Search results for "FS"

Aberrant gene expression profiles in Mediterranean sea urchin reproductive tissues after metal exposures

2019

Abstract Marine organisms are simultaneously exposed to numerous pollutants, among which metals probably represent the most abundant in marine environments. In order to evaluate the effects of metal exposure at molecular level in reproductive tissues, we profiled the sea urchin transcriptional response after non-lethal exposures using pathway-focused mRNA expression analyses. Herein, we show that exposures to relatively high concentrations of both essential and toxic metals hugely affected the gonadic expression of several genes involved in stress-response, detoxification, transcriptional and post-transcriptional regulation, without significant changes in gonadosomatic indices. Even though …

Tirant is a new member of the gypsy family of retrotransposons in Drosophila melanogaster.

2000

In this paper, we propose a consensus sequence for a putative complete Tirant retrotransposon. Several defective copies, as well as relevant sequences available in databases have been analyzed. The putative complete Tirant element is 8533 bp long, and presents all the structural features of a retroviruslike transposable element of the gypsy family. It contains three ORFs (open reading frames) that encode putative products resembling the retroviral Gag, Pol, and Env proteins. Southern blot analyses show that complete and defective Tirant elements are widespread in Drosophila melanogaster. The different hybridization patterns observed in several natural populations of this species suggest tha…

The relationship between genetic risk variants with brain structure and function in bipolar disorder: A systematic review of genetic-neuroimaging stu…

2017

Genetic-neuroimaging paradigms could provide insights regarding the pathophysiology of bipolar disorder (BD). Nevertheless, findings have been inconsistent across studies. A systematic review of gene-imaging studies involving individuals with BD was conducted across electronic major databases from inception until January 9th, 2017. Forty-four studies met eligibility criteria (N = 2122 BD participants). Twenty-six gene variants were investigated across candidate gene studies and 4 studies used a genome-wide association approach. Replicated evidence (i.e. in >2 studies) suggests that individuals with BD carrying the BDNF Val66Met risk allele could have reduced hippocampal volumes compared …

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases

2005

The tumor suppressor phosphatase PTEN is a key regulator of cell growth and apoptosis that interacts with PDZ domains from regulatory proteins, including MAGI-1/2/3, hDlg, and MAST205. Here we identified novel PTEN-binding PDZ domains within the MAST205-related proteins, syntrophin-associated serine/threonine kinase and MAST3, characterized the regions of PTEN involved in its interaction with distinctive PDZ domains, and analyzed the functional consequences on PTEN of PDZ domain binding. Using a panel of PTEN mutations, as well as PTEN chimeras containing distinct domains of the related protein TPTE, we found that the PTP and C2 domains of PTEN do not affect PDZ domain binding and that the …

On the choice of tool material in friction stir welding of titanium alloys

2012

Structure et croissance de nanophases supportées d'oxyde de tungstène

2010

Tungsten trioxide nanorods can be elaborated on muscovite mica substrate through simple vapor deposition method. Growth of rods seems to follow a Stranski-Krastanov model. Their crystallography was investigated by TEM and reveals the presence of hexagonal phase. Such a metastable structure occurs from an interfacial hexagonal tungsten bronze which grows epitaxially on the substrate. This bronze phase contains potassium atoms coming from mica. Concerning the thickest rods, a monoclinic phase grows on the top of the hexagonal one. The hexagonal structure is thermally very stable: after annealing at 600°C, this phase is still detected whereas the rod morphology is destroyed. This point seems t…

Anthropogenic travertine between History, Archaeology and Environment: a geoarchaeological study of the Roman site of Jebel Oust, Tunisia.

2013

Travertine, known as lapis tiburtinus during Roman times, are continental limestones precipitated in calcareous environments from thermal waters of hot springs (travertine) or cool waters of karstic springs (calcareous tufa). This phenomenon is well-known during Classical Antiquity and had been described by several ancient authors (Strabo, Pliny the Elder, Vitruvius) who depicted a stone that forms extremely rapidly, a stone that outlines the landscape and which is largely used for construction (e.g. The Colosseum in Roma, the Greek temple at Segesta in Sicily). These deposits are widespread on Earth’s surface showing various morphologies and are great sedimentary records of climatic and hy…

Extended Environmental Contour Methods for Long-Term Extreme Response Analysis of Offshore Wind Turbines1

2020

Abstract Environmental contour method is an efficient method for predicting the long-term extreme response of offshore structures. The traditional environmental contour is obtained using the joint distribution of mean wind speed, significant wave height, and spectral peak period. To improve the accuracy of traditional environmental contour method, a modified method was proposed considering the non-monotonic aerodynamic behavior of offshore wind turbines. Still, the modified method assumes constant wind turbulence intensity. In this paper, we extend the existing environmental contour methods by considering the wind turbulence intensity as a stochastic variable. The 50-year extreme responses …

Zīmes, to semantika un Tarkovska ietekme Mohameda Malasa filmā “Al-Leil”

2017

Pat laikā līdz šī brīža militārajam konfliktam, kas pazīstams ar nosaukumu “Sīrijas pilsoņu karš”, kā arī vismaz pirmajos tā gados, Sīrijas kino ar tā avangarda vārdiem (tostarp Muhameds Malass, Osama Muhameds, Omārs Amiralajs u.c.) identificēts kā viena no vai pat vienīgā efektīvā komunikācija starp autoritāro režīmu Damaskā un Sīrijas intelektuāļu aprindām. Jāatzīmē, ka tas nebūtu iespējams bez izglītības, ko Sīrijas režisori un scenāristi guva Vissavienības Kinematogrāfijas institūtā Maskavā. Šis faktors, kombinācijā ar iespējām ražot filmas – kaut arī tas notika ierobežotā apmērā un, spītējot grūtībām, tomēr nodrošināja starptautisku atzinību. Tas, savukārt, bija izdevīgi arī Sīrijas va…

Influence of artificial reefs on the surrounding infauna: Analysis of meiofauna

2002

We adopted a bottom-up approach in studying the effect of two artificial reefs in contrasting environmental conditions (sandy-mud and meso-eutrophic in the Adriatic Sea versus coarse sands and oligotrophic in the Tyrrhenian Sea) on the surrounding environment by assessing changes in the meiofauna. The spatial distribution of meiofaunal assemblages was established along a transect running from within each reef to well outside its direct sphere of influence, along with information on the trophic conditions of sediments (chloropigments, proteins, carbohydrates and total organic matter). Although total densities were significantly higher in the Adriatic than in the Tyrrhenian, the meiofauna dis…