Search results for "Estudio"

showing 10 items of 791 documents

Dietary intake in population with metabolic syndrome: is the prevalence of inadequate intake influenced by geographical area? cross-sectional analysi…

2018

Inadequate diet influences chronic diseases such as cardiovascular disease (CVD), the leading cause of death in Spain. CVD figures vary from one geographical region to another

0301 basic medicineMaleSíndrome metabòlicacumplimiento del pacienteCross-sectional studyhumanosejercicio físicoOverweightDiet MediterraneanRecommended Dietary AllowancesgeografíaNutrientClinical trialsSurveys and QuestionnairesFood choicePrevalenceMedicineMicronutrientsmediana edadDietoteràpiaRandomized Controlled Trials as Topic2. Zero hungereducation.field_of_studyancianoNutrition and DieteticssobrepesoGeographydietaensayos clínicos controlados aleatorizados como asuntoprevalenciaPREDIMED-Plus studyMiddle AgedMetabolic syndrome3. Good healthestado nutricionalDietary Reference IntakePlace of residenceFemalemedicine.symptomevaluación nutricionalcantidad dietética recomendadageographical arealcsh:Nutrition. Foods and food supplynutrient adequacyPopulationNutritional Statuslcsh:TX341-641metabolic syndromeArticle03 medical and health sciencesEnvironmental healthHumansplace of residencecardiovascular diseasesObesityeducationobesidadExerciseAgedGeographical area030109 nutrition & dieteticsNutrient adequacybusiness.industryDietary intakeDiet therapymicronutrientesOverweightmedicine.diseaseObesityDietCross-Sectional StudiesNutrition AssessmentSpainPatient ComplianceMetabolic syndromebusinessdietary intakeFood ScienceAssaigs clínicsestudios transversales
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Dietary Diversity and Nutritional Adequacy among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Plus Study: A Cross-Sectional An…

2019

Dietary guidelines emphasize the importance of a varied diet to provide an adequate nutrient intake. However, an older age is often associated with consumption of monotonous diets that can be nutritionally inadequate, increasing the risk for the development or progression of diet-related chronic diseases, such as metabolic syndrome (MetS). To assess the association between dietary diversity (DD) and nutrient intake adequacy and to identify demographic variables associated with DD, we cross-sectionally analyzed baseline data from the PREDIMED-Plus trial: 6587 Spanish adults aged 55&ndash

0301 basic medicineMaleSíndrome metabòlicamodelos logísticosCross-sectional studydietary diversityhumanosOverweightRecommended Dietary AllowancesFood groupencuestas sobre dietas0302 clinical medicineMedicinemediana edad2. Zero hungereducation.field_of_studyancianoNutrition and DieteticsdietaPREDIMED-Plus studyMiddle Aged3. Good healthestado nutricionalnutritionQuartileAvaluació de l'estat nutricionalDietary Reference IntakeDietaFemalemedicine.symptomNutritional status measurementcantidad dietética recomendadalcsh:Nutrition. Foods and food supplynutrient adequacyPopulationNutritional Status030209 endocrinology & metabolismlcsh:TX341-641Diet SurveysArticlemetabolic syndrome03 medical and health sciencesPremides-plus studyEnvironmental healthPREDIMED-Plus study aging dietary diversity metabolic syndrome nutrient adequacyHumansObesityanálisis multifactorialeducationobesidadAged030109 nutrition & dieteticsbusiness.industryagingOdds ratiomedicine.diseaseObesityDietCross-Sectional StudiesLogistic ModelsMultivariate AnalysisbusinessFood Scienceestudios transversales
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Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study.

2017

Background-The relationship between plasma concentrations of betaine and choline metabolism and major cardiovascular disease (CVD) end points remains unclear. We have evaluated the association between metabolites from the choline pathway and risk of incident CVD and the potential modifying effect of Mediterranean diet interventions. Methods and Results-We designed a case-cohort study nested within the PREDIMED (Prevention With Mediterranean Diet) trial, including 229 incident CVD cases and 751 randomly selected participants at baseline, followed up for 4.8 years. We used liquid chromatography-tandem mass spectrometry to measure, at baseline and at 1 year of follow-up, plasma concentrations …

0301 basic medicineMaleTime FactorsMediterranean dietEpidemiologymodelos de riesgos proporcionaleshumanosSistema cardiovascular -- Malaltieséteres de fosfolípidosDisease030204 cardiovascular system & hematologyGut floraDiet MediterraneanCholinechemistry.chemical_compound0302 clinical medicineBetainecardiovascular diseaseRisk FactorsTandem Mass Spectrometryestudios prospectivosmetabolómicaCholineProspective StudiesTrimethylamine-n-oxidemediana edadOriginal ResearchDiet and Nutritionmetilaminas2. Zero hungerAged 80 and overChromatographyancianoCholine metabolismbiologydietaresultado del tratamientoIncidencePhospholipid Ethersdistribución de la ji al cuadradoMiddle AgedCardiovascular disease3. Good healthPrimary PreventioncolinaTreatment OutcomeCardiovascular Diseasesespectrometría de masas en tándemPlasma concentrationProfileFemaleCardiology and Cardiovascular Medicinefosforilcolinamedicine.medical_specialtyPhosphorylcholineestudios de casos y controlesenfermedades cardiovascularesGut microbiotaincidencia03 medical and health sciencesMethylaminesfactores de tiempoInternal medicineMediterranean dietOxidationmedicinefactores de riesgoHumansMetabolomicsanálisis multifactorialDieta -- Mediterrània Regió de lacromatografíaAgedProportional Hazards ModelsChi-Square Distributiongut microbiotabusiness.industrybetaínaPlasma sanguiniLifestylebiology.organism_classificationPredimedDietBetainePhosphatidylcholine030104 developmental biologyEndocrinologychemistrySpainCase-Control StudiesMultivariate AnalysisbusinessBiomarkersChromatography Liquid
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Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial.

2018

Background: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (&omega

0301 basic medicineMaleeicosapentaenoic acidmodelos logísticoshumanosdepresiónencuestas sobre dietas0302 clinical medicineClinical trialsSurveys and QuestionnairesOdds RatioPrevalence030212 general & internal medicineDepressió psíquicamediana edadDietoteràpia2. Zero hungerancianoNutrition and Dieteticsintegumentary systemdietaDepressionEuropean researchFatty AcidsprevalenciaFishesfood and beveragesMiddle Ageddocosahexaenoic acidcociente de probabilidades relativasMental depressiondepressionChristian ministryFemaleomega-3lcsh:Nutrition. Foods and food supplyEuropean Regional Development Fundlcsh:TX341-641Àcids grassos omega-3Diet SurveysArticle03 medical and health sciencesalimentos del marDepression (economics)pecestrastorno depresivoEnvironmental healthPolitical scienceFatty Acids Omega-3ingesta energéticaOmega-3 fatty acidsAnimalsHumansácidos grasosAgedConsumption (economics)fishconducta alimentariaDepressive Disorder030109 nutrition & dieteticsDiet therapyLife timeFeeding BehaviorPredimedDietCross-Sectional StudiesLogistic ModelsSeafoodanimalesEnergy IntakeFood Scienceestudios transversalesAssaigs clínicsNutrients
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Análisis bibliométrico de la producción científica española en Enfermedades Infecciosas y en Microbiología.

2016

Resumen Introduccion El analisis bibliometrico de la produccion y repercusion de los documentos por areas de conocimiento es un indicador cuantitativo y cualitativo de la actividad investigadora realizada en ese campo. El objetivo de este articulo es conocer la contribucion de las instituciones espanolas a la investigacion en Enfermedades Infecciosas y en Microbiologia en los ultimos anos. Material y metodos Se analizaron los documentos publicados en las revistas incluidas en las categorias «Infectious Diseases» y «Microbiology» de la Web of Science (Science Citation Index Expanded) de la ISI Web of Knowledge desde el ano 2000 al 2013. Resultados En Enfermedades Infecciosas, Espana ocupo la…

0301 basic medicineMicrobiology (medical)03 medical and health sciences0302 clinical medicine030106 microbiology030212 general & internal medicineBibliometric analysis Enfermedades infecciosas España Estudio bibliométrico Infectious diseases Microbiology Microbiología Producción científica Scientific production Spain
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Detection of MET Alterations Using Cell Free DNA and Circulating Tumor Cells from Cancer Patients

2020

MET alterations may provide a potential biomarker to evaluate patients who will benefit from treatment with MET inhibitors. Therefore, the purpose of the present study is to investigate the utility of a liquid biopsy-based strategy to assess MET alterations in cancer patients. We analyzed MET amplification in circulating free DNA (cfDNA) from 174 patients with cancer and 49 healthy controls and demonstrated the accuracy of the analysis to detect its alteration in patients. Importantly, a significant correlation between cfDNA concentration and MET copy number (CN) in cancer patients (r = 0.57, p &lt

0301 basic medicineOncologyMale<i>MET</i> copy numbermedicine.medical_treatmentproteínas protooncogénicas c-metdosificación génicahumanosresistencia a medicamentosDrug ResistanceGene Dosagecirculating free DNA (cfDNA)<i>MET</i> amplificationTargeted therapyTargeted therapy0302 clinical medicineCirculating tumor cellestudios prospectivosNeoplasmsantineoplásicosProspective Studieslcsh:QH301-705.5Circulating tumor cells (CTCs)neoplasiasGeneral MedicineProto-Oncogene Proteins c-mettargeted therapyNeoplastic Cells CirculatingErbB ReceptorsCell-free fetal DNA030220 oncology & carcinogenesisinhibidores de proteína cinasasBiomarker (medicine)FemaleMET protein expressionCell-Free Nucleic AcidsMET amplificationmedicine.medical_specialtycirculating tumor cells (CTCs)estudios de casos y controlesMet amplificationCirculating free DNA (cfDNA)Antineoplastic AgentsArticle03 medical and health sciencesInternal medicinemedicineBiomarkers TumorHumansLiquid biopsyProtein Kinase InhibitorsRetrospective Studiesbusiness.industryHead and neck cancerestudios retrospectivosLiquid BiopsyCancermedicine.disease030104 developmental biologylcsh:Biology (General)Drug Resistance NeoplasmCase-Control StudiesMET copy numberbusinessCells
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Plasma Metabolites Associated with Coffee Consumption: A Metabolomic Approach within the PREDIMED Study

2019

Few studies have examined the association of a wide range of metabolites with total and subtypes of coffee consumption. The aim of this study was to investigate associations of plasma metabolites with total, caffeinated, and decaffeinated coffee consumption. We also assessed the ability of metabolites to discriminate between coffee consumption categories. This is a cross-sectional analysis of 1664 participants from the PREDIMED study. Metabolites were semiquantitatively profiled using a multiplatform approach. Consumption of total coffee, caffeinated coffee and decaffeinated coffee was assessed by using a validated food frequency questionnaire. We assessed associations between 387 metabolit…

0301 basic medicinePREDIMEDMalehumanosestudios de casos y controlescoffeeLibrary sciencelcsh:TX341-641030209 endocrinology & metabolismCoffee consumptionCoffeeArticleCohort Studies03 medical and health sciencesPlasma0302 clinical medicineCoffeescafeínaPolitical scienceCaffeinemetabolómicaHumansMetabolomicsestudios de cohortesmediana edadplasmaAgedanciano030109 nutrition & dieteticsNutrition and DieteticscaféMiddle AgedPredimedPredimedmetabolomicsCross-Sectional StudiesCase-Control StudiesChristian ministryFemalelcsh:Nutrition. Foods and food supplyestudios transversalesFood Science
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Measuring stress in clinical and nonclinical subjects using a German adaptation of the Perceived Stress Scale

2020

ANTECEDENTES/OBJETIVO: El estrés se percibe de manera diferente entre los individuos, lo que podría ser particularmente cierto para los sujetos no clínicos y clínicos. Por esta razón, probamos una adaptación alemana de la Perceived Stress Scale de 10 ítems (PSS-10) para el ajuste del modelo y la invarianza de la medición en una gran muestra clínica y no clínica. MÉTODO: Realizamos (1) un análisis factorial confirmatorio múltiple (CFA) en 1.248 sujetos no clínicos y 575 pacientes ambulatorios, (2) invarianza de medición con CFA multigrupo, (3) correlaciones con constructos relevantes y (4) cálculos de la consistencia interna para la escala general y las subescalas Desvalidez y Autoeficacia. …

050103 clinical psychologyOriginal articlePerceived Stress Scale050109 social psychologyLearned helplessnessAdaptation (eye)Análisis FactorialGermanClinical subjectsStress (linguistics)0501 psychology and cognitive sciencesMeasurement invarianceInvarianzaInstrumental study.05 social sciencesInvariancePerceived Stress ScalePacientes ; Instrumental study ; Invariance ; Clinical subjects ; Invarianza ; Estudio instrumental ; Factor analyses ; Perceived Stress Scale ; Análisis FactorialMental healthlanguage.human_languageConfirmatory factor analysisClinical PsychologyEstudio instrumental.languageFactor analysesPacientesPsychologyClinical psychologyInternational Journal of Clinical and Health Psychology : IJCHP
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The cross-cultural and transdiagnostic nature of unwanted mental intrusions

2019

Unwanted mental intrusions (UMIs), typically discussed in relation to Obsessive-Compulsive Disorder (OCD), are highly prevalent, regardless of the specific nationality, religion, and/or cultural context. Studies have also shown that UMIs related to Body Dysmorphic Disorder (BDD), Illness anxiety/Hypochondriasis (IA-H), and Eating Disorders (EDs) are commonly experienced. However, the influence of culture on these UMIs and their transdiagnostic nature has not been investigated.Participants were 1,473 non-clinical individuals from seven countries in Europe, the Middle-East, and South America. All the subjects completed the Questionnaire of Unpleasant Intrusive Thoughts, which assesses the occ…

050103 clinical psychologyUnwanted mentalCross-sectional studyCultural contextUnwanted mental intrusions050109 social psychologyTransdiagnósticoObsessive-compulsive spectrum disordersmental disordersmedicineCross-cultural0501 psychology and cognitive sciencesCross-cultural studyEstudio transculturalCross-sectional studyTransdiagnosticTrastornos del espectro obsesivo-compulsivo05 social sciencesCross-cultural study; Cross-sectional study; Obsessive-Compulsive spectrum disorders; Transdiagnostic; Unwanted mental intrusions; Clinical Psychologymedicine.diseaseEstudio transversalEating disordersClinical PsychologyOriginals articleObsessive-Compulsive spectrum disordersBody dysmorphic disorderAnxietyIntrusiones mentales no deseadasmedicine.symptomPsychologyClinical psychology
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Functional links of obsessive, dysmorphic, hypochondriac, and eating-disorders related mental intrusions.

2017

Unwanted mental intrusions (UMIs) are the normal variants of obsessions in Obsessive-Compulsive Disorder (OCD), preoccupations about defects in Body Dysmorphic Disorder (BDD), images about illness in Hypochondriasis (HYP), and thoughts about eating in Eating Disorders (EDs). The aim was to examine the similarities and differences in the functional links of four UMI contents, adopting a within-subject perspective.Las intrusiones mentales no deseadas (IM) son la variante normativa de obsesiones en el Trastorno Obsesivo-Compulsivo (TOC), preocupaciones por defectos en el Trastorno Dismórfico Corporal (TDC), imágenes sobre enfermedad en Hipocondría (TH) y pensamientos sobre alimentación en los …

050103 clinical psychologymedicine.medical_specialtyOriginal article03 medical and health sciencesMental intrusions0302 clinical medicineBody dysmorphic disordermedicineObsessive-compulsive disordertrastorno dismórfico corporal0501 psychology and cognitive sciencesIntrusiones mentalesPsychiatryCross-sectional studyTransdiagnostictransdiagnóstico05 social sciencesPerspective (graphical)trastorno obsesivo-compulsivomedicine.disease030227 psychiatryClinical PsychologyEating disordersestudio transversalBody dysmorphic disorderPsychologyInternational journal of clinical and health psychology : IJCHP
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