Search results for "Fracture"

showing 10 items of 873 documents

Incidence rates of fragility hip fracture in middle-aged and elderly men and women in southern Norway.

2011

Background Hip fracture contributes to increased morbidity and mortality in the elderly population. As the average age of the population is increasing, the burden of hip fracture on the health-care system is a growing challenge. The highest incidence of hip fracture worldwide has been reported from Scandinavia in fact from Oslo the capital of Norway. During the last decades, efforts have been undertaken to reduce hip fracture risk. Objective To study the incidence of fragility hip fracture in southern Norway. Design A validated retrospective epidemiological study. Setting Population-based study. Subjects All patients with fragility hip fractures aged 50 years or older in 2004 and 2005 in so…

MaleAgingmedicine.medical_specialtyFrail ElderlyPopulationFragilityAge groupsEpidemiologyMedicineHumanseducationAge specific incidenceAgedRetrospective StudiesAged 80 and overHip fractureeducation.field_of_studyBone Density Conservation Agentsbusiness.industryHip FracturesNorwayIncidence (epidemiology)IncidenceRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseSurgeryOsteoporosisFemaleSeasonsGeriatrics and GerontologybusinessDemographyAge and ageing
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Retrospective evaluation of persistence in osteoporosis therapy with oral bisphosphonates in Italy: the TOBI study

2019

The patients’ persistence with osteoporosis treatments is low. This retrospective, multicenter survey showed that almost 30% of osteoporotic patients discontinued the treatment within the first 6 months and that those taking drinkable bisphosphonates were less likely to interrupt the therapy; instead, the use of generic bisphosphonates was associated to a more precocious interruption. Purpose: Low persistence with osteoporosis medications is associated with higher fracture risk. This study aimed to assess the persistence to treatment with oral bisphosphonates among Italian osteoporotic patients under treatment for at least 6 months and to evaluate whether the different oral formulations of …

MaleAgingmedicine.medical_specialtyGeneric drugmedicine.medical_treatmentOsteoporosisDrinkable bisphosphonates; Generic drug; Oral bisphosphonates; Osteoporosis; PersistenceAdministration OralPersistence (computer science)Medication AdherencePersistence03 medical and health sciencesFractures Bone0302 clinical medicineInternal medicineGeneric drugmedicineHumansDrinkable bisphosphonatesGeneric drugOral bisphosphonatesOsteoporosisPersistence030212 general & internal medicineMedical prescriptionAdverse effectAgedRetrospective StudiesOral bisphosphonatesBone Density Conservation AgentsDiphosphonatesbusiness.industryOral bisphosphonatesSettore MED/34 - Medicina Fisica E RiabilitativaBisphosphonateMiddle Agedmedicine.diseaseDiscontinuationLogistic ModelsItalyCase-Control StudiesOsteoporosisFemaleGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryOsteoporotic FracturesDrinkable bisphosphonates
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Risk factors for pelvic insufficiency fractures and outcome after conservative therapy

2016

Abstract Purpose The prevalence of osteoporosis has continuously increased over the past decades and it is set to increase substantially as life expectancy rises steadily. Fragility or osteoporotic fractures of the pelvis often occur after low energy falls e.g. from standing, however, some patients present with assumed insufficiency fractures of the pelvis without a previous trauma. Osteoporotic fractures impose a tremendous economic burden and these fractures deserve attention as they lead to a decrease in mobility with an increase in dependency and are associated with a high rate of mortality. To date, little is known about potential risk factors for pelvic insufficiency fractures. Furthe…

MaleAgingmedicine.medical_specialtyHealth (social science)Osteoporosis030209 endocrinology & metabolismConservative Treatmentvitamin D deficiency03 medical and health sciencessymbols.namesake0302 clinical medicineRisk FactorsGermanyPrevalenceInsufficiency fractureHumansMedicineMedical historyMobility LimitationPelvic BonesFisher's exact testPelvisAged030222 orthopedicsbusiness.industryMortality rateVitamin D Deficiencymedicine.diseaseSurgerymedicine.anatomical_structurePelvic fracturesymbolsFemaleGeriatrics and GerontologybusinessGerontologyOsteoporotic FracturesArchives of Gerontology and Geriatrics
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Motor speed and lower extremity strength as predictors of fall-related bone fractures in elderly individuals.

2006

Background and aims: The purpose of this prospective population-based study was to examine the combined effects of motor speed and knee extension strength on risk of fall-related bone fractures in elderly individuals over a 10-year period. Methods: Participants were 307 men and women aged 75 or 80 years at baseline, who visited the research laboratory at the University of Jyvaskyla, Finland. Multi-choice motor speed tests and maximal isometric knee extension strength tests were carried out at baseline. Information on fractures was collected from hospital and health center records. The presence of impairment was defined as a score in the lowest tertile of sex- and age-stratified distribution…

MaleAgingmedicine.medical_specialtyKnee JointPopulationPoison controlMotor ActivityFractures BonePredictive Value of TestsRisk FactorsMedicineHumansMuscle StrengthProspective StudieseducationProspective cohort studyExerciseAgedProportional Hazards ModelsBone mineralAged 80 and overeducation.field_of_studybusiness.industryProportional hazards modelIncidenceConfidence intervalPredictive value of testsRelative riskPhysical therapyAccidental FallsFemaleGeriatrics and GerontologybusinessPsychomotor PerformanceAging clinical and experimental research
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New intramedullary locking nail for olecranon fracture fixation--an in vitro biomechanical comparison with tension band wiring.

2010

The aim of this study was to determine the difference in displacement of a newly designed intramedullary olecranon fracture fixation device compared with multifilament tension band wiring after 4 cycles and 300 cycles of dynamic continuous loading.In eight pairs of fresh-frozen cadaver ulnae, oblique olecranon fractures were created and stabilized using either newly designed intramedullary olecranon nail or multifilament tension band wiring. The specimens were then subjected to continuous dynamic loading (from 25 N to 200 N) using matched pairs of cadaveric upper extremities. The Wilcoxon test was used to determine statistical differences of the displacement in the fracture gap.After 4 cycl…

MaleBone NailsCritical Care and Intensive Care MedicineProsthesis Designlaw.inventionIntramedullary rodFixation (surgical)lawFracture fixationElbow JointmedicineHumansDisplacement (orthopedic surgery)Olecranon ProcessRange of Motion ArticularBone WiresAgedOrthodonticsAged 80 and overbusiness.industryTension band wiringMiddle Agedmedicine.diseaseUlna FracturesBiomechanical PhenomenaFracture Fixation Intramedullarymedicine.anatomical_structureOlecranon fractureNail (anatomy)SurgeryFemaleStress MechanicalbusinessElbow InjuriesBone WiresThe Journal of trauma
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Volar Fixed-Angle Plating of Distal Radius Fractures

2011

The purpose of this biomechanical study was to determine whether a multidirectional fixed-angle plate with locking screws or with locking pegs in the distal fragment would optimize fixation of Orthopaedic Trauma Association (OTA) type A3 distal radius fractures.Eight pairs of fresh-frozen human distal radii were used. Extra-articular distal radius fractures were created and stabilized with a multidirectional volar fixed-angle plate. The radii were randomized into 2 matched-paired groups. The distal fragment in Group I was stabilized with 7 locking screws. The distal fragment in Group II was fixed with 7 locking pegs. The proximal fragment in both groups was fixed with 3 screws. The specimen…

MaleBone ScrewsBone NailsBiomechanical PhenomenaFracture Fixation InternalFixation (surgical)Fixed angleCadaverFracture fixationBone plateCadaverHumansMedicineOrthopedics and Sports MedicineAgedMechanical PhenomenaAged 80 and overOrthodonticsbusiness.industryGeneral MedicineRadiusMiddle AgedBiomechanical PhenomenaProsthesis FailureEquipment Failure AnalysisFemaleSurgeryRadius FracturesbusinessCadaveric spasmBone PlatesJournal of Orthopaedic Trauma
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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

2012

Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 genome-wide association studies and 32,961 individuals of European and east Asian ancestry. We tested the top BMD-associated markers for replication in 50,933 independent subjects and for association with risk of low-trauma fracture in 31,016 individuals with a history of fracture (cases) and 102,444 controls. We identified 56 loci (32 new) associated with BMD at genome-wide significance (P < 5 × 10 -8). Several of these factors cluster within the RANK-RANKL-OPG, mesenchymal stem cell differentiation, endochondral…

MaleBone densityOsteoporosisGenome-wide association studyMitochondrial Membrane Transport ProteinsBone densitometryFractures Bone0302 clinical medicineBone DensityRisk FactorsFemurGeneticsBone mineral0303 health scienceseducation.field_of_studyExtracellular Matrix ProteinsLumbar VertebraeFemur Neckta3141medicine.anatomical_structureLow Density Lipoprotein Receptor-Related Protein-5/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingIntercellular Signaling Peptides and ProteinsFemaleGensmusculoskeletal diseases/dk/atira/pure/subjectarea/asjc/1300/1311GenotypePopulationEuropean Continental Ancestry GroupQuantitative Trait Loci030209 endocrinology & metabolismVèrtebres lumbarsBiologyFèmurPolymorphism Single NucleotideArticleWhite People03 medical and health sciencesSDG 3 - Good Health and Well-beingDensitometria òssiaGeneticsmedicineHumansGenetic Predisposition to Diseaseeducation030304 developmental biologyFemoral neckGenetic associationGlycoproteinsGene Expression ProfilingComputational BiologySpectrinta3121medicine.diseasePhosphoproteinsGenesOsteoporosisMesenchymal stem cell differentiationHuman medicineFracturesGenome-Wide Association Study
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Occupational group, educational level, marital status and deleterious habits among individuals with maxillofacial fractures: retrospective study

2018

Background To investigate the occupational profile, educational level, marital status and deleterious habits to the health of patients with maxillofacial fractures of a population of northeastern Brazil. Material and Methods A retrospective study of patients records admitted to the Division of Oral and Maxillofacial Surgery at the Walter Cantídio University Hospital (Fortaleza, Brazil) who sustained maxillofacial fractures was conducted in the period between 2006 and 2015. Results A total of 338 patients rendered 355 fractures. Males were the most affected (p<0.001), with prevalence in the third decade of life (p<0.001). There was a predominance of motorcycle accidents (p<0.001), home worke…

MaleCross-sectional studyEstudos EpidemiológicosFractures BoneHabits0302 clinical medicineRisk FactorsEpidemiologyPrevalence030212 general & internal medicineYoung adultChildeducation.field_of_studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Child PreschoolUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgeryMarital statusEducational StatusFemaleAdultmedicine.medical_specialtyOccupational groupAdolescentPopulationFacial Bones03 medical and health sciencesYoung AdultmedicineHumansOccupationseducationGeneral DentistryRetrospective StudiesOral Medicine and PathologyMarital Statusbusiness.industryResearchOssos FaciaisInfantRetrospective cohort study030206 dentistryEpidemiologic StudiesCross-Sectional StudiesOtorhinolaryngologySurgeryMaxillofacial InjuriesbusinessDemography
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Utility of post mortem computed tomography in clivus fracture diagnosis. Case illustration and literature review

2017

Clivus fractures are usually associated with head blunt trauma due to traffic accident and falls. A 23 - year-old man died immediately after a smash-up while he was stopping on his motorcycle. Post-mortem Computed tomography (PMCT), performed before autopsy, revealed a complex basilar skull base fractures associated with brainstem and cranio-vertebral junction injuries, improving the diagnostic performance of conventional autopsy. Imaging data were re-assessable and PMCT offers the possibility to perform multiplanar and volume rendered reconstructions, increasing forensic medicine knowledge related to traumatic injuries.

MaleForensic pathologymedicine.medical_specialtyPost-mortem CT - Forensic pathology - Clivus fracture - Traffic accident - Brainstem laceration -Cervical spineClivus fractureAutopsyPathology and Forensic MedicineYoung Adult03 medical and health sciences0302 clinical medicineSettore MED/43 - Medicina LegaleClivusmedicineHumans030216 legal & forensic medicinePost mortem computed tomographyForensic PathologySkull Fracturesbusiness.industryTraffic accidentAccidents TrafficSurgeryDeathIssues ethics and legal aspectsSkullmedicine.anatomical_structureBlunt traumaAutopsyRadiologyTomography X-Ray Computedbusiness030217 neurology & neurosurgeryBrain StemLegal Medicine
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Do we really need new medical information about the Turin Shroud?

2014

Abstract Image processing of the Turin Shroud (TS) shows that the Man represented in it has undergone an under glenoidal dislocation of the humerus on the right side and lowering of the shoulder, and has a flattened hand and enophthalmos; conditions that have not been described before, despite several studies on the subject. These injuries indicate that the Man suffered a violent blunt trauma to the neck, chest and shoulder from behind, causing neuromuscular damage and lesions of the entire brachial plexus. The posture of the left claw-hand is indicative of an injury of the lower brachial plexus, as is the crossing of the hands on the pubis, not above the pubis as it would normally be, and …

MaleForensic pathologymedicine.medical_specialtyThoracic InjuriesFamous PersonsContusionsPoison controlWounds PenetratingViolenceWounds NonpenetratingChristianityFractures BoneBluntmedicineSettore MED/33 - Malattie Apparato LocomotoreHumansBrachial PlexusHumerusForensic PathologyHistory AncientGeneral Environmental ScienceHemothoraxbusiness.industryEnophthalmosLung InjuryHemothoraxmedicine.diseaseTurin Shroud Trauma to the shoulder neck and chest Humerus dislocation Enophthalmos HemothoraxSurgerybody regionsmedicine.anatomical_structureLiteratureBlunt traumaForensic AnthropologyWounds and InjuriesGeneral Earth and Planetary SciencesShoulder Injuriesmedicine.symptomHomicidebusinessBrachial plexus
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