Search results for "G1"

showing 10 items of 717 documents

Pricing of Forwards and Options in a Multivariate Non-Gaussian Stochastic Volatility Model for Energy Markets

2013

In Benth and Vos (2013) we introduced a multivariate spot price model with stochastic volatility for energy markets which captures characteristic features, such as price spikes, mean reversion, stochastic volatility, and inverse leverage effect as well as dependencies between commodities. In this paper we derive the forward price dynamics based on our multivariate spot price model, providing a very flexible structure for the forward curves, including contango, backwardation, and hump shape. Moreover, a Fourier transform-based method to price options on the forward is described.

TheoryofComputation_MISCELLANEOUSspread optionStatistics and Probability15A04Computer Science::Computer Science and Game TheoryFinancial economicsNormal backwardationImplied volatility01 natural sciences010104 statistics & probabilityEnergy marketVolatility swap0502 economics and businessEconometricsForward volatilitystochastic volatility0101 mathematicsMathematics050208 financeStochastic volatilityApplied Mathematics05 social sciencesContangosubordinatorforward pricing91G20Forward priceVolatility smile60H3060G1060G51Advances in Applied Probability
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Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb

2003

Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb

Time FactorsLeupeptinsApoptosisRetinoblastoma ProteinAntioxidantsAmino Acid Chloromethyl KetonesMembrane Potentialschemistry.chemical_compoundSettore BIO/10 - BiochimicaMG132Caspase 8OsteosarcomaChemistryCaspase 3Cytochromes cFlow CytometryMitochondriaCysteine EndopeptidasesProto-Oncogene Proteins c-bcl-2CaspasesOsteosarcomamedicine.drugmusculoskeletal diseasesProteasome Endopeptidase ComplexCell SurvivalBlotting Westernbcl-X Proteinmacromolecular substancesTransfectionMultienzyme ComplexesCell Line Tumorparasitic diseasesmedicineHumansProtease InhibitorsneoplasmsMolecular BiologySaos-2 cellsDose-Response Relationship DrugCell Biologymedicine.diseaseAcetylcysteineApoptosis osteosarcoma proteasome inhibitorsMicroscopy FluorescenceApoptosisCancer researchProteasome inhibitorTumor Suppressor Protein p53Reactive Oxygen Specieshuman activities
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Coordinated Sumoylation and Ubiquitination Modulate EGF Induced EGR1 Expression and Stability

2011

Background Human early growth response-1 (EGR1) is a member of the zing-finger family of transcription factors induced by a range of molecular and environmental stimuli including epidermal growth factor (EGF). In a recently published paper we demonstrated that integrin/EGFR cross-talk was required for Egr1 expression through activation of the Erk1/2 and PI3K/Akt/Forkhead pathways. EGR1 activity and stability can be influenced by many different post-translational modifications such as acetylation, phosphorylation, ubiquitination and the recently discovered sumoylation. The aim of this work was to assess the influence of sumoylation on EGF induced Egr1 expression and/or stability. Methods We …

Time FactorsTranscription GeneticSUMO proteinlcsh:MedicineUbiquitin-conjugating enzymeBiochemistrychemistry.chemical_compoundEpidermal growth factorMG132protein 1lcsh:ScienceMitogen-Activated Protein Kinase 1Regulation of gene expressionMitogen-Activated Protein Kinase 3MultidisciplinaryProtein translationProtein Stabilitygene expression regulationCell biologyepidermal growth factorResearch Articlemedicine.drugProteasome Endopeptidase Complexendocrine systemkinase 1SUMO-1 ProteinBiologyDNA-binding proteinsGeneticsmedicineHumansBiologySettore BIO/10 - BIOCHIMICAProtein kinase BPI3K/AKT/mTOR pathwayEarly Growth Response Protein 1lcsh:RMitogen-activated proteinProteinsSumoylationRegulatory proteinsenzyme activationRNA stabilityMolecular biologychemistryProteolysisUbiquitin-Conjugating EnzymesProteasome inhibitorlcsh:QEarly growth responseGene expressionCell linePLoS ONE
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Proteasome comprising a beta1 inducible subunit acts as a negative regulator of NADPH oxidase during elicitation of plant defense reactions.

2005

Elicitation of defense reactions in tobacco by cryptogein, triggered a production of active oxygen species (AOS) via the NADPH oxidase, NtrbohD, and an accumulation of beta1din, a defense induced beta-type subunit of 20S proteasome. The proteasome inhibitor, MG132, stimulated this AOS production. Tobacco cells transformed with sense constructs of beta1din showed an inhibition of the AOS production following elicitin treatment, whereas the antisense transformed cells showed a strongly enhanced AOS production. In cells transformed with sense construct of beta1din, the NtrbohD transcripts failed to be induced by cryptogein as observed in control and antisense transformed cells. Conversely, in …

Tobacco BY-2 cellsHypersensitive responseProteasome Endopeptidase ComplexLeupeptinsBiophysics[SDV.BC]Life Sciences [q-bio]/Cellular BiologyBiologyCysteine Proteinase InhibitorsBiochemistrychemistry.chemical_compoundStructural BiologyMG132Sense (molecular biology)TobaccoGeneticsmedicineNADPH OXIDASEPROTEASOMEMolecular Biology[SDV.BC] Life Sciences [q-bio]/Cellular BiologyComputingMilieux_MISCELLANEOUSPlant ProteinsCRYPTOGEINNADPH oxidaseTOBACCO BY-2 CELLSNADPH OxidasesElicitinCell BiologyOligonucleotides AntisenseProtein SubunitsProteasomechemistryBiochemistryProteasome inhibitorbiology.proteinPLANT DEFENSEAOS PRODUCTIONReactive Oxygen SpeciesProteasome Inhibitorsmedicine.drugFEBS letters
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Noetherian type in topological products

2010

The cardinal invariant "Noetherian type" of a topological space $X$ (Nt(X)) was introduced by Peregudov in 1997 to deal with base properties that were studied by the Russian School as early as 1976. We study its behavior in products and box-products of topological spaces. We prove in Section 2: 1) There are spaces $X$ and $Y$ such that $Nt(X \times Y) < \min\{Nt(X), Nt(Y)\}$. 2) In several classes of compact spaces, the Noetherian type is preserved by the operations of forming a square and of passing to a dense subspace. The Noetherian type of the Cantor Cube of weight $\aleph_\omega$ with the countable box topology, $(2^{\aleph_\omega})_\delta$, is shown in Section 3 to be closely related …

Topological manifoldFundamental groupTopological algebraGeneral MathematicsTopological tensor productGeneral Topology (math.GN)Noetherian typeMathematics::General TopologyMathematics - LogicTopological spaceChang’s conjectureTopologyTopological vector spaceTukey mapH-spaceMathematics::LogicFOS: MathematicsPCF theoryTopological ring03E04 54A25 (Primary) 03E55 54B10 54D70 54G10 (Secondary)Box productLogic (math.LO)Mathematics - General TopologyMathematics
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Análisis del comportamiento espacio-temporal intradestino mediante GPS : Una aproximación de los visitantes independientes de crucero en la ciudad de…

2020

El presente trabajo tiene como objetivo profundizar en el análisis de los patrones de comportamiento espacio-temporal de los visitantes en destino, una escala de trabajo insuficientemente desarrollada. La investigación aplica un enfoque multimétodo, que combina el uso de GPS con una encuesta, al conocimiento de los patrones espaciales de los cruceristas que visitan la ciudad de Valencia de manera independiente. Los resultados obtenidos evidencian la polarización de los flujos en el centro histórico de la ciudad, dentro de un patrón mayoritario de único nodo, una dinámica que conviene gestionar adecuadamente para prevenir la congestión y poner en valor otros atractivos urbanos. La redistribu…

Tourism managementGestión turísticaDestinos turísticos inteligentesseguimiento con gpslcsh:G1-922General MedicineGPS trackingSmart tourism destinationsComercialización e Investigación de MercadosSeguimiento con GPSTurismo de cruceros:GEOGRAFÍA [UNESCO]Comportamiento espacio-temporalCruise tourismTime-space behaviourAnálisis Geográfico Regionalgestión turísticacomportamiento espacio-temporaldestinos turísticos inteligentesturismo de cruceroslcsh:Geography (General)UNESCO::GEOGRAFÍA
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Propuesta de un método de evaluación del patrimonio cultural y su aplicación en Cortes de Pallás (Valencia)

2020

Las áreas rurales han experimentado significativas transformaciones socioeconómicas en las últimas décadas, en las cuales ha sido común la competencia de los ámbitos urbanos. Actualmente constituyen espacios multifuncionales caracterizados por el desempeño de nuevas actividades, donde el patrimonio se configura como un recurso esencial en las estrategias de desarrollo territorial (local). No obstante, el diseño de proyectos de valorización requiere la identificación del valor de cada bien. El propósito del estudio es la propuesta de un método de evaluación del patrimonio cultural, conformado por tres sistemas específicos que permiten cuantificar el interés patrimonial de los bienes inmueble…

Touristic resourcesMoorish HuertaGeography Planning and DevelopmentParticipation techniqueslcsh:G1-922Método de evaluación patrimonialDesarrollo localLocal development15. Life on landPatrimonio culturalHuerta moriscaRural heritagePatrimonio ruralTécnicas de participación11. SustainabilityHeritage evaluation methodCortes de PallásCultural heritageGeneral Earth and Planetary SciencesRecursos turísticoslcsh:Geography (General)
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La crisis del modelo tradicional de regadíos del interior valenciano. El caso de Cortes de Pallás: paisajes del agua y patrimonio cultural

2020

Los sistemas tradicionales de regadío forman un legado que se manifiesta mediante lo que conocemos como paisaje y patrimonio del agua. En las áreas del interior valenciano se experimentan disfunciones socioeconómicas que se evidencian paisajísticamente. A partir del análisis en profundidad de un caso de estudio como es la huerta de Cortes de Pallás, en el sector septentrional del macizo del Caroig, se valora si los procesos en ella identificados explican las dinámicas de crisis de los regadíos históricos del interior. El abandono de una parte destacada de las parcelas ha sido una práctica común, aun manteniéndose su morfología y una red de acequias que sigue en funcionamiento. Els sistemes …

Traditional irrigationPaisatges de l'aiguaGeography Planning and DevelopmentPaysages de l'eaupatrimoni hidràulicIrrigation traditionnellelcsh:G1-922Regadíos tradicionalesMón rural en crisiPatrimonio hidráulicoregadius tradicionalsRegadius tradicionalsRural environment crisisPatrimoine hydrauliqueZones rurales en criseEarth-Surface ProcessesMedio rural en crisisWater landscapeHydraulic heritagePaisajes del aguamón rural en crisipaisatges de l’aiguaPatrimoni hidràulicAigua Abastament rurallcsh:Geography (General)Documents d'Anàlisi Geogràfica
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TheSCH9 protein kinase mRNA contains a long 5′ leader with a small open reading frame

1993

The SCH9 yeast gene, that was previously identified as a suppressor of cdc25 and ras1- ras2-ts temperature-sensitive mutants, encodes a putative protein kinase that positively regulates the progression of yeast cells through the G1 phase of the cell cycle. We have determined the structure of the SCH9 transcription unit, using primer extension and S1 mapping techniques. The corresponding mRNA included an unusually long 5' region of more than 600 nucleotides preceding the major open reading frame (ORF). While the latter corresponded to a protein of 824 amino acids, an upstream open reading frame (uORF) within the 5' leader could potentially encode a 54 amino acid peptide. To investigate the r…

Transcription GeneticFive prime untranslated regionMolecular Sequence DataSaccharomyces cerevisiaeBioengineeringSaccharomyces cerevisiaeBiologyApplied Microbiology and BiotechnologyBiochemistryOpen Reading FramesGene Expression Regulation FungalUpstream open reading frameGeneticsAmino Acid SequenceRNA MessengerGenes SuppressorAllelesGeneticsMessenger RNABase SequenceG1 PhaseNucleic acid sequenceRNA Fungalbiology.organism_classificationFusion proteinOpen reading frameRegulatory sequenceMutationProtein KinasesBiotechnologyYeast
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Ecoviles a Espanya: buscant una transformació social emancipadora?

2020

Segons dades de la Global Ecovillage Network (2018), l'Estat espanyol és actualment el segon país més important del món, després dels Estats Units, en nombre d'ecoviles, la xifra de les quals no ha cessat de créixer al llarg dels darrers anys. Seguint la teoria d'Erik Olin Wright sobre transformacions socials emancipadores, tractarem la qüestió de si aquest boom representa una mostra d'una transformació social incipient i d'un canvi cultural que està experimentant el medi rural. Aquest treball es divideix en cinc seccions principals. La primera introdueix el problema, per abordar tot plegat la metodologia realitzada per a l'estudi de 29 ecoviles a Espanya utilitzant sis variables sobre inte…

Transformation socialeEspagneTransformación socialtransformació socialEspañaGeography Planning and Developmentlcsh:G1-922espais ruralsEspais ruralsRural areasÉcovillagesSocial transformationEcoaldeasespanyaSpainEspaces rurauxecovilesEspacios ruralesEcovilesEspanyaTransformació socialEcovillageslcsh:Geography (General)Earth-Surface ProcessesDocuments d'Anàlisi Geogràfica
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