Search results for "Fires"
showing 10 items of 129 documents
Enhancement of nortriptyline penetration through human epidermis: influence of chemical enhancers and iontophoresis.
2008
Abstract Different known percutaneous chemical enhancers and iontophoresis have been tested in-vitro to study their ability to increase transdermal absorption of nortriptyline hydrochloride (20 mg mL−1). The chemicals 1-dodecanol, Span 20, Azone, (R)-(+)-limonene or isopropyl myristate were used as an overnight pretreatment at 5% (w/w) in ethanol. Furthermore, isopropyl myristate (20%, w/w) and propylene glycol (15%, w/w) were tested in the same vehicle. Iontophoresis was applied directly to the nortriptyline hydrochloride donor solution for three different concentrations (20, 2 and 0.5 mgmL−1). The chemical enhancers slightly increased the nortriptyline transdermal flux but iontophoresis w…
The decline of the cork oak growing in Sicily is accompanied by the loss of the functions proper to agroforestry systems
2021
The cork oak is one of the most important tree species in the Mediterranean basin, where it covers more than 2 million hectares. Among evergreen oaks, Quercus suber stands out for the variety of cultural systems in which it has been successfully employed, including typical agroforestry systems. Accordingly, a wide range of ecosystem services may be associated to cork oak, including the preservation of biodiversity, carbon sequestration and forage production. In the Mediterranean, the cork oak represents a key species for many natural and seminatural landscapes and habitats, as well as playing a prominent role for the economic and social development of local communities. However, there is in…
Holocene treeline in the northern Andes (Ecuador): new evidence from soil charcoals
2006
Soil charcoals represent a record for palaeoecological studies. For the first time pedoanthracology is applied to northern Andes of Ecuador to study the Holocene treeline. The first results show that the upper treeline was lower than today in the late Pleistocene and in the Middle Holocene. A wide amount of charcoals dated ca. 13000 cal. yr. BP could be caused by fires linked to the first presence of man at these altitudes.
Enhanced In Situ Availability of Aphanizomenon Flos-Aquae Constituents Entrapped in Buccal Films for the Treatment of Oxidative Stress-Related Oral D…
2019
In recent years, the key role of oxidative stress in pathogenesis of oral diseases has been emphasized and the use of antioxidant agents has been encouraged. Aphanizomenon flos-aquae (AFA) is a unicellular blue-green alga with antioxidant and anti-inflammatory properties. The aim of this study was the formulation and characterization of mucoadhesive thin layer films loaded with AFA, finalized to the treatment of oxidative stress (OS)-related oral diseases. First, to enhance the bioavailability of AFA constituents, the raw food grade material was appropriately treated by a high frequency homogenization able to disrupt cell walls. Thus, Eudragit®
On Pathways for Small Molecules Into and Out of Human Hair Fibers
1996
This paper represents an experimental approach of histology of the human hair fiber in dyeing and diffusion phenomena and its contribution to the interpretation of hair analysis results for drug abuse. Rhodamine B was applied to human hair fibers from either aqueous solution or methanol/ethanol solvent. The experiments were performed on natural hair of different ethnic groups as well as on extensively bleached hair strands. The microscopical study of the pathway of diffusion of rhodamine B into the hair fibers indicated that the reagent had entered the unmodified fibers at the scale edges between the cuticle cells. At the beginning of the diffusion process intercellular diffusion was the pr…
A modelistic approach showing the importance of the stagnant aqueous layers in in vitro diffusion studies, and in vitro-in vivo correlations
1991
Abstract The present study deals with the role of the aqueous diffusion layers on the in vitro penetration of xenobiotics across artificial lipoidal membranes, and their ability to reproduce biophysical absorption models when in vivo results are to be simulated from the in vitro tests. The aqueous boundary layers which are invariably formed on artificial lipoidal membranes can be optionally preserved or disrupted, according to the type of absorption site which should be simulated, a condition which could reasonably lead to a better correspondence between in vitro and in vivo results; in practice, disruption of water layers can be easily achieved by a synthetic surfactant solution at its cri…
Mucoadhesive Polymeric Films to Enhance Barbaloin Penetration Into Buccal Mucosa: a Novel Approach to Chemoprevention.
2018
Nowadays, chemoprevention by administering natural supplements is considered an attractive strategy to reverse, suppress, or prevent the evolution of premalignant oral lesions. In particular, Barbaloin exhibits anti-proliferative, anti-inflammatory, and anti-cancer properties, and it results useful in multi-therapy with classic chemotherapeutics. Therefore, in this work, mucoadhesive buccal films, as locoregional drug delivery system able to provide a targeted and efficient therapeutic delivery of Barbaloin, are proposed. Thus, Aloin extract-loaded Eudragit (R) RL100 or Eudragit (R) RS100-based buccal films were designed in order to obtain an easily self-administrable formulation capable of…
Comparison between Willingness-to-Pay expressed by a panel of forestry experts and by a sample of non-expert respondents in a pilot survey conducted …
2005
This work deals with an empirical analysis aiming to check the possibility to substitute a panel of forestry experts for a sample of non-expert respondents in a pilot survey for a CVM study. This methodology in the case study has focussed on the estimate of the economic value associated with the reduction in wood fire risk in a protected area of southern Sicily. The experiment consisted in carrying out two surveys by means of the same questionnaire with an open-ended elicitation question for WTP’s. The first survey was addressed to a sample of 227 “non-expert” respondents, whereas in the second one 15 forest technicians working in Sicily were interviewed in their quality of experts in fores…
Multi-Frequency Estimation of Canopy Penetration Depths from SMAP/AMSR2 Radiometer and IceSAT Lidar Data
2018
In this study, the $\tau-\omega$ model framework is used to derive extinction coefficient and canopy penetration depths from multi-frequency SMAP and AMSR2 retrievals of vegetation optical depth together with ICESat LiDAR vegetation heights. The vegetation extinction coefficient serves as an indicator of how strong absorption and scattering processes within the canopy attenuate microwaves at $\mathrm{L}$ and C-band. Through inversion of the extinction coefficient, the penetration depth into the canopy can be obtained, which is analyzed on local (Sahel, Illinois) and continental scale (Africa, parts of North America) as well as for a one year time series (04/2015-04/2016). First analyses of …
Estimation of vegetation loss coefficients and canopy penetration depths from SMAP radiometer and IceSAT lidar data
2017
In this study the framework of the τ — ω model is used to derive vegetation loss coefficients and canopy penetration depths from SMAP multi-temporal retrievals of vegetation optical depth, single scattering albedo and ICESat lidar vegetation heights. The vegetation loss coefficients serve as a global indicator of how strong absorption and scattering processes attenuate L-band microwave radiation. By inverting the vegetation loss coefficients, penetration depths into the canopy can be obtained, which are displayed for the global forest reservoirs. A simple penetration index is formed combining vegetation heights and penetration depth estimates. The distribution and level of this index reveal…