are released into the extracellular space as exosomes after the fusion of multivesicular bodies (MVBs) with the plasma membrane. miRNAs are delivered to the raft-like region of MVB by RNA-binding proteins (RBPs). RNA loading into exosomes can be either through direct interaction between RNA and the raft-like region of the MVB membrane, or through interaction between an RBP&ndash

Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies

2019

The distribution of amyloid beta peptide 42 (Aβ42) between model exosomal membranes and a buffer solution was measured. The model membranes contained liquid-ordered regions or phosphatidylserine. Results demonstrated that up to ca. 20% of amyloid peptide, generated in the plasma (or intracellular) membrane as a result of proteolytic cleavage of amyloid precursor proteins by β- and γ-secretases, can stay within the membrane milieu. The selection of RNA aptamers that bind to Aβ42 incorporated into phosphatidylserine-containing liposomal membranes was performed using the selection-amplification (SELEX) method. After eight selection cycles, the pool of RNA aptamers was isol…

Liquid membranes as a sample preparation method in environmental analysis

2014

Because of the complexity of environmental matrices, there is a great need of application efficient sample preparation procedures for environmental analysis. One of such possibilities is using, during sample-pretreatment step, the membrane extraction (ME) methods. They include, for instance, a three-phase extraction system named supported liquid membranes that has been used in recent years many times for isolation and preconcentration of various analytes from complex sample matrices. The examples of application the commonly used types of SLMs, hollow fiber supported liquid membrane and flat sheet supported liquid membrane, are listed and described. Additionally, the area of membrane extract…

“Developing Capabilities”. Inclusive Extracurricular Enrichment Programs to Improve the Well-Being of Gifted Adolescents

2021

The educational inclusion of gifted students requires not only equity but also emotional accessibility and social participation. However, different studies indicate that gifted students constitute a vulnerable group (for example, the incidence of bullying is higher). Psychosocial variables are determinants for the development and expression of giftedness, particularly during adolescence. This study analyzes the impact of an inclusive extracurricular enrichment program for gifted secondary school students on the well-being of adolescents. The program was based on the enrichment model of Renzulli and Reis (2016). The objective was to develop a cluster to facilitate high-achieving learning in …

A dynamic multiple receptor conformations (MD-MRC) approach to enhance early enrichment in virtual screening. A case study on PPAR-alpha

2016

Environmental Enrichment During Adolescence Mitigates Cognitive Deficits and Alcohol Vulnerability due to Continuous and Intermittent Perinatal Alcoh…

2020

Perinatal alcohol exposure affects ontogenic neurodevelopment, causing physical and functional long-term abnormalities with limited treatment options. This study investigated long-term consequences of continuous and intermittent maternal alcohol drinking on behavioral readouts of cognitive function and alcohol vulnerability in the offspring. The effects of environmental enrichment (EE) during adolescence were also evaluated. Female rats underwent continuous alcohol drinking (CAD)—or intermittent alcohol drinking paradigm (IAD), along pregestation, gestation, and lactation periods—equivalent to the whole gestational period in humans. Male offspring were reared in standard conditions or EE un…

Sediment delivery processes and chemical transport in a small forested basin

2005

Recent reaserch has directed attention to the properties of the eroded material because of its influence in deposition phenomena and in carrying capacity of pollutant materials

The adaptations to tube-dwelling life of Propsilocerus akamusi (Diptera: Chironomidae) larvae and its eutrophication-tolerant mechanisms

2019

Propsilocerus akamusi (Diptera: Chironomidae) is a dominant macroinvertebrate species in many eutrophic lakes in subtropical and temperate zones. P. akamusi larvae can migrate deep into the sediment (>30 cm) during summer where is no oxygen. However, to our knowledge, the specific adaptive tactics of its tube-dwelling life (>30 cm) and underlying mechanisms why this species is favored by nutrient-rich lakes remain limited. With the understanding above-mentioned issues, we can provide important information for the development of sensitive biomonitoring. We examined monthly morphological dynamics and physiological adaptations of P. akamusi to anoxic conditions, and environmental relationships…

Vidējā pirmsskolas vecuma bērnu vārdu krājuma bagātināšana

2019

Liene Brokāne. Kvalifikācijas darba tēma „Vidējā pirmsskolas vecuma bērnu vārdu krājuma bagātināšana”. Pētījumā noskaidrots, kā bērns apgūst valodu, papildinot savu vārdu krājumu ar jauniegūtiem vārdiem, kas bērnam individuālā vārdu krājuma attīstībā ir nozīmīgi. Pētījuma mērķis: Teorētiski izpētīt un praktiski pārbaudīt vidējās pirmsskolas vecuma bērnu vārdu krājuma bagātināšanu pedagoģiskajā procesā. Kvalifikācijas darbs sastāv no divām nodaļām: 1.Pedagoģijas un psiholoģijas zinātnieku atziņas par vidējā pirmsskolas vecuma bērnu vārdu krājumu. 2.Vidējā pirmsskolas vecuma bērnu vārdu krājuma bagātināšana dabas vidē. Teorētiskajā daļā analizētas pedagoģijas un psiholoģijas zinātnieku atziņa…