Search results for "Farmaceutica"
showing 10 items of 582 documents
Virtual lock and key approach: the revival of Fischer model
2009
New Topsentin analogs as inhibitors of biofilm formation
Paracentrin 1, a synthetic antimicrobial peptide fragment of a beta-thymosin from the sea-urchin Paracentrotus lividus, interferes with staphylococca…
2014
Molecular and taxonomic characterization of a endophytic fungus isolated from Helleborus bocconei subsp. intermedius (Ranunculaceae)
2014
A non-sporulating fungus was isolated from different organs of Helleborus bocconei subsp. intermedius (Ranunculaceae) endemic to southern Italy and Sicily, known for the traditional use of dried roots in the treatment of lung diseases of cattle and horses. Molecular characterization of endophytic fungus based on the internal transcribed spacer (ITS) region of the rRNA gene sequences was done. The DNA sequence of full length ITS region of the studied fungus was a 100% match to that of Chaetomium strumarium strain dH 21642 (GenBank accession number JX280851.1). The morphological characters of colony and mycelium of this microfungus are reported here.
Potential allelopathic activity ofSideritis italica(Miller) Greuter et Burdet essential oil
2011
Sideritis italica (Miller) Greuter et Burdet is a widespread Mediterranean Lamiacea. Essential oils from S. italica flowerheads and leaves were extracted by hydrodistillation and then tested for their potential allelopathic activity against Raphanus sativus L. (Magnoliophyta) and the moss Tortula muralis (Hedw.) (Bryophyta), two organisms already tested for allelopathy, and against two bryophytes growing in the same environment as S. italica: the moss Bryum capillare Hedw. and the liverwort Lunularia cruciata (L.) Dum. For R. sativus, we considered seed germination and root and epicotyl growth. For the mosses, we used spore germination and protonemata development, while for the liverwort, w…
Essential oil composition and antifeedant properties of Bellardia trixago (L.) All. (sin. Bartsia trixago L.) (Scrophulariaceae)
2008
Design, sinthesis and anticancer properties of new cdks inhibitors
2010
La chemiometria ed il molecular modeling in ausilio alla scoperta ed all’ottimizzazione di lead compounds
2008
Nucleophilic substitutions in the isoindole series as a valuable tool to synthesize derivatives with antitumor activity
2011
Abstract A novel synthetic approach to the synthesis of 3-substituted isoindoles through nucleophilic substitution of 3-halo derivatives by charged carbon, and neutral nitrogen, oxygen, and sulfur nucleophiles, assisted by a 1-acyl group, is reported. Aryl-thio-isoindoles, obtained through a direct nucleophilic substitution with sulfur nucleophiles, showed cytotoxic activity, with GI50 values from micromolar to sub-micromolar concentrations, against the total number of cell lines investigated.
‘Interrupted’ diazotization of 3-aminoindoles and 3-aminopyrroles
2014
Abstract ‘Interrupted’ diazotization of 3-aminoindoles and 3-aminopyrroles, achieved by quenching with cold water immediately after the addition of nitrite, led, in good yields, to stable compounds whose structures were identified to be the diazonium species with nitrate as the counter ion, which show no saline character.