Search results for "Format"
showing 10 items of 24643 documents
ITIL-viitekehyksen mukaisen ongelmanhallintaprosessin kriittiset menestystekijät : tapaustutkimus IT-palveluorganisaatiossa
2016
Tutkielman tarkoituksena on tutkia Information Technology Infrastructure Library (ITIL) -viitekehyksen mukaisen ongelmanhallintaprosessin kriittisiä menestystekijöitä. ITIL-viitekehys on laajasti käytetty kokoelma parhaita käytäntöjä IT-palvelunhallintaan, joita voidaan soveltaa kuhunkin organisaatioon sopivaksi tarpeiden mukaan. Ongelmanhallintaprosessi on yksi palvelunhallinnan prosesseista, jolla on tärkeä rooli insidenttien eli tapahtumien juurisyiden tutkinnassa. Ongelmalla tarkoitetaan yhden tai useamman tapahtuman tarkempaa juurisyytä. Ongelmanhallinnan keskeinen tehtävä on juurisyiden löytäminen ja poistaminen. Kirjallisuuskatsauksessa perehdytään ITIL-viitekehykseen ja ongelmanhall…
"Tiedehän on ensisijaisesti tiedonhankintajärjestelmä"
2018
Jokapäiväisessä työssä käytämme omaan työhömme liittyviä käsitteitä usein epätäsmällisesti. Akateemisessa kontekstissa tilannetta mutkistaa se, että tieteellinen työskentely perustuu käsitteille ja niiden välisille suhteille. Tässä artikkelissa keskustelen muutamista tiedonhankinnan opetukseen liittyvistä keskeisistä käsitteistä, kuten otsikossa mainittu tiedonhankinta, sekä niiden tulkinnoista. Lisäksi pohdin tulkintoihin liittyviä etuja ja haittoja opiskelijoiden kanssa yhteistyössä tehdyn opetuksen kehittämistyön näkökulmasta.
Building Situational Awareness of GDPR
2023
Because previous academic research does not comment sufficiently on how the relevant content of the European Union (EU) General Data Protection Regulation (GDPR has been properly communicated to the organisations, or how the situational awareness (SA) of GDPR has been built in the organisations, this qualitative empirical research was regarded as a valuable approach for gathering authentic research material on the practical bases of this phenomena. The aim of this empirical case study (CS) is to develop a picture of what processes organisations use to build SA of the GDPR requirements. To guide the CS, we asked how the SA for decision-making was constructed and how it was perceived in organ…
Immobilization of proteins in silica gel: Biochemical and biophysical properties
2015
The development of silica-based sol-gel techniques compatible with the retention of protein structure and function started more than 20 years ago, mainly for the design of biotechnological devices or biomedical applications. Silica gels are optically transparent, exhibit good mechanical stability, are manufactured with different geometries, and are easily separated from the reaction media. Biomolecules encapsulated in silica gel normally retain their structural and functional properties, are stabilized with respect to chemical and physical insults, and can sometimes exhibit enhanced activity in comparison to the soluble form. This review briefly describes the chemistry of protein encapsulat…
Investigating protein structure and dynamics through wide-angle X-ray solution scattering
2016
Wide-angle X-ray scattering (WAXS) is a powerful tool that can be used to gain information on the structure and dynamics of proteins and other biomolecules in solution. Improved methods for the calculation of WAXS patterns from available or putative protein models allow to better exploit the structural information contained in the experimental data. These methods, together with recent applications of static and time-resolved WAXS, are briefly reviewed.
Comparative proteomics of breast cancer surgical tissues
2009
Proteomics in antitumor research
2006
Proteins are the molecular players of fine-tuned regulatory pathways that underlie the behavior of any cell type. Derangement of this wide protein circuitry has a profound effect on cell life and ultimately contributes to the development of diseases such as cancer. New proteomic technologies are rapidly evolving to define and characterize the nodes of this altered protein network, both inside and outside cancer cells. Hopefully, these technologies will become user-friendly laboratory tools to improve cancer management from early detection to the development of rational and patient-tailored therapeutic strategies.
Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology (LETSGO study): A study protocol for a multicentre longitudinal interve…
2021
IntroductionThe number of gynaecological cancer survivors is increasing and there is a need for a more sustainable model of follow-up care. Today’s follow-up model is time-consuming and patients have reported unmet needs regarding information about their cancer and strategies for managing the consequences of treatment. The main aim of this study is to assess health-related empowerment—in terms of patient education, psychosocial support, and promotion of physical activity—in a new follow-up model by comparing it to standard follow-up in a quasi-randomised study involving intervention hospitals and control hospitals.Methods and analysisAt the intervention hospitals, patients will be stratifie…
Proton shape fluctuation and its relation to DIS
2018
We review the recent progress in extracting the proton fluctuating substructure by studying exclusive processes at HERA, and the applications of these developments in the interpretation of the LHC heavy ion data. The possibilities to extract the proton geometry directly from the LHC high-multiplicity proton-nucleus and proton-proton collision data is also discussed. peerReviewed
Scheduling under the network of temporo-spatial proximity relationships
2017
We discuss and introduce to the schedulingeld a novel, qualitative optimization model - scheduling under the network of temporo-spatial proximity relationships.We introduce a half perimeter proximity measure as an objective of scheduling.We present and evaluate an incremental Sequence Pair neighborhood evaluation algorithm, applicable to both scheduling and rectangle packing problems in VLSI industry. In this paper, we discuss and introduce to the scheduling field a novel optimization objective - half perimeter proximity measure in scheduling under the network of temporo-spatial proximity relationships. The presented approach enables to qualitatively express various reasons of scheduling ce…