Search results for "F14"
showing 10 items of 13 documents
Dissecting Abdominal Aortic Aneurysm Is Aggravated by Genetic Inactivation of LIGHT (TNFSF14)
2021
Abdominal aortic aneurysm (AAA), is a complex disorder characterized by vascular vessel wall remodeling. LIGHT (TNFSF14) is a proinflammatory cytokine associated with vascular disease. In the present study, the impact of genetic inactivation of Light was investigated in dissecting AAA induced by angiotensin II (AngII) in the Apolipoprotein E-deficient (Apoe−/−) mice. Studies in aortic human (ah) vascular smooth muscle cells (VSMC) to study potential translation to human pathology were also performed. AngII-treated Apoe−/−Light−/− mice displayed increased abdominal aorta maximum diameter and AAA severity compared with Apoe−/− mice. Notably, reduced smooth muscle α-actin+ area and Acta2 and C…
Cultural Distance and International Trade in Services: A Disaggregate View
2020
Abstract In this paper, we estimate the effect of “cultural distance” on bilateral trade in services. The measure of cultural distance we use is based on scores that reflect country averages of individuals’ attitudes towards inequality, self-orientation, competition, uncertainty, traditions, and indulgence. Controlling for standard ingredients of gravity equations, we show that an aggregate measure of cultural distance has a significantly negative effect on total bilateral services trade. Once we take a more disaggregate view, we find that the strength of this effect differs across various types of services and various aspects of cultural distance.
International trade and migrant networks: Is It really about qualifications?
2014
Personal characteristics of migrants could help to strengthen the impact of migrant networks on bilateral trade. While most of the attention has been focused on immigrants' educational attainment, this paper focuses on the relevance of the tasks carried out by migrants. Our empirical results confirm that the existence of a large number of foreign-born workers with managerial duties is critical to explain the reduction of transaction costs caused by migrant networks.
Exports of Spanish manufacturing firms and financial constraints
2020
We investigate the role of financial constraints on firms’ exporting behavior, including firms’ export decision, export intensity, firms starting to export decision, and exports persistence. Our financial constraints variable is a synthetic variable that summarizes information on different dimensions such as total assets, profitability, liquidity, solvency, repaying ability, and (new in this type of analyses) the cost of external financing. Using data on Spanish manufacturing for the period 1992–2014, we find evidence supporting that financial health is relevant to explain small and medium-sized enterprises (SMEs) exporting decisions and starting to export decisions but not those of large …
Estimating the gravity equation with the actual number of exporting firms
2013
Para estimar correctamente el efecto de los costes de comerciar sobre las exportaciones de las empresas, la ecuación de gravedad debe controlar por el número de empresas que opera en el mercado internacional. Debido a la ausencia de datos, estudios anteriores han controlado esta variable mediante técnicas econométricas que también pueden generar estimaciones sesgadas. Para superar estos problemas este trabajo estima una ecuación de gravedad utilizando una nueva base de datos de la OCDE y EUROSTAT , que incluye el número de empresas exportadoras en cada relación bilateral. Nuestros resultados muestran que no controlar el margen extensivo genera sesgos muy importantes en la estimación de los …
On the non-triviality of the torsion subgroup of the abelianized Johnson kernel
2022
The Johnson kernel is the subgroup of the mapping class group of a closed oriented surface that is generated by Dehn twists along separating simple closed curves. The rational abelianization of the Johnson kernel has been computed by Dimca, Hain and Papadima, and a more explicit form was subsequently provided by Morita, Sakasai and Suzuki. Based on these results, Nozaki, Sato and Suzuki used the theory of finite-type invariants of 3-manifolds to prove that the torsion subgroup of the abelianized Johnson kernel is non-trivial. In this paper, we give a purely 2-dimensional proof of the non-triviality of this torsion subgroup and provide a lower bound for its cardinality. Our main tool is the …
Generalized Dehn twists in low-dimensional topology
2021
The generalized Dehn twist along a closed curve in an oriented surface is an algebraic construction which involves intersections of loops in the surface. It is defined as an automorphism of the Malcev completion of the fundamental group of the surface. As the name suggests, for the case where the curve has no self-intersection, it is induced from the usual Dehn twist along the curve. In this expository article, after explaining their definition, we review several results about generalized Dehn twists such as their realizability as diffeomorphisms of the surface, their diagrammatic description in terms of decorated trees and the Hopf-algebraic framework underlying their construction. Going t…
Polymorphisms within the TNFSF4 and mapkapk2 loci influence the risk of developing invasive aspergillosis: A two-stage case control study in the cont…
2020
Here, we assessed whether 36 single nucleotide polymorphisms (SNPs) within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis (IA). We conducted a twostage case control study including 911 high-risk patients diagnosed with hematological malignancies that were ascertained through the aspBIOmics consortium. The meta-analysis of the discovery and replication populations revealed that carriers of the TNFSF4rs7526628T/T genotype had a significantly increased risk of developing IA (p = 0.00022). We also found that carriers of the TNFSF4rs7526628T allele showed decreased serum levels of TNFSF14 protein (p = 0.0027), and that their macrophages had a decreased fungi…
Does complexity explain the structure of trade?
2013
This paper analyzes whether complexity, measured by the number of skilled tasks that are performed in production, explains countries commodity trade structure. We modify the Romalis ( ) model to incorporate advantage differences in complexity across commodities together with differences in the number of mistakes made by workers in the production process in developed and developing countries as a source of comparative advantage. Our model predicts that the share of developed countries in world trade increases with products complexity. Empirical tests confirm this prediction. Moreover, we find that complexity complements the explanation provided by skillintensity on countries commodity trade …
Price discrimination and market power in export markets: The case of the ceramic tile industry.
2005
This paper combines the pricing-to-market equation and the residual demand elasticity equation to measure the extent of competition in the export markets of ceramic tiles, which has been dominated by Italian and Spanish producers since the late eighties. The findings show that the tile exporters enjoyed substantial market power over the period 1988-1998, and limited evidence that the export market has become more competitive over time.