Search results for "FOOD INTAKE"
showing 10 items of 132 documents
How important are satiation and satiety for weight regulation?
2013
Abstract: This chapter discusses how body weight is regulated in adult humans by a cybernetic-like process, whose main physiological response is the control of food intake, while energy expenditure modulation probably only passively participates in the adjustment of energy balance. The historical emergence and scientific definition of the two concepts ‘satiety’ and ‘satiation’ are recapitulated and their respective roles in body weight regulation are discussed. The original methodology developed to differentiate and separately quantify the roles of satiety and satiation in the quantitative control of food intake of healthy human subjects is described. Finally, the respective importance of s…
Rôle des lipides dans la régulation du comportement alimentaire
2008
Obesity constitutes a major public health problem for the 21 st Century, with its epidemic spread worldwide, particularly in children. The overconsumption of fatty foods greatly contributes to this phenomenon. Rodents and humans display a spontaneous preference for lipid-rich foods. But why are lipids so attractive? What are the molecular mechanisms involved? The purpose of this mini review is to explore few basic questions raised by recent data providing evidences on the relationships between dietary lipids and feeding behavior.
Indirect estimation of stomach volume of rainbow trout Oncorhynchus mykiss (Walbaum)
2005
The main hypothesis of this study was that if stomach volume is correlated with food intake it can be estimated without laborious and destructive direct measurement. Rainbow trout, Oncorhynchus mykiss (Walbaum), ca. 500^1300 g, were starved for 1, 4, 8 or16 days at151C after which they were fed in excess with dry pellets containing known amounts of X-raydense markers. Immediately after feeding the ¢sh were killed, X rayed and weighed. Then the stomach was dissected, its contents removed and weighed, and stomach volume was measured. X-ray plates were developed and feed intake was estimated based on the amount of marker. All measured variables correlated positively with stomach volume. The be…
The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice
2014
Overfeeding causes rapid synaptic remodeling in hypothalamus feeding circuits. Polysialylation of cell surface molecules is a key step in this neuronal rewiring and allows normalization of food intake. Here we examined the role of hypothalamic polysialylation in the long-term maintenance of body weight, and deciphered the molecular sequence underlying its nutritional regulation. We found that upon high fat diet (HFD), reduced hypothalamic polysialylation exacerbated the diet-induced obese phenotype in mice. Upon HFD, the histone acetyltransferase MOF was rapidly recruited on the St8sia4 polysialyltransferase-encoding gene. Mof silencing in the mediobasal hypothalamus of adult mice prevented…
En EHPAD, repérer les petits mangeurs et adapter leur alimentation : quel coût, quel bénéfice ?
2018
National audience; Des pesées alimentaires ont montré qu'une large majorité de personnes âgées vivant en EHPAD (Etablissement d'Hébergement pour Personne Âgée Dépendante) ne mange pas suffisamment pour couvrir ses besoins nutritionnels. Il s'ensuit un coût pour les personnes elles-mêmes (augmentation du risque nutritionnel), ainsi qu'un coût pour l'environnement (gaspillage alimentaire). Dans ce contexte, l'objectif de RENESSENS était de proposer aux résidents d'EHPAD une offre alimentaire adaptée à leurs capacités d'ingestion afin de couvrir leurs besoins nutritionnels. Pour cela, nous avons réalisé une étude clinique de 6 mois dans deux maisons de retraite, l'une contrôle (n=43) et l'autr…
Taste of Fat and Obesity: Different Hypotheses and Our Point of View
2022
Obesity results from a temporary or prolonged positive energy balance due to an alteration in the homeostatic feedback of energy balance. Food, with its discriminative and hedonic qualities, is a key element of reward-based energy intake. An alteration in the brain reward system for highly palatable energy-rich foods, comprised of fat and carbohydrates, could be one of the main factors involved in the development of obesity by increasing the attractiveness and consumption of fat-rich foods. This would induce, in turn, a decrease in the taste of fat. A better understanding of the altered reward system in obesity may open the door to a new era for the diagnosis, management and treatment of th…
Toward a link between brain plasticity and satiety
2021
International audience
Vieillissement, adaptation alimentaire au grand âge et petit appétit : le petit mangeur âgé
2018
Atteindre un âge canonique de 100 ans avec toutes les fonctions cognitives et physiques de l'âge adulte est le souhait de chacun. Pour autant, avec le vieillissement, l'héritage génétique, les conditions de vie durant la vie adulte et certains accidents de la vie peuvent faire basculer des personnes âgées plus rapidement que d'autres vers la dépendance, la dénutrition, la fragilité. Simone de Beauvoir écrivait « la sénescence n'est pas une pente que chacun descend à la même vitesse. C'est une volée de marches irrégulières que certains dégringolent plus vite que d'autres ». Le vieillissement a ses surprises et pour un même âge de 90 ans, alors que certains peuvent rivaliser avec les plus jeu…
The effectiveness of personalized design to feed elderly people
2015
Beyond the physiological age, the elderly population is characterized by a high heterogeneity in terms of physical, psychological and sociological status (Maître et al, 2015). Regarding eating behavior, several studies have highlighted a large inter-individual variability in chemosensory abilities (i.e. the ability to perceive an odor or a taste; Sulmont-Rossé et al, 2015) and oral-heath status (i.e. dental status, salivary flow; ALIMASSENS project), as well as inter-individual variability in food preference and food intake (AUPALESENS project). However, the food offer dedicated to the elderly population, and in particular to elderly people who needs help to obtain and/or prepare food for t…
Proximal versus distal contextual factors: which impact on meal pleasure and food intake in the elderly living in a nursing home?
2014
Poster présenté lors de la conférence; Introduction: Several authors pointed out the importance of meal context on food intake in nursing home. Some authors assessed the impact of context improvement on food intake in nursing home, but they assessed ‘holistic’ strategies by improving physical environment, increasing choice level, changing staff organization… (Abbott et al. 2013). Despite some of these interventions were effective, these strategies are costly and thus difficult to be implemented in nursing home. The aim of the present experiment was to assess the impact of single contextual factors, three proximal factors (food contextual factors) and three distal factors (non-food contextua…