Search results for "Forensic"

showing 10 items of 1701 documents

Electrophysiological Investigations of Shape and Reproducibility of Oropharyngeal Swallowing: Interaction with Bolus Volume and Age

2015

Electrophysiological assessment provides valuable information on physiological and pathophysiological characteristics of human swallowing. Here, new electrophysiological measures for the evaluation of oropharyngeal swallowing were assessed: (1) the activation pattern of the submental/suprahyoid EMG activity (SHEMG); (2) the reproducibility of the oral and pharyngeal phases of swallowing, by calculating the similarity index (SI) of the SHEMG (SI-SHEMG) and of the laryngeal-pharyngeal mechanogram (SI-LPM) during repeated swallows; and (3) kinesiological measures related to the LPM. An electrophysiological-mechanical method for measuring the activation pattern of the SHEMG, the SI-SHEMG, and t…

AdultMalemedicine.medical_specialtyBolus volumeOropharynxElectromyographySpeech and HearingYoung AdultAgeSwallowingMedicineHumansYoung adultAgedAged 80 and overReproducibilitymedicine.diagnostic_testbusiness.industryElectromyographyOtorhinolaryngology2734 Pathology and Forensic MedicineGastroenterologyReproducibility of ResultsDysphagiaMiddle AgedSwallowingDysphagiaReproducibilityDeglutitionAge; Bolus volume; Dysphagia; Electromyography; Reproducibility; Swallowing; Otorhinolaryngology2734 Pathology and Forensic Medicine; Gastroenterology; 3616ElectrophysiologyOtorhinolaryngologyOtorhinolaryngologyAnesthesiaSettore MED/26 - NeurologiaFemaleBolus (digestion)medicine.symptomLaryngeal Muscles3616businessDeglutition Disorders
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Post-traumatic lethal carotid-cavernous fistula.

2006

The authors report about an unexpected death by traumatic lesion of the internal carotid artery in a 30-year-old man who had fallen two metres. The man suffered a fracture of the left maxillary sinus and a fracture of the right orbit with bilateral haemorrhage of the maxillary sinus. Surgical treatment was performed with favorable outcome. Clinically, there were no neurological symptoms but about 60 days after his accident, the man died from uncontrolled epistaxis. He was submitted to the autopsy that show a linear fracture in the left side of the turcic sella and lesion of the left internal carotid artery with carotid-cavernous fistula.

AdultMalemedicine.medical_specialtyCarotid-cavernous fistulaMaxillary sinusFistulaAutopsyHemorrhageTraumaUnexpected deathMaxillary FracturesPathology and Forensic MedicineLesionCarotid-Cavernous Sinus FistulaSettore MED/43 - Medicina Legalemedicine.arterymedicineHumansSella TurcicaCarotid-cavernous fistulaOrbital FracturesArterial dissectionSkull Fracturesbusiness.industryGeneral MedicineUnexpected deathMaxillary Sinusmedicine.diseaseSurgerymedicine.anatomical_structureEpistaxisAccidental FallsRadiologyArterial dissectionInternal carotid arterymedicine.symptombusinessCarotid Artery InjuriesLawCarotid Artery InternalJournal of forensic and legal medicine
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Methionine synthase reductase (MTRR) A66G polymorphism is not related to plasma homocysteine concentration and the risk for vascular disease.

2009

Epidemiological evidence has revealed that hyperhomocysteinemia increases the risk for vascular disease. Methionine Synthase Reductase (MTRR) is one of several key enzymes in the homocysteine metabolic pathway and its mutant forms have been implicated in abnormal homocysteine accumulation. In this study, we determined total plasma homocysteine levels and MTRR A66G polymorphism in 114 patients with vascular disease: 58 patients with deep-vein thrombosis, 56 patients with arterial thrombosis, and 95 healthy subjects from the Sicilian population. Our data confirmed that, as already reported, moderately elevated t-Hcy levels are correlated with an increased risk of vascular disease. In our stud…

AdultMalemedicine.medical_specialtyHyperhomocysteinemiaMethyltransferaseHomocysteineClinical BiochemistryPopulationMethionine synthase reductase homocysteinePolymorphism Single NucleotidePathology and Forensic Medicinechemistry.chemical_compoundInternal medicineMedicineHumansGenetic Predisposition to DiseaseVascular DiseaseseducationMolecular BiologyHomocysteineAgededucation.field_of_studybiologybusiness.industryVascular disease(Methionine synthase) reductaseMiddle Agedmedicine.diseaseMTRRFerredoxin-NADP ReductaseVenous thrombosisEndocrinologyBiochemistrychemistryCase-Control Studiesbiology.proteinFemalebusinessExperimental and molecular pathology
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Enhancing the efficacy of treatment for temporomandibular patients with muscular diagnosis through cognitive-behavioral intervention, including hypno…

2011

Objective This study evaluated the efficacy of a cognitive-behavioral therapy (CBT), including hypnosis, in patients with temporomandibular disorders (TMDs) with muscular diagnosis. Study Design Seventy-two patients (65 women and 7 men with an average age of 39 years) were selected according to the Research Diagnostic Criteria for TMD, and assigned to the experimental group (n = 41), receiving the 6-session CBT program, and the control group (n = 31). All patients received conservative standard treatment for TMD. The assessment included pain variables and psychologic distress. Results There were significant differences between the groups, the experimental group showing a higher improvement …

AdultMalemedicine.medical_specialtyHypnosismedicine.medical_treatmentResearch Diagnostic CriteriaRelaxation TherapyPathology and Forensic Medicinelaw.inventionYoung AdultRandomized controlled trialFacial PainlawHumansMedicineRadiology Nuclear Medicine and imagingDentistry (miscellaneous)Physical Therapy ModalitiesAgedChi-Square DistributionCognitive Behavioral Therapybusiness.industryStandard treatmentChronic painMiddle AgedTemporomandibular Joint Dysfunction Syndromemedicine.diseaseCombined Modality TherapyCognitive behavioral therapyTreatment OutcomeMultivariate AnalysisPhysical therapyCognitive therapyFemaleSurgeryChronic PainOral SurgerybusinessChi-squared distributionHypnosisOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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Identification of unknown dead bodies by X-ray image comparison of the skull using the X-ray simulation program FoXSIS.

2001

The aim of the study was to improve the objectivity of X-ray image comparison for the identification of unknown dead individuals. CT-data were collected for 30 macerated skulls. An already presented computer program which uses CT data to establish virtual X-ray images was used to obtain X-rays with different beam angulations simulating rotation, dorsal flexion, and ventral flexion. Specific parameters were measured on the simulated images. The frontal sinus reveals the highest variability not only between the individual skulls but also within an individual skull in different positions. The most consistent parameters with respect to different positions were the skull breadth, the biorbital b…

AdultMalemedicine.medical_specialtyImage processingPathology and Forensic MedicineBlind studymedicineImage Processing Computer-AssistedHumansComputer SimulationMathematicsbusiness.industrySkullPattern recognitionSurgeryIdentification (information)Skullmedicine.anatomical_structureX ray imageForensic radiologyForensic AnthropologyFrontal SinusFemaleArtificial intelligenceTomographybusinessTomography X-Ray ComputedLawRotation (mathematics)SoftwareForensic science international
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Hanging disguised as bondage: accidental or suicidal death?

2020

The concept of autoerotic asphyxiation refers to the use of devices or substances intended to enhance one's arousal by inducing cerebral hypoxia, which can involuntarily lead to death. Although in most cases death occurs accidentally, it is nonetheless true that the same devices might be used by the practitioners in order to attempt suicide. The case of a 34-year-old practitioner of autoerotic asphyxiation found dead in his apartment with bondage-like ligatures and masking is reported here. The case raised some issues concerning the accidental or suicidal nature of the act. The aspects taken into account in the management of the case are discussed, along with a compared approach to the data…

AdultMalemedicine.medical_specialtyInjury controlBondagePoison control01 natural sciencesSuicide preventionOccupational safety and healthPathology and Forensic MedicineNeck InjuriesAsphyxia03 medical and health sciencesFatal Outcome0302 clinical medicineSettore MED/43 - Medicina LegaleInjury preventionmedicineHumans030216 legal & forensic medicineHypoxiaPsychiatryParaphilic Disorders010401 analytical chemistryHyoid BoneHuman factors and ergonomicsAutoerotic asphyxiationGeneral Medicine0104 chemical sciencesHangingAccidents HomeAccidentalAutoerotic deathBlood Alcohol ContentPsychologyAttempt suicideForensic Science, Medicine and Pathology
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Bone Marrow Findings in Multicentric Castleman Disease in HIV-negative Patients

2007

Because bone marrow histology in multicentric Castleman disease in human immunodeficiency virus-negative patients is not well reported, we investigated sequential bone marrow biopsies of 3 affected human immunodeficiency virus-negative patients, of which one was human herpes virus 8 (HHV8)-positive. The histologic evaluation of the bone marrow revealed lymphoid follicles with regressed germinal centers in 1 patient. Another patient showed tumorlike but bland polyclonal plasmacytosis with large perivascular plasma cell clusters. The HHV8-positive patient revealed interstitial HHV8-positive cells accompanied by a mild plasmacytosis. The atypical lymphoid follicles could be regarded as a bone …

AdultMalemedicine.medical_specialtyPathologyBone Marrow CellsPlasma cellPathology and Forensic MedicineImmune systemBone MarrowHIV SeronegativityImmunopathologymedicineHumansAntigens ViralAgedbusiness.industryCastleman DiseaseCastleman diseasePlasmacytosisvirus diseasesGerminal centerAnatomical pathologyHerpesviridae InfectionsMiddle AgedGerminal Centermedicine.diseasemedicine.anatomical_structureDNA ViralHerpesvirus 8 HumanImmunologyFemaleSurgeryLymph NodesBone marrowAnatomybusinessAmerican Journal of Surgical Pathology
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Does Cytokeratin7/20 immunoreactivity help to distinguish Barrett's esophagus from gastric intestinal metaplasia? Results of a prospective study of 7…

2005

Barrett's esophagus is a recognized risk factor for the development of esophageal dysplasia and carcinoma. Unfortunately, gastric incomplete intestinal metaplasia arising in Short Segment Barrett's esophagus can be indistinguishable histologically on hematoxylin/eosin stains. Distinct patterns of CK 7 and CK 20 immunohistochemical expression have been demonstrated to be both highly sensitive and specific for Barrett's esophagus, but have not been found in gastric metaplasia. The aim of our study was to test whether immunostaining with CK 7/20 helps to distinguish between Barrett's epithelium and gastric incomplete metaplasia. Cases of long segment Barrett's esophagus, short segment Barrett'…

AdultMalemedicine.medical_specialtyPathologyH&E stainKeratin-20digestive systemGastroenterologyPathology and Forensic MedicineDiagnosis DifferentialBarrett EsophagusIntermediate Filament ProteinsPredictive Value of TestsInternal medicineMetaplasiaBiomarkers TumorPyloric AntrummedicineCarcinomaHumansProspective StudiesEsophagusneoplasmsMetaplasiabusiness.industryKeratin 20Keratin-7Intestinal metaplasiaCardiaCell BiologyMiddle Agedmedicine.diseasedigestive system diseasessurgical procedures operativemedicine.anatomical_structureBarrett's esophagusKeratin 7KeratinsFemalemedicine.symptombusinessPathology - Research and Practice
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Multiple Peptide Hormone Producing Adenocarcinoma of Lung with Neurotensin and CRF-like Immunoreactivity

1988

Summary A pulmonary cancer of a 43 year-old-man was classified according to WHO-criteria as a poorly differentiated adenocarcinoma because of demonstration of mucinous substances in tumor cells and in rarely occurring acinar lumina. Immunohistochemical reactivity for several peptide hormones was detected in the predominant solid parts of the carcinoma. In many tumor cells an immunoreactivity to neurotensin, bombesin and — according to the elevated serum levels — to ACTH, CRF and calcitonin was found. Therefore the present lung cancer must be defined as a combined carcinoma composed of mucous producing and endocrine cell types. Because peptide hormone production is not restricted to the clas…

AdultMalemedicine.medical_specialtyPathologyLung NeoplasmsCorticotropin-Releasing HormoneEnteroendocrine cellAdenocarcinomaPeptide hormoneBiologyPathology and Forensic Medicinechemistry.chemical_compoundInternal medicinemedicineCarcinomaHumansLung cancerNeurotensinBombesinCell Biologymedicine.diseaseImmunohistochemistryEndocrinologychemistryCalcitoninHormones EctopicAdenocarcinomahormones hormone substitutes and hormone antagonistsNeurotensinPathology - Research and Practice
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Sudden death due to cardiac sarcoidosis in a case of suspected homicide

1993

In a case of suspected homicide death due to natural causes — cardiac death (SCD) — was found at autopsy. Despite an extensive replacement of myocardial tissue by sarcoid granulomata there was no history of cardiac dysfunction or preceding symptoms. The transmurally infiltrating granulomata and the concomitant fibrosis were predominantly confluent. They occupied vast areas within the interventricular septum and the adjacent posterior wall of the left ventricle. The only other organs involved were mediastinal lymph nodes, which appeared macroscopically normal.

AdultMalemedicine.medical_specialtyPathologySarcoidosisAutopsySudden deathPathology and Forensic MedicineDiagnosis DifferentialHomicideFibrosishemic and lymphatic diseasesInternal medicineHumansMedicineInterventricular septumbusiness.industryMyocardiummedicine.diseaseDeath Sudden Cardiacmedicine.anatomical_structureVentricleConcomitantCardiologyLymphCardiomyopathiesHomicidebusinessEndocardiumInternational Journal of Legal Medicine
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