Search results for "FLE"
showing 10 items of 3517 documents
Real-space grids and the Octopus code as tools for the development of new simulation approaches for electronic systems.
2015
This Open Access Article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Performance of Spectral Fitting Methods for vegetation fluorescence quantification
2010
The Fraunhofer Line Discriminator (FLD) principle has long been considered as the reference method to quantify solar-induced chlorophyll fluorescence (F) from passive remote sensing measurements. Recently, alternative retrieval algorithms based on the spectral fitting of hyperspectral radiance observations, Spectral Fitting Methods (SFMs), have been proposed. The aim of this manuscript is to investigate the performance of such algorithms and to provide relevant information regarding their use. FLD and SFMs were used to estimate F starting from Top Of Canopy (TOC) fluxes at very high spectral resolution (0.12 nm) and sampling interval (0.1 nm), exploiting the O2-B (687.0 nm) and O2-A (760.6 …
Effect of A Healthy Body Image intervention on risk- and protective factors for eating disorders: A cluster randomized controlled trial
2021
Accepted manuscript version, licensed CC BY-NC-ND 4.0. Objective - To investigate the immediate and 12-months effects of a school-based intervention aiming to reduce risk and enhance protective factors for eating disorder development in high school boys and girls. Method - In total, 4,149 adolescents from 30 high schools were eligible for inclusion and 2,446 consented to participate and were randomly allocated to the Healthy Body Image (HBI) intervention or a control group (classes as usual). The HBI intervention is multicomponent consisting of three workshops targeting body image, social media usage and lifestyle. Linear mixed model and intention-to-treat analyses were applied to investiga…
Targeted steel frames by means of innovative moment resisting connections
2021
Abstract The present paper proposes the use of stepped cross section devices on steel frames aiming at reproducing a pre-established target push-over curve. To this aim a Limited Resistance Plastic Device (LRPD) to be inserted along selected structural members is proposed. The following two main specific features for LRPD are required: any elastic flexural stiffness variation of the original selected member must be avoided; an ultimate plastic bending moment value equal to an assigned percentage of the original limit resistance value must be ensured. Steel frames equipped with LRPD are modeled by means of an extension of a recently proposed Fibre Smart Displacement Based (FSDB) beam element…
Por mis hijos lo que sea... o casi. Identidades de madres y padres que han vivido un divorcio
2014
A partir de los discursos de personas divorciadas o separadas (de generaciones nacidas entre 1965 y 1975), se analiza la configuración de las identidades parentales. El divorcio implica reorganizar aspectos relativos al cuidado de hijos/as, favoreciendo la reflexión sobre la propia identidad parental. Nuestra hipótesis problematiza los resultados de Solsona y Ferrer (2010), quienes destacan la centralidad del hecho de ser madres y padres entre las generaciones mayores. Destacan entre los resultados que las mujeres reubican la maternidad al mismo nivel de importancia que otros aspectos de sus trayectorias vitales, mientras que los hombres tienden a idealizar la paternidad.; From the discours…
La pratica riflessiva nella formazione degli insegnanti
2021
All’inizio del XX secolo, John Dewey introdusse il concetto di riflessione in campo pedagogico e, da allora, il suo lavoro ha rappresentato un punto fermo per gli studi successivi sulla professionalità docente. Nella società della conoscenza è, infatti, riconosciuta una relazione circolare nel processo d’insegnamento tra la progettazione didattica e la formazione dei docenti, sia iniziale che in servizio. La società della conoscenza richiede, pertanto, di aggiungere a un sapere prettamente teorico o tecnico, un sapere prassico, capace di analizzare e comprendere le esperienze singolari che si stanno vivendo e di decidere quali azioni mettere in atto.
Nuovi derivati della Dopamina nell’Addiction da sostanze d’abuso: studi preclinici su modelli sperimentali murini
Studies on a new potential dopaminergic agent: in vitro BBB permeability, in vivo behavioural effects and molecular docking evaluation.
2015
2-Amino-N-[2-(3,4-dihydroxy-phenyl)-ethyl]-3-phenyl-propionamide (DA-PHEN) has been previously synthesized to obtain a potential prodrug capable of release dopamine (DA) into CNS. However, DA-PHEN could act per se as a dopaminergic drug. In this study, the permeability transport (Pe), obtained by parallel artificial permeability assay (PAMPA), indicated a low passive transcellular transport (Pe = 0.32 ± 0.01 × 10(-6 )cm/s). Using the Caco-2 cell system, the Papp AP-BL in absorptive direction (3.36 ± 0.02 × 10(-5 )cm/s) was significantly higher than the Papp BL-AP in secretive direction (1.75 ± 0.07 × 10(-5 )cm/s), suggesting a polarized transport. The efflux ratio (Papp AP-BL/Papp BL-AP = 0…
Ultraviolet reflection and female mate choice in the pied flycatcher, Ficedula hypoleuca
2002
In pied flycatchers females seem to prefer male territory quality rather than male characteristics, and the results of female mate choice experiments are divergent. In this outdoor aviary study, we examined how altering the ultraviolet reflection of males affects female mate choice behaviour. We chose pairs of males with similar human-visible dorsal colour and morphological traits. We then reduced the proportional ultraviolet reflectance in one male with sunscreen chemicals. The other male was treated with a chemical that slightly increased the ultraviolet reflectance of the plumage. In the experiment females clearly preferred males with slightly increased ultraviolet reflection. Our result…
A survey on IVIVC/IVIVR development in the pharmaceutical industry – Past experience and current perspectives
2017
The present work aimed to describe the current status of IVIVC/IVIVR development in the pharmaceutical industry, focusing on the use and perception of specific approaches as well as successful and failed case studies. Two questionnaires have been distributed to 13 EFPIA partners of the Oral Biopharmaceutics Tools Initiative and to the Pharmacokinetics Working Party of the European Medicines Agency in order to capture the perspectives and experiences of industry scientists and agency members, respectively. Responses from ten companies and three European Agencies were received between May 21st 2014 and January 19th 2016. The majority of the companies acknowledged the importance of IVIVC/IVIVR…