Search results for "Exocrine gland"
showing 9 items of 29 documents
cDNA Cloning and Functional Expression of Jerdostatin, a Novel RTS-disintegrin from Trimeresurus jerdonii and a Specific Antagonist of the α1β1 Integ…
2005
Jerdostatin represents a novel RTS-containing short disintegrin cloned by reverse transcriptase-PCR from the venom gland mRNA of the Chinese Jerdons pit viper Trimeresurus jerdonii. The jerdostatins precursor cDNA contained a 333-bp open reading frame encoding a signal peptide, a pre-peptide, and a 43-amino acid disintegrin domain, whose amino acid sequence displayed 80% identity with that of the KTS-disintegrins obtustatin and viperistatin. The jerdostatin cDNA structure represents the first complete open reading frame of a short disintegrin and points to the emergence of jerdostatin from a short-coding gene. The different residues between jerdostatin and obtustatin/viperistatin are segreg…
Chemistry of pheromonal and defensive secretions in the nymphs and the adults ofDysdercus cingulatus Fabr. (Heteroptera, Pyrrhocoridae)
1991
59 ref.; International audience; The exocrine secretions from the nymphs and the adults of both sexes in D. cingulatus were chemically investigated. Seven compounds were identified in the anterior glands, and eleven in the median dorsoabdominal glands of nymphs and adults of both sexes. Fifty-five compounds were identified in the defensive glands (34 in posterior dorsoabdominal glands ofnymphs and 21 in metathoracic glands of adults), and six in the sternal glandular epithelium of the males. The biological function of the glandular secretions and of their identified compounds were investigated and are discussed.
SAT0378 Autophagy is Up-Regulated in the Salivary Glands of Primary Sjogren's Syndrome Patients and Correlates with the Focus Score and Disease Activ…
2015
Background Autophagy is now considered as a major regulator in trafficking events that activates innate and adaptive immunity and consistent evidence supports its role in autoimmunity (1). Primary Sjogren9s syndrome (pSS) is a systemic autoimmune disease characterized by infiltration of exocrine glands by T and B cells that, producing chemokines and cytokines, coordinate the chronic inflammatory process. No data on the role of autophagy in pSS are available in humans, although studies in mice demonstrated its involvement in the salivary and lacrimal gland homeostasis (2,3). Objectives We investigated the autophagy process in salivary gland tissue and in peripheral T lymphocytes from pSS pat…
Sialotranscriptomics of the argasid tick ornithodoros moubata along the trophogonic cycle
2021
32 páginas, 8 tablas, 6 figuras
Salivary gland proteins alterations in the diabetic milieu
2021
AbstractSalivary glands are considered the chief exocrine glands of the mouth and physiologically contribute to the maintenance of the homeostasis of the oral cavity. They consist of the parotid, submandibular and sublingual glands, which come in pairs and are collectively called the major glands, and the minor glands, which are much smaller and are dispersed throughout the buccal cavity. Salivary glands are distinguished by their size, amount of saliva secretion and their location in the oral cavity. Salivary glands pathophysiology has been a subject of interest in various worldwide metabolic disorders, including diabetes mellitus. Diabetes mellitus (DM), a global health concern, with a pa…
The nasus gland: A new gland in soldiers of Angularitermes (Termitidae, Nasutitermitinae)
2015
Termites have developed many exocrine glands, generally dedicated to defence or communication. Although a few of these glands occur in all termite species, or represent synapomorphies of larger clades, others are morphological innovations of a single species, or a few related species. Here, we describe the nasus gland, a new gland occurring at the base of the nasus of Angularitermes soldiers. The nasus gland is composed of class 1, 2, and 3 secretory cells, a rare combination that is only shared by the sternal and tergal glands of some termites and cockroaches. The ultrastructural observations suggest that the secretion is produced by class 2 and 3 secretory cells, and released mostly by cl…
The effect of two sulphur-containing pesticides, fenitrothion and endosulfan, on glutathione (GSH) content and on GSH S-transferase and gamma-glutamy…
1988
The glutathione (GSH) system of Procambarus clarkii (P.c.), the American red crayfish, is used as a marker of the effects of Fenitrothion (FT) and Endosulfan (ES), organophosphorus and organochlorinated insecticides, respectively. This system has been shown to be sensitive to different heavy metals poisoning, thus it has a double interest as marker for environmental contamination and as a potential source of xenobiotics or their metabolites to humans, since it is being fished commercially. The GSH content of the organ decreased 24 h after treatment with FT. FT promotes a 2-fold induction of GSH S-transferase (GST) activity at 6 h which is followed by a decrease of it at 24 h. The latter coi…
The Harderian Gland of the Djungarian Hamster (<i>Phodopus sungorus</i>): Light- and Electron-Microscopical Investigations
1993
The Harderian gland of the Djungarian hamster Phodopus sungorus was investigated by light and electron microscopy in adult animals of both sexes, held under either long or short photoperiods. These glands have a tubuloalveolar structure. Epithelial cells were seen as small cylindric cells with a large, round nucleus located basally, many small vacuoles distributed throughout the cytoplasm (type I cells) or as rather broad cells with larger vacuoles (type II cells). The ratio of both cell types differed from 1:1 to 2:1 (type I:type II), regardless of the animal’s sex. In the electron microscope, abundant smooth endoplasmic reticulum of the vesicular type and rod-like or oval-shaped mitochond…
Qualitative mucin disorders in patients with primary Sjögren's syndrome:a literature review
2020
Background It is a common opinion that Primary Sjögren Syndrome (pSS) damages the exocrine glands and determines the reduction of secreted saliva, some studies show that there are qualitative anomalies of the mucins produced in saliva, including MUC7, MUC5B, MUC1. The purpose of this study is to trace all the information useful to establish whether there is a qualitative or quantitative defect of the mucins in the pSS. Material and Methods We reviewed the literature by looking for publications relevant to the topic in electronic databases. Sixteen articles met the search criteria. The studies were divided into two categories, those that studied the rheological characteristics of the saliva …