Search results for "Flank"

showing 10 items of 22 documents

Lack of antiandrogenic effects of topical bifonazole on sebaceous glands and hairs in the hamster flank organ.

1993

The activity of topically applied bifonazole was evaluated in vivo in the three androgen-dependent structures of the hamster flank organ, i.e. the pigmented spot, sebaceous glands and hairs. Topical bifonazole in our experience did not demonstrate any morphological effect on sebaceous gland and hair even when applied in the dosage of 3 mg/cm<sup>2</sup>/day. On the basis of our morphometric results we can conclude that topically applied bifonazole does not interfere with cutaneous androgen metabolic transformations in the pilosebaceous unit of the flank organ.

Sebaceous glandPathologymedicine.medical_specialtyFlankAntifungal AgentsPhysiologymedicine.drug_classAdministration TopicalBifonazoleHamsterDermatologyBiologyAntiandrogenSebaceous GlandsIn vivoInternal medicineCricetinaemedicineAnimalsPharmacologyMesocricetusPigmentationImidazolesAndrogen AntagonistsGeneral MedicineAndrogenbiology.organism_classificationmedicine.anatomical_structureEndocrinologyFemaleCabellomedicine.drugHairSkin pharmacology : the official journal of the Skin Pharmacology Society
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Radon measurements in the SE and NE flank of Mt. Etna (Italy)

2007

Abstract Soil Radon has been monitored at two fixed sites located in the northeastern and southeastern flank of Mt. Etna. In this study we report the comparison between in-soil Radon concentration trend recorded in the SE flank and that one recorded in the NE one, where an in-soil Radon detection system is operating since 2001. The aim of this work was to implement the investigation area finding a suitable radon detection site, in the south-east flank of Mt. Etna, in order to better understand possible links between Radon anomalies and volcano dynamic. Radon data collected in NE and SE sites were compared with the volcanic tremor, frequency of occurrence of earthquakes and seismic strain-re…

geographyFlankRadiationgeography.geographical_feature_categoryFrequency of occurrenceMt. Etnachemistry.chemical_elementRadonInduced seismicityPower spectrumVolcanochemistryRadonSettore GEO/11 - Geofisica ApplicataInstrumentationSeismologyGeology
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Geometric description of flanking structures

2005

Present nomenclature of faults and flanking structures is ambiguous. This paper presents a system for description of flanking structures, based on geometric parameters and independent of kinematic frame. The description can be made using two levels of accuracy. A qualitative method is described using four geometric features: tilt, slip, lift and roll. This method is suggested for practical use in the field, since it does not involve measurements or complicated procedures. In parallel, a quantitative approach is also presented, based on analytical modelling of Bezier curves. This method requires measurement of geometric features and involves mathematical treatment, but allows comparison betw…

Flanking maneuverGeologyBézier curveGeometrySlip (materials science)KinematicsMathematicsJournal of Structural Geology
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Electron microprobe technique for the determination of iron oxidation state in silicate glasses

2018

We present a new calibration for the determination of the iron oxidation state in silicate glasses by electron probe microanalysis (EPMA) with the "flank method." This method is based on the changes in both intensity and wavelength of the FeLα and FeLβ X-ray emission lines with iron oxidation state. The flank method utilizes the maximum difference for the FeLα and FeLβ spectra observed at the peak flanks between different standard materials, which quantitatively correlates with the Fe2+ content. Provided that this correlation is calibrated on reference materials, the Fe2+/ΣFe ratio can be determined for samples with known total Fe content. Two synthetic Fe-rich ferric and ferrous garnet end…

MicroprobeMaterials science010504 meteorology & atmospheric sciencesInorganic chemistryElectron microprobe010502 geochemistry & geophysics01 natural sciencesRedoxflank methodferric-ferrous ratioGeophysicsGeochemistry and PetrologyOxidation stateredox statepillow glassesSilicate glassMicroprobesilicate glasses0105 earth and related environmental sciences
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Primary megaureter in adults.

1984

The terminology of megaureters, their histological findings and etiology vary greatly in the literature. Primary obstructed megaureters must be clearly differentiated from megaureters caused by infravesical obstruction. The characterization and therapeutical consequences of the two types also differ. In a retrospective study, 43 adult patients with 54 primary obstructed megaureters (male:female = 30:13) were studied. This diagnosis excluded infravesical obstruction, reflux and neurogenic disorders. The main symptoms were flank pain, infection and hematuria. An operation was performed in 25 patients; 29 were treated conservatively. The criteria for surgery are discussed in relation to sympto…

AdultMalemedicine.medical_specialtyFlank painMegaureterbusiness.industryUrologyRefluxRenal functionRetrospective cohort studymedicine.diseaseSurgeryRadiographyUretermedicine.anatomical_structureEtiologymedicineHumansFemaleUreterbusinessUpper urinary tractDilatation PathologicUreteral ObstructionEuropean urology
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Lack of genetic association of neutral endopeptidase (NEP) with complex regional pain syndrome (CRPS)

2010

Complex regional pain syndrome (CRPS) is a condition that is characterized by severe pain and exaggerated neurogenic inflammation, which may develop after injury or surgery. Neurogenic inflammation is mediated by neuropeptides, such as calcitonin gene-related peptide (CGRP) and substance P (SP) that are released from nociceptors. Genetic factors may play a role in CRPS as was suggested by the occurrence of familial cases and several genetic association studies investigating mainly the human leukocyte antigen (HLA) system. Here we investigated the role of neutral endopeptidase (NEP), a key enzyme in neuropeptide catabolism. NEP dysfunction resulting in reduced inactivation of neuropeptides m…

AdultMalemedicine.medical_specialtyLinkage disequilibrium5' Flanking RegionSubstance PHuman leukocyte antigenBiologyCalcitonin gene-related peptideLinkage Disequilibriumchemistry.chemical_compoundInternal medicinemedicineHumansGenetic Predisposition to DiseaseDinucleotide RepeatsPromoter Regions GeneticNeprilysinGenetic Association StudiesGenetic associationNeurogenic inflammationPolymorphism GeneticGeneral NeurosciencefungiMiddle Agedmedicine.diseaseCRPS Pain NEP Association reflex sympathetic dystrophy syndrome type-i facilitated neurogenic inflammation nociceptive abnormalities alzheimers-disease neprilysin gene rat model enkephalinase prevalence dystoniaEndocrinologyComplex regional pain syndromechemistryCase-Control StudiesFemaleNeprilysinComplex Regional Pain Syndromes
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Ruptured angiomyolipoma of the kidney: a rare differential diagnosis of flank pain.

2017

Angiomyolipomas (AMLs) of the kidney are typically benign and rare, with an incidence of 2% of all renal masses [1]. They are associated with tuberous sclerosis in about 20% of cases. If ruptured, ...

AdultMalemedicine.medical_specialtyAngiomyolipomaFlank painUrologyAngiomyolipoma030232 urology & nephrologyUreteral stoneFlank PainDiagnosis Differential03 medical and health sciencesTuberous sclerosis0302 clinical medicinemedicineHumansKidneyRupture Spontaneousbusiness.industryIncidence (epidemiology)food and beveragesmedicine.diseaseKidney NeoplasmsSurgeryTomography x ray computedmedicine.anatomical_structureNephrology030220 oncology & carcinogenesisRadiologyDifferential diagnosisbusinessTomography X-Ray ComputedScandinavian journal of urology
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Sequence of a sea urchin hsp70 gene and its 5' flanking region.

1990

We report the nucleotide sequence of a 4470-bp fragment derived from a sea urchin genomic clone containing part of a heat-shock protein 70 (Hsp70)-encoding gene. This fragment, named hsp70 gene II, contains 1271 bp of the flanking region and 3299 bp of structural gene sequence interrupted by five introns and encoding the N-terminal 371 amino acids (aa) of the protein. The 5' flanking region contains a putative TATA element, two CCAAT boxes, four heat-shock consensus sequence elements (hse) and one consensus sequence for binding of Sp1. Remarkable homologies were observed for deduced aa sequence and intron-exon organization between hsp70 gene II and rat hsc73 gene.

5' flanking regionMolecular Sequence DataRestriction MappingBiologyExonSequence Homology Nucleic AcidConsensus SequenceGeneticsConsensus sequenceAnimalsAmino Acid SequencePromoter Regions GeneticGenePeptide sequenceHeat-Shock ProteinsGeneticsBase SequenceStructural geneNucleic acid sequenceGeneral MedicineExonsMolecular biologyIntronsGenesRegulatory sequenceSea UrchinsGene
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Transcription of human neuronal nitric oxide synthase mRNAs derived from different first exons is partly controlled by exon 1-specific promoter seque…

2006

AbstractThe human neuronal nitric oxide synthase (NOS1) gene is subject to extensive splicing. A total of 12 NOS1 mRNA species have been identified. They differ in their 5′ ends and are derived from 12 different first exons (termed exons 1a to 1l). Various cell lines whose NOS1 first exon expression patterns were representative of human brain, skin, and skeletal muscle were identified. These included A673 neuroepithelioma cells, SK-N-MC neuroblastoma cells, HaCaT keratinocyte-like cells, and C2C12 myocyte-like cells. In these cell lines, correlations were found between the exon 1 variants preferentially expressed and the promoter activities of their cognate 5′ flanking sequences. These data…

Transcription Genetic5' Flanking Region5' flanking regionReporter gene assaysSkeletal muscleNitric Oxide Synthase Type IBiologyKidneyHippocampusCell LineRT real-time PCRExonExon trappingGenes ReporterTestisGeneticsHumansRNA MessengerCloning MolecularLuciferasesPromoter Regions GeneticGeneSkinBinding SitesSplice site mutationReverse Transcriptase Polymerase Chain ReactionAlternative splicingGenetic VariationHeartExonsMolecular biologyAlternative SplicingRNA splicingCortexTandem exon duplicationProtein BindingTranscription FactorsGenomics
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High spatial resolution analysis of the iron oxidation state in silicate glasses using the electron probe

2018

The iron oxidation state in silicate melts is important for understanding their physical properties, although it is most often used to estimate the oxygen fugacity of magmatic systems. Often high spatial resolution analyses are required, yet the available techniques, such as μrXANES and μMössbauer, require synchrotron access. The flank method is an electron probe technique with the potential to measure Fe oxidation state at high spatial resolution but requires careful method development to reduce errors related to sample damage, especially for hydrous glasses. The intensity ratios derived from measurements on the flanks of FeLα and FeLβ X-rays (FeLβf/FeLαf) over a time interval (time-depend…

Dewey Decimal Classification::500 | Naturwissenschaften::540 | ChemieMaterials science010504 meteorology & atmospheric sciencesoxidationAnalytical chemistryreductionElectron010502 geochemistry & geophysics01 natural sciencesflank methodReduction (complexity)symbols.namesakeelectron beam damageGeochemistry and PetrologyOxidation stateElectron probe microanalysis (EPMA)High spatial resolutioniron (Fe) oxidation statesilicate glassSilicate glass0105 earth and related environmental sciencesGeophysicsddc:540Raman spectroscopysymbolsRaman spectroscopy
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