Search results for "Fingerprint"
showing 10 items of 215 documents
Human pathology in NCL
2013
AbstractIn childhood the neuronal ceroid lipofuscinoses (NCL) are the most frequent lysosomal diseases and the most frequent neurodegenerative diseases but, in adulthood, they represent a small fraction among the neurodegenerative diseases. Their morphology is marked by: (i) loss of neurons, foremost in the cerebral and cerebellar cortices resulting in cerebral and cerebellar atrophy; (ii) an almost ubiquitous accumulation of lipopigments in nerve cells, but also in extracerebral tissues. Loss of cortical neurons is selective, indiscriminate depletion in early childhood forms occurring only at an advanced stage, whereas loss of neurons in subcortical grey-matter regions has not been quantit…
Application of mtDNA sequence analysis in forensic casework for the identification of human remains
2000
Abstract In four forensic cases of unidentified skeletal remains investigated in the last year, we were able to attach three to missing persons. In one case we could show that the discovered bone sample did not fit to a missing child. The method for mitochondrial DNA analysis for the routine identification of skeletal remains was established in our institute by typing bone samples of defined age obtained from Frankfurt's cemetery. Reproducible results were obtained for bones up to 75 years old. For analysis the bone samples were pulverised to fine powder, decalcified and DNA was extracted. From the DNA we amplified a 404-bp fragment from HV-1 and a 379-bp fragment from HV-2 of the mtDNA con…
Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia.
2013
Mutations in the nucleophosmin 1 (NPM1) gene are considered a founder event in the pathogenesis of acute myeloid leukemia (AML). To address the role of clonal evolution in relapsed NPM1-mutated (NPM1mut) AML, we applied high-resolution, genome-wide, single-nucleotide polymorphism array profiling to detect copy number alterations (CNAs) and uniparental disomies (UPDs) and performed comprehensive gene mutation screening in 53 paired bone marrow/peripheral blood samples obtained at diagnosis and relapse. At diagnosis, 15 aberrations (CNAs, n = 10; UPDs, n = 5) were identified in 13 patients (25%), whereas at relapse, 56 genomic alterations (CNAs, n = 46; UPDs, n = 10) were detected in 29 patie…
BYOTYPES AND RANDOMLY AMPLIFIED POLYMORPHIC DNA (RAPD) PROFILES OF SUBGINGIVAL CANDIDA ALBICANS ISOLATES IN HIV INFECTION
2005
ABSTRACT: A group of subgingival isolates of C. albicans recovered from Italian HIV-positive (HIV+) subjects were characterized both phenotypically and genotypically. Phenotyping of the isolates was carried out by a biotyping method based on the enzyme profiles, carbohydrate assimilation patterns and boric acid resistance of the yeasts. Genotyping was performed through randomly amplified polymorphic DNA (RAPD) analysis. Five biotypes were found among the 29 subgingival C. albicans strains examined. The predominant biotypes were A1R (55.17%), A1S (24.14%), and A2R (13.79%), while the biotypes A11R and A13R were represented by a single isolate each. RAPD profiles identified 15 genotypes among…
Volatile organic compounds fingerprint of Alzheimer’s disease.
2015
Alzheimer's disease (AD) is a profoundly life changing condition and once diagnosis occurs, this is typically at a relatively late stage into the disease process. Therefore, a shift to earlier diagnosis, which means several decades before the onset of the typical manifestation of the disease, will be an important step forward for the patient. A promising diagnostic and screening tool to answer this purpose is represented by breath and exhaled volatile organic compounds (VOCs) analysis. In fact, human exhaled breath contains several thousand of VOCs that vary in abundance and number in correlation with the physiological status. The exhaled VOCs reflect the metabolism, including the neuronal …
Chemical partitioning and DNA fingerprinting of some pistachio (Pistacia vera L.) varieties of different geographical origin
2019
The genus Pistacia (Anacardiaceae family) is represented by several species, of which only P. vera L. produces edible seeds (pistachio). Despite the different flavor and taste, a correct identification of pistachio varieties based on the sole phenotypic character is sometimes hard to achieve. Here we used a combination of chemical partitioning and molecular fingerprinting for the unequivocal identification of commercial pistachio seed varieties (Bronte, Kern, Kerman, Larnaka, Mateur and Mawardi) of different geographical origin. The total phenolic content was higher in the variety Bronte followed by Larnaka and Mawardi cultivars. The total anthocyanin content was higher in Bronte and Larnak…
mtDNA analysis of the human remains buried in the sarcophagus of Federico II
2005
Abstract The sarcophagus containing the remains of Federico II, located in the Cathedral of Palermo (Sicily, Italy), was opened on 1998 to perform a multidisciplinary survey [1]. Next to the remains of Federico II and in close contact with them were laying two other skeletons belonging, according to historical records, to Pietro II di Aragona and to an anonymous person (“The Third Individual”), probably a woman. The bones appeared severely deteriorated. Chemical analysis performed on bone samples excluded that the bodies underwent some kind of embalming process. The analysis of mtDNA from bone samples taken from the three skeletons was successful in only one of the two labs involved. The HV…
Combining Auto-Encoder with LSTM for WiFi-Based Fingerprint Positioning
2021
Although indoor positioning has long been investigated by various means, its accuracy remains concern. Several recent studies have applied machine learning algorithms to explore wireless fidelity (WiFi)-based positioning. In this paper, we propose a novel deep learning model which concatenates an auto-encoder with a long short term memory (LSTM) network for the purpose of WiFi fingerprint positioning. We first employ an auto-encoder to extract representative latent codes of fingerprints. Such an extraction is proven to be more reliable than simply using a deep neural network to extract representative features since a latent code can be reverted back to its original input. Then, a sequence o…
Fast Fingerprints Classification Only Using the Directional Image
2007
The classification phase is an important step of an automatic fingerprint identification system, where the goal is to restrict only to a subset of the whole database the search time. The proposed system classifies fingerprint images in four classes using only directional image information. This approach, unlike the literature approaches, uses the acquired fingerprint image without enhancement phases application. The system extracts only directional image and uses three concurrent decisional modules to classify the fingerprint. The proposed system has a high classification speed and a very low computational cost. The experimental results show a classification rate of 87.27%.
Fingerprint Quality Evaluation in a Novel Embedded Authentication System for Mobile Users
2015
The way people access resources, data and services, is radically changing using modern mobile technologies. In this scenario, biometry is a good solution for security issues even if its performance is influenced by the acquired data quality. In this paper, a novel embedded automatic fingerprint authentication system (AFAS) for mobile users is described. The goal of the proposed system is to improve the performance of a standard embedded AFAS in order to enable its employment in mobile devices architectures. The system is focused on the quality evaluation of the raw acquired fingerprint, identifying areas of poor quality. Using this approach, no image enhancement process is needed after the …