Search results for "Flow"

showing 10 items of 5185 documents

Selective downregulation of the MDR1 gene product in Caco-2 cells by stable transfection to prove its relevance in secretory drug transport.

2005

Considerable interest is focused on overcoming multidrug resistance (MDR) in cancer chemotherapy. The in vitro experiments to characterize P-glycoprotein's (P-gp) function and to decrease its effects have led to a variety of strategies such as addition of competitors or supplementation of the medium with oligonucleotides complementary to the 5'-end of the MDR1-mRNA. For the Caco-2 cell line, an in vitro model for absorption screening, expressing multiple transporters including P-gp, which pumps substances back into the apical solution, P-gp activity might mask other relevant transport proteins' activity. The objective of the present study was to construct a Caco-2 subline with reduced P-gp …

ATP Binding Cassette Transporter Subfamily BTime FactorsPharmaceutical ScienceDown-RegulationBiologyTransfectionPermeabilityPropanolaminesDownregulation and upregulationDrug DiscoveryHumansNorthern blotOligonucleotideReverse Transcriptase Polymerase Chain ReactionElectroporationBiological TransportTransfectionFlow CytometryMolecular biologyIn vitroTransport proteinClone CellsMutagenesis InsertionalVerapamilCell cultureMolecular MedicineCaco-2 CellsGenes MDRMolecular pharmaceutics
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"Figure 4.2.0" of "Measurement of the higher-order anisotropic flow coefficients for identified hadrons in Au$+$Au collisions at $\sqrt{s_{_{NN}}}$ =…

2021

Radial flow rapidity anisotropy $\rho_n$ in the blast-wave model fit to azimuthal anisotropy $v_2$ and invariant yields in Au+Au collisions at $\sqrt{s_{NN}} =$ 200 GeV.

AUAU --> CHRAGED XAstrophysics::High Energy Astrophysical PhenomenaNUCLEUS NUCLEUS --> CHARGED XFlow RapidityNuclear Experiment200
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"Figure 4.1" of "Measurement of the higher-order anisotropic flow coefficients for identified hadrons in Au$+$Au collisions at $\sqrt{s_{_{NN}}}$ = 2…

2021

Radially averaged flow rapidity $$ in the blast-wave model fit to azimuthal anisotropy and invariant yields in Au+Au collisions at $\sqrt{s_{NN}} =$ 200 GeV.

AUAU --> CHRAGED XAstrophysics::High Energy Astrophysical PhenomenaNUCLEUS NUCLEUS --> CHARGED XFlow RapidityNuclear Experiment200
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"Figure 4.2.3" of "Measurement of the higher-order anisotropic flow coefficients for identified hadrons in Au$+$Au collisions at $\sqrt{s_{_{NN}}}$ =…

2021

Radial flow rapidity anisotropy $\rho_n$ in the blast-wave model fit to azimuthal anisotropy $v_4\{\Psi_2\}$ and invariant yields in Au+Au collisions at $\sqrt{s_{NN}} =$ 200 GeV.

AUAU --> CHRAGED XAstrophysics::High Energy Astrophysical PhenomenaNUCLEUS NUCLEUS --> CHARGED XFlow RapidityNuclear Experiment200
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"Figure 4.2.2" of "Measurement of the higher-order anisotropic flow coefficients for identified hadrons in Au$+$Au collisions at $\sqrt{s_{_{NN}}}$ =…

2021

Radial flow rapidity anisotropy $\rho_n$ in the blast-wave model fit to azimuthal anisotropy $v_4$ and invariant yields in Au+Au collisions at $\sqrt{s_{NN}} =$ 200 GeV.

AUAU --> CHRAGED XAstrophysics::High Energy Astrophysical PhenomenaNUCLEUS NUCLEUS --> CHARGED XFlow RapidityNuclear Experiment200
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"Figure 4.2.1" of "Measurement of the higher-order anisotropic flow coefficients for identified hadrons in Au$+$Au collisions at $\sqrt{s_{_{NN}}}$ =…

2021

Radial flow rapidity anisotropy $\rho_n$ in the blast-wave model fit to azimuthal anisotropy $v_3$ and invariant yields in Au+Au collisions at $\sqrt{s_{NN}} =$ 200 GeV.

AUAU --> CHRAGED XAstrophysics::High Energy Astrophysical PhenomenaNUCLEUS NUCLEUS --> CHARGED XFlow RapidityNuclear Experiment200
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Chapter 3 patterns and thresholds of runoff generation and sediment transport on some Mediterranean hillslopes

2005

Abstract Runoff and sediment transport data obtained from hillslopes in two limestone areas in southeast Spain are analysed in order to define spatial and temporal thresholds for sediment movement at the patch scale under Mediterranean semiarid and subhumid climatological conditions. The data discussed in this paper include a 7-year series of runoff and sediment collection in open Gerlach plots. The 136 events are analysed in relation to characteristics of rainfall, soil and soil surface components. In both cases slopes behave as a patchwork of runoff and runon areas and the size of the runoff or runon patches being dependent on the climatological conditions. These control the hydrological …

Abiotic componentMediterranean climateHydrologyStreamflowEnvironmental scienceWEPPRunoff curve numberSaturation (chemistry)Surface runoffSediment transport
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Creatinine determination in urine samples by batchwise kinetic procedure and flow injection analysis using the Jaffé reaction: chemometric study

2001

The classical Jaffé reaction for the determination of creatinine in urine samples is tested. A comparative study of the main analytical characteristics focussed to minimize the bias error and improve the precision, for the batchwise and flow injection (FI) methods is realized. Also, the effect of the albumin concentration in the determination of creatinine has been studied. Different analytical signals were studied. Absorbance increments at different times permit to estimate the creatinine concentration free from bias error in urine by the batchwise method using the calibration graph obtained with creatinine standards and no measurement of the blank solution is needed. The lineal interval w…

AbsorbanceFlow injection analysisCreatininechemistry.chemical_compoundChromatographychemistryCalibration curveStandard additionCalibrationAnalytical chemistryUrineQuantitative analysis (chemistry)Analytical ChemistryTalanta
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Mechanical, thermal and acoustical characterizations of an insulating bio-based composite made from sunflower stalks particles and chitosan

2014

International audience; This study has for objective the determination of thermal, mechanical and acoustical properties of insulating bio-based composite made with chitosan and sunflower's stalks particles. An experimental design was established to find the size grading of particles, the ratio chitosan/sunflower particles and the stress of compaction influencing the thermal and mechanical properties. Composites with a thermal conductivity $(\kappa)$ of 0.056 W/m/K, a maximum stress $(\sigma_{\text{max}})$ of 2 MPa and an acoustic coefficient of absorption $(\alpha)$ of 0.2 were obtained with a ratio of chitosan of 4.3% (w/w) and a size grading of particles higher to 3 mm. These mechanical a…

Absorption (acoustics)Materials science020209 energyComposite numberCompactionYoung's modulus02 engineering and technologyChitosanStress (mechanics)[SPI]Engineering Sciences [physics]chemistry.chemical_compoundsymbols.namesakeThermal conductivityThermal0202 electrical engineering electronic engineering information engineeringYoung modulus[INFO]Computer Science [cs]Composite material[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]Chitosan[ SPI.ACOU ] Engineering Sciences [physics]/Acoustics [physics.class-ph]021001 nanoscience & nanotechnologySunflowerBio-based compositechemistryThermal conductivitysymbols0210 nano-technologyAgronomy and Crop ScienceIndustrial Crops and Products
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On the variations of acoustic absorption peak with particle velocity in micro-perforated panels at high level of excitation.

2010

The acoustic behavior of micro-perforated panels (MPP) is studied theoretically and experimentally at high level of pressure excitation. A model based on Forcheimer's regime of flow velocity in the perforations is proposed. This model is valid at relatively high Reynolds numbers and low Mach numbers. The experimental method consists in measuring the acoustical pressure at three different positions in an impedance tube, the two measurement positions usually considered in an impedance tube and one measurement in the vicinity of the rear surface of the MPP. The impedance tube is equipped with a pressure driver instead of the usual loudspeaker and capable of delivering a high sound pressure lev…

Absorption (acoustics)Materials scienceAcoustics and UltrasonicsAcoustics[ PHYS.COND.CM-MS ] Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]FOS: Physical sciencesPhysics - Classical PhysicsPolypropylenes01 natural sciences010305 fluids & plasmasAbsorption[SPI]Engineering Sciences [physics]symbols.namesakeMotionArts and Humanities (miscellaneous)0103 physical sciencesPressureParticle velocitySound pressure010301 acoustics[ PHYS.MECA.ACOU ] Physics [physics]/Mechanics [physics]/Acoustics [physics.class-ph][SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph][ SPI.ACOU ] Engineering Sciences [physics]/Acoustics [physics.class-ph]Construction MaterialsAirFluid Dynamics (physics.flu-dyn)Classical Physics (physics.class-ph)Reynolds numberPhysics - Fluid DynamicsAcousticsModels TheoreticalSound intensity[PHYS.MECA.ACOU]Physics [physics]/Mechanics [physics]/Acoustics [physics.class-ph]Mach numberFlow velocityNonlinear DynamicsSteelFacility Design and Construction[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]symbolsLinear ModelsAcoustic impedanceNoisePorosityThe Journal of the Acoustical Society of America
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