Search results for "Exam"

Cytokines with Possible Clinical Utility

1987

Biological response modifiers (BRM) are agents aimed at reducing tumor growth, not primarily by exerting direct cytotoxic effects but by modulation of tumor gene expression (e.g., induction of differentiation) or by enhancing host defense mechanisms directed against cancer cells. BRM as primary therapy or as adjuncts to cytotoxic agents in the treatment of cancers have attracted increasing interest in view of stagnating clinical results in many areas [1], and there is increasing evidence of in vitro and in vivo efficacy of these agents. Furthermore, advances in molecular biology suggesting that oncogenes and their products play a crucial role in oncogenesis support approaches to modulation …

The visual query language CQL for transitive and relational computation

2000

Abstract Classification query language (CQL) is a high-level visual query language with a great expressive power. In CQL the processing of ordinary relations and classifications based on transitive relationships is integrated seamlessly. Relations and classifications are represented in the visual interface in a uniform way through relation and classification skeletons. All query formulation in CQL is QBE-like – based on the intuitive way of filling constants and sample values into the skeletons. In order to guarantee great expressive power, relational and classification expressions can be nested freely with each other at unlimited nesting levels. Recursive definition of transitive processin…

Empleo de Socrative para la evaluación del trabajo previo en asignaturas prácticas de laboratorio

2019

[EN] University students of experimental sciences degrees usually go to the laboratory of practices without having prepared the corresponding activity. This fact leads to a poor preparation of them translated into an effective loss of time available for experimentation, and a reduced acquisition of knowledge and skills, among other aspects. In order to solve this problem, in the present communication, the use of on-line questionnaires using the Socrative platform is described to be used as a prior evaluation system to access the laboratory. The results obtained show that the proposed didactic strategy significantly improves the preparation of the students upon arrival to the laboratory, as …

Quaternary and subunit structure of Calliphora arylphorin as deduced from electron microscopy, electrophoresis, and sequence similarities with arthro…

1992

Arylphorin was purified from larvae of the blowfly Calliphora vicina and studied in its oligomeric form and after dissociation at pH 9.6 into native subunits. In accordance with earlier literature, it was electrophoretically shown to be a 500 kDa hexamer (1 x 6) consisting of 78 kDa polypeptides (= subunits). Electron micrographs of negatively stained hexamers show a characteristic curvilinear, equilateral triangle of 12 nm in diameter (top view) and a rectangle measuring 10 x 12 nm (side view). Alternatively, particles in the top view orientation exhibit a roughly circular shape 12 nm in diameter. Crossed immunoelectrophoresis revealed the presence of a major subunit type; the nature of a …

Tear production and intraocular pressure values in clinically normal eyes of whooper swans (<i>Cygnus cygnus</i>)

2018

The objective of this study was to determine the normal range of tear production and values of intraocular pressure (IOP) in clinically normal eyes of whooper swans (Cygnus cygnus). A total of 86 birds: 81 cygnets (6-10 weeks old) and 5 moulting - adult swans (3-6 years old) were examined in this study. Both eyes of all birds underwent a complete ophthalmic examination, including evaluation of tear production with the phenol red thread test (PRTT) and the assessment of the IOP by rebound tonometry, employing the TonoVet® device. The mean ± standard deviation of PRTT values were as follows: all cygnets (81) 22.59±3.48 mm/15s, male cygnets (45) 22.64±3.54 mm/15s, female cygnets (36) 22.53±3.4…

Das Onkozytom der Niere

1988

The angiographic findings in ten patients with renal oncocytoma are described. Characteristic features include: absence of encasement, vascular occlusions, arterio-venous shunts and contrast lakes (8/10). Spoke-wheel arrangement of tumor vessels (8/10). Homogeneous tumour contrast during the capillary phase (7/10). Sharp demarcation from the kidney and surroundings (9/10) and a peritumoral halo (4/10). If the suspicion of an oncocytoma is raised by CT examination of a space-occupying lesion (part I), angiography should be performed to confirm the diagnosis and help in planning surgical treatment.

Diagnosis and therapeutic management of primary headache in an emergency setting

2013

Depth of response to isatuximab, carfilzomib, lenalidomide, and dexamethasone (Isa-KRd) in front-line treatment of high-risk multiple myeloma: Interi…

2020

8508 Background: High-risk (HR) multiple myeloma (MM) still has a significant impaired prognostic outcome. Addition of CD38 monoclonal antibodies to standard-of-care regimens significantly improved response rates and depth of response in newly diagnosed (ND) and relapsed/refractory MM patients (pts). Here, we report the prespecified end of induction interim analysis (IA) of the investigator-initiated GMMG-CONCEPT trial (NCT03104842), evaluating the quadruplet regimen isatuximab plus carfilzomib, lenalidomide and dexamethasone (Isa-KRd) in HR NDMM pts. Methods: 153 pts with HR NDMM are planned to be included into the trial. HR MM is defined by the presence of del17p or t(4;14) or t(14;16) o…

DELL’UTRI E CONTRADA “GEMELLI DIVERSI”: È LA REVISIONE EUROPEA LO STRUMENTO DI OTTEMPERANZA ALLE SENTENZE CEDU

2017

La Cassazione nega l’origine giurisprudenziale del concorso esterno in associazione mafiosa e individua il rimedio della revisione europea per l’attuazione della decisione CEDU nei confronti di soggetti in posizioni simili a quella di Contrada. Il percorso offre l’occasione per riflettere sulla connotazione “oggettiva” della prevedibilità e sull’uguaglianza di trattamento dei condannati. Italian supreme Court denies that the origin of external participation in mafia-type criminal association lies in case law and envisages the European review as the tool to comply with ECtHR judgements in similar cases to that of Contrada. This jurisprudence provides a proper opportunity for an in-depth exam…

A Note on added information in the RAS Procedure: reexamination of some evidence

2006

International audience; An example in Miernyk (1977) presented a rather counterintuitive result, namely that introducing accurate exogenous information into an RAS matrix estimating procedure could lead to an estimate that was worse than one generated by RAS using no exogenous information at all. This became an oft-cited black mark against RAS. Miller and Blair (1985) included a different (and small) illustration of the same possibility. It was recently pointed out by one of us that the Miller/Blair numerical results are wrong. For that reason, we decided to reexamine all the empirical evidence we could find on the subject. While figures in both Miernyk and Miller/Blair appear to be wrong, …