Search results for "GAIN"

showing 10 items of 625 documents

The importance of relation-specific investments in capital structure decision: the case of the biopharmaceutical industry

2012

According to capital structure literature, bilateral relationships with external partners have a strong impact on a firm’s financing decisions because they involve relation-specific investments that would lose most of their value in case of liquidation. By adjusting their capital structure firms can reduce liquidation risks and incentive their partners to undertake such investments. In this paper we extend these arguments to strategic alliances in the context of biotechnology industry, where bilateral relationships are formed to advance the commercialization of innovation and R-S investments are a primary issue. We investigate alliances heterogeneity and analyze whether partnerships possess…

Capital structure R-S investments bargaining power biotechnology industrySettore ING-IND/35 - Ingegneria Economico-Gestionale
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Interactions between Polyamines and Abiotic Stress Pathway Responses Unraveled by Transcriptome Analysis of Polyamine Overproducers

2011

Plant development and productivity are negatively regulated by adverse environmental conditions. The identification of stress-regulatory genes, networks, and signaling molecules should allow the development of novel strategies to obtain tolerant plants. Polyamines (PAs) are polycationic compounds with a recognized role in plant growth and development, as well as in abiotic and biotic stress responses. During the last years, knowledge on PA functions has been achieved using genetically modified plants with altered PA levels. In this review, we combine the information obtained from global transcriptome analyses in transgenic Arabidopsis plants with altered putrescine or spermine levels. Compa…

Cell signalingArabidopsisBiologyModels BiologicalBiochemistryTranscriptomechemistry.chemical_compoundStress PhysiologicalArabidopsisPolyaminesGeneticsPlant defense against herbivoryCalcium SignalingMolecular BiologyAbscisic acidPlant Stress—Special Issue 1Review ArticlesAbiotic stressfungifood and beveragesBiotic stressPlants Genetically Modifiedbiology.organism_classificationchemistryBiochemistryPutrescineMolecular MedicineTranscriptomeGenome PlantAbscisic AcidSignal TransductionBiotechnologyOMICS: A Journal of Integrative Biology
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Comparison between tumors in plants and human beings: Mechanisms of tumor development and therapy with secondary plant metabolites

2019

Abstract Background Human tumors are still a major threat to human health and plant tumors negatively affect agricultural yields. Both areas of research are developing largely independent of each other. Treatment of both plant and human tumors remains unsatisfactory and novel therapy options are urgently needed. Hypothesis The concept of this paper is to compare cellular and molecular mechanisms of tumor development in plants and human beings and to explore possibilities to develop novel treatment strategies based on bioactive secondary plant metabolites. The interdisciplinary discourse may unravel commonalities and differences in the biology of plant and human tumors as basis for rational …

Cellular immunityPhytochemicalsPlant TumorsPhysical CarcinogenesisSecondary MetabolismPharmaceutical ScienceBiologymedicine.disease_cause03 medical and health sciences0302 clinical medicineImmune systemCancer stem cellNeoplasmsDrug DiscoveryBiological CarcinogenesisPlant defense against herbivorymedicineAnimalsHumansPlant ImmunityPlant Physiological PhenomenaPlant Diseases030304 developmental biologyPharmacology0303 health sciencesAntibiotics Antineoplasticfungifood and beveragesPlantsAntineoplastic Agents PhytogenicComplementary and alternative medicineAgrobacterium tumefaciensDrug Resistance Neoplasm030220 oncology & carcinogenesisCancer researchMolecular MedicineCarcinogenesisPhytomedicine
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Acute Respiratory Distress Syndrome Associated with Tumor Lysis Syndrome in a Child with Acute Lymphoblastic Leukemia

2015

Tumor lysis syndrome is a serious and dangerous complication usually associated with antiblastic treatment in some malignancies characterized by high cell turn-over. Mild or severe electrolyte abnormalities including high serum levels of uric acid, potassium, phosphorus, creatinine, bun and reduction of calcium can be responsible for multi-organ failure, involving mostly kidneys, heart and central nervous system. Renal damage can be followed by acute renal failure, weight gain, progressive liver impairment, overproduction of cytokines, and subsequent maintenance of multi-organ damage. Life-threatening acute respiratory failure associated with tumor lysis syndrome is rare. We describe a chil…

Central nervous systemlcsh:MedicineCase ReportAcute respiratory distressacute lymphoblastic leukemiaPediatricschemistry.chemical_compoundmedicineacute respiratory distress syndrome tumor lysis syndrome acute lymphoblastic leukemia childhoodDiffuse alveolar damagechildhoodCreatininebusiness.industrylcsh:Rlcsh:RJ1-570lcsh:Pediatricsacute respiratory distress syndromemedicine.diseaseTumor lysis syndromemedicine.anatomical_structurechemistryImmunologyUric acidmedicine.symptomtumor lysis syndromeComplicationbusinessWeight gainPediatric Reports
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<strong>Review of some little-known benthic hydroids (Cnidaria, Hydrozoa) from the Southern Ocean</strong>

2015

A number of benthic hydroid species inhabiting the Southern Ocean are insufficiently characterized. A revision of eight little-known Antarctic species of the order Anthoathecata was made, based on the study of type material. Some of the species have not been recorded since their original description a century ago. Four species (Bimeria corynopsis, Bougainvillia macloviana, ?Koellikerina belgicae and Rhizorhagium antarcticum) belong to the family Bougainvilliidae, two species (Hydractinia angusta and H. dendritica) to the family Hydractiniidae, Perarella clavata to the family Cytaeididae and, finally, Rhysia halecii to the family Rhysiidae. For each species a list of synonyms, a description,…

CnidariabiologyBenthic zoneHydractiniaEcologyHydroid (zoology)Animal Science and ZoologyBougainvilliaTaxonomy (biology)biology.organism_classificationCoelenterataEcology Evolution Behavior and SystematicsHydrozoaZootaxa
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Política económica y redistribución: hacia una nueva arquitectura “pre-distributiva” de la política de rentas

2020

El presente trabajo diseña una política de rentas que podríamos llamar “pre-distributiva”. Su principal objetivo es describir la arquitectura de una política de rentas amplia, que tendría, básicamente, tres pilares: a) el reforzamiento de la capacidad redistributiva de la negociación colectiva, b) el establecimiento de una “norma salarial redistributiva” coordinada a nivel europeo y c) el aumento del Salario Mínimo Interprofesional. Dicha política de rentas podría contribuir a una distribución más equitativa de las rentas primarias del trabajo. 

Collective bargainingEuropean levelbusiness.industrymedia_common.quotation_subjectWelfare economicsWageLabor incomeEconomicsDistribution (economics)Minimum wagebusinessmedia_commonInternational Review of Economic Policy-Revista Internacional de Política Económica
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An interactive approach to multiple criteria optimization with multiple decision-makers

1986

In this article we propose a formal man-machine interactive approach to multiple criteria optimization with multiple decision makers. The approach is based on some of our earlier research findings in multiple criteria decision making. A discrete decision space is assumed. The same framework may readily be used for multiple criteria mathematical programming problems. To test the approach two experiments were conducted using undergraduate Business School students as subjects in Finland and in the United States. The context was, respectively, a high-level Finnish labor-management problem and the management-union collective bargaining game developed at the Krannert Graduate School of Management…

Collective bargainingOperations researchManagement scienceComputer scienceDecision theoryGeneral EngineeringMultiple criteriaContext (language use)Social decisionSpace (commercial competition)Research findingsTest (assessment)Naval Research Logistics Quarterly
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BARGAINING WITH COMMITMENT UNDER AN UNCERTAIN DEADLINE

2006

We consider an infinite horizon bargaining game in which a deadline can arise with positive probability and where players possess an endogenous commitment device. We show that for any truncation of the game, the equilibrium agreement can only take place if the deadline arises within this finite horizon. Since the deadline is an uncertain event, the equilibrium exhibits agreements which are delayed with positive probability.

Commitment deviceComputer Science::Computer Science and Game TheoryGeneral Computer ScienceTruncationFinite horizonC78 [Bargaining endogenous commitment delays uncertain deadline JEL Classification]jel:M2MicroeconomicsEconomicsjel:C0Infinite horizonStatistics Probability and UncertaintyBusiness and International Managementjel:D5jel:B4Mathematical economicsComputer Science::Operating Systemsjel:C6jel:D7Positive probabilityComputer Science::Databasesjel:C7Event (probability theory)International Game Theory Review
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Constrained consensus for bargaining in dynamic coalitional TU games

2011

We consider a sequence of transferable utility (TU) games where, at each time, the characteristic function is a random vector with realizations restricted to some set of values. We assume that the players in the game interact only with their neighbors, where the neighbors may vary over time. The main contributions of the paper are the definition of a robust (coalitional) TU game and the development of a distributed bargaining protocol. We prove the convergence with probability 1 of the bargaining protocol to a random allocation that lies in the core of the robust game under some mild conditions on the players' communication graphs.

Computer Science::Computer Science and Game TheoryMathematical optimizationBargaining problemSequential gameRobustness (computer science)Computer scienceComputingMilieux_PERSONALCOMPUTINGCombinatorial game theoryGraph theoryTransferable utilityMathematical economicsGame theoryIEEE Conference on Decision and Control and European Control Conference
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Super-orthogonal space-time trellis codes with differential phase modulation for noncoherent mobile communication systems

2010

In this paper, we show how to design super-orthogonal space-time trellis codes (SOSTTCs) using the differential binary phase-shift keying (PSK) modulation for noncoherent communication systems, for which the knowledge of the channel state information (CSI) at the receiver is not necessary. Moreover, a new decoding algorithm with reduced decoding complexity is proposed. In all simulations, a geometric two-ring channel model is employed to evaluate the performance of the SOSTTCs. The simulation results show that the proposed decoding algorithm has the same decoding performance compared with the traditional decoding strategy, while the new algorithm reduces significantly the overall computing …

Computer sciencebusiness.industryList decodingKeyingData_CODINGANDINFORMATIONTHEORYTrellis (graph)Sequential decodingCoding gainChannel state informationBit error rateTelecommunicationsbusinessAlgorithmDecoding methodsComputer Science::Information TheoryPhase-shift keyingInternational Conference on Communications and Electronics 2010
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