Search results for "GELS"

showing 10 items of 671 documents

The influence of improvisation activities on speaking confidence of EFL student teachers

2020

The purpose of the present study was to explore the application of improvisation activities in English teacher education, specifically to investigate their influence on the student teachers’ confidence when speaking English spontaneously. The improvisation activities consisted of storytelling, conversations and status expressions. Data were drawn from both pre- and post-questionnaires and retrospective texts. The statistical findings showed significant improvements in the student teachers’ level of speaking confidence and degree of relaxation while speaking English. The findings of the qualitative analysis confirmed this, and participants stated that the fun, collaboration and high degree o…

Improvisation:Humaniora: 000::Språkvitenskapelige fag: 010::Engelsk språk: 020 [VDP]improvisation activitieseducationStudent teacherspeaking confidenceVDP::Samfunnsvitenskap: 200::Pedagogiske fag: 280lcsh:Education (General)EducationPeer reviewreluctant speaker:Samfunnsvitenskap: 200::Pedagogiske fag: 280 [VDP]Mathematics educationoral communicationPsychologylcsh:L7-991VDP::Social science: 200::Education: 280efl/eltVDP::Humaniora: 000::Språkvitenskapelige fag: 010teacher education
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Physico-chemical and mechanical characterization of in-situ forming xyloglucan gels incorporating a growth factor to promote cartilage reconstruction

2016

Abstract The development of growth factors is very promising in the field of tissue regeneration but specifically designed formulations have to be developed in order to enable such new biological entities (NBEs). In particular, the range of therapeutic concentrations is usually very low compared to other active proteins and the confinement in the target site can be of crucial importance. In-situ forming scaffolds are very promising solutions for minimally invasive intervention in cartilage reconstruction and targeting of NBEs. In this work injectable, in-situ forming gels of a temperature responsive partially degalactosylated xyloglucan (Deg-XG) incorporating the growth factor FGF-18 are fo…

In situInjectionFibroblast Growth FactorChemical Phenomenamedicine.medical_treatment02 engineering and technologyFibroblast growth factor01 natural sciencesViscositychemistry.chemical_compoundTissue ScaffoldSettore BIO/10 - BiochimicaComposite materialGlucansGelTissue ScaffoldsIn-situ forming gelsViscosityGrowth factor021001 nanoscience & nanotechnologyGlucanXyloglucanmedicine.anatomical_structureSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiMechanics of MaterialsXylansMaterials Science (all)0210 nano-technologyMaterials scienceMechanical PhenomenaInjectable scaffoldsBioengineeringCondensed Matter Physic010402 general chemistryInjectable scaffoldInjectionsBiomaterialsShear modulusXylanChondrocytesmedicineAnimalsMechanics of MaterialXyloglucanCartilage reconstructionCell ProliferationMechanical PhenomenaAnimalCartilageGrowth factorMechanical EngineeringIn-situ forming gelChondrocyte0104 chemical sciencesFibroblast Growth FactorsMolecular WeightCartilagechemistryBiophysicsCattleSettore CHIM/07 - Fondamenti Chimici Delle TecnologieTemperature-responsiveGels
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In situ formation of steroidal supramolecular gels designed for drug release

2013

In this work, a steroidal gelator containing an imine bond was synthesized, and its gelation behavior as well as a sensitivity of its gels towards acids was investigated. It was shown that the gels were acid-responsive, and that the gelator molecules could be prepared either by a conventional synthesis or directly in situ during the gel forming process. The gels prepared by both methods were studied and it was found that they had very similar macroand microscopic properties. Furthermore, the possibility to use the gels as carriers for aromatic drugs such as 5-chloro-8-hydroxyquinoline, pyrazinecarboxamide, and antipyrine was investigated and the prepared two-component gels were studied with…

In situMagnetic Resonance SpectroscopykolesteroliImineSupramolecular chemistryPharmaceutical ScienceArticleChloroquinolinolsAnalytical ChemistryDelayed-Action Preparationslcsh:QD241-441chemistry.chemical_compoundgeeliDrug Delivery Systemslcsh:Organic chemistryDrug DiscoveryPolymer chemistryMoleculeddc:530Physical and Theoretical Chemistryta116drug releaseOrganic ChemistryorganogelcholesterolNuclear magnetic resonance spectroscopyacid-responsiveHydrogen-Ion ConcentrationchemistryChemistry (miscellaneous)in situ gelationDelayed-Action PreparationsDrug deliveryDrug releaseMolecular Medicineorganogel; acid-responsive; cholesterol; <i>in situ</i> gelation; drug releaseGels
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In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats

2019

Graphical abstract

In situPO Propylene oxideIV IntravenousP338 Poloxamer 338lcsh:RS1-441Pharmaceutical Sciencechemistry.chemical_compoundn Sample sizeSD Standard deviationIM Intramuscularchemistry.chemical_classificationC0 Analyte plasma concentration at time zeroDoE Design of experimentsUV UltravioletPharmacology. TherapyK2.EDTA Potassium ethylenediaminetetraacetic acidLC–MS/MS Liquid chromatography-tandem mass spectrometryH&E Hematoxylin and eosintmax Sampling time to reach the maximum observed analyte plasma concentrationIn situ forming gelsCMC Critical micellar concentrationCmax Maximum observed analyte plasma concentrationIntramuscular injectionDN Dose normalizedGPT Gel point temperaturePLGA Poly-(DL-lactic-co-glycolic acid)TFA Trifluoroacetic acidCAN AcetonitrileATP Adenosine 5′ triphosphateSalt (chemistry)Polyethylene glycolPoloxamerArticlelcsh:Pharmacy and materia medicaPharmacokineticsIn vivoUHPLC Ultra-high performance liquid chromatographyPharmacokineticsAUClast Area under the analyte concentration versus time curve from time zero to the time of the last measurable (non-below quantification level) concentrationEO Ethylene oxideNMP N-methyl-2-pyrrolidoneComputingMethodologies_COMPUTERGRAPHICSAUC∞ Area under the analyte concentration vs time curve from time zero to infinite timeP407 Poloxamer 407In vitro releasePoloxamerCMT Critical micellar temperatureGel erosionIn vitrot1/2 Apparent terminal elimination half-lifechemistryMDR-TB Multi-drug resistant tuberculosisAUC80h Area under the analyte concentration versus time curve from time zero to 80 htlast Sampling time until the last measurable (non-below quantification level) analyte plasma concentrationMRM Multiple reaction monitoringNuclear chemistrySustained releaseInternational Journal of Pharmaceutics: X
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Timing effect of intramyocardial hydrogel injection for positively impacting left ventricular remodeling after myocardial infarction

2015

Intramyocardial injection of various injectable hydrogel materials has shown benefit in positively impacting the course of left ventricular (LV) remodeling after myocardial infarction (MI). However, since LV remodeling is a complex, time dependent process, the most efficacious time of hydrogel injection is not clear. In this study, we injected a relatively stiff, thermoresponsive and bioabsorbable hydrogel in rat hearts at 3 different time points - immediately after MI (IM), 3 d post-MI (3D), and 2 w post-MI (2W), corresponding to the beginnings of the necrotic, fibrotic and chronic remodeling phases. The employed left anterior descending coronary artery ligation model showed expected infar…

InjectionTime FactorsMacrophageMyocardial InfarctionInfarction02 engineering and technology030204 cardiovascular system & hematologyCardiac tissue engineeringAntigens CD31Hydrogel Polyethylene Glycol DimethacrylateHeart Ventricle0302 clinical medicineFibrosisMyocardial infarctionInflammation MediatorVentricular RemodelingIntervention timing021001 nanoscience & nanotechnologyPlatelet Endothelial Cell Adhesion Molecule-1Neutrophil InfiltrationMechanics of MaterialsSelf-healing hydrogelsCardiologyCytokinesFemalemedicine.symptomInflammation Mediators0210 nano-technologymedicine.medical_specialtyMaterials scienceTime FactorHeart VentriclesBiophysicsInflammationBioengineeringCeramics and CompositeAnterior Descending Coronary ArteryArticleInjectionsBiomaterials03 medical and health sciencesInternal medicinemedicineAnimalsMechanics of MaterialVentricular remodelingCytokineActinAnimalMacrophagesMyocardiummedicine.diseaseBiomaterialInjectable materialActinsHydrogelRats Inbred LewCeramics and CompositesLigation
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Tunable and Large-Scale Model Network StarPEG-DNA Hydrogels

2021

The use of DNA as a building block in synthetic polymer hydrogels promises high levels of programmability regarding sol/gel temperatures, tunable bond lifetimes, biocompatibility, and interaction w...

Inorganic Chemistrychemistry.chemical_compoundMaterials sciencePolymers and PlasticsBiocompatibilitychemistryBlock (telecommunications)Organic ChemistrySelf-healing hydrogelsMaterials ChemistryNanotechnologySynthetic polymerDNAMacromolecules
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Self strengthening, Load Bearing Ionic Liquid Gels for Environmental Remediation

Ionic Liquid gels self strenghthening gels dyes adsorptionSettore CHIM/06 - Chimica Organica
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Di- and Tricationic Organic Salts: an Overview of Their Properties and Applications

2014

During recent years growing interest has been devoted to the synthesis and applications of polycationic organic salts. Among them, di- and tricationic organic salts can be considered the natural evolution of monocationic ones. These last have given rise to the large class of ionic liquids. In the cases of di- and tricationic organic salts, the potential to change their structural features simply by varying the properties either of the charged heads or of the spacers separating them provides the opportunity to obtain materials suitable for different applications. This review article highlights recent progress in the study of the properties of di- and tricationic organic salts, as well as in …

Ionic Liquid Liquid crystals Organic Salts Gels AnionsSettore CHIM/06 - Chimica Organica
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Anion and ionic liquid effects on ionogel phases formation

Geminal organic salts have been recently introduced as the third generation of ionic liquids.1 Like their monocationic precursors they generally show high thermal stability and low corrosiveness, as well as high polarity and structural order degree.2 All these features make them good candidates to be used in the formation of conductive gel phases, that afterwards may find application as organized reaction media or in the preparation of dye sensitized solar cells.3 In this context, we have recently synthesized some task specific geminal organic salts and investigated their behaviour as gelators. The obtained salts were able to gel ionic liquid solutions. In order to have information about th…

Ionic Liquids Ionogels Task specific organic saltsSettore CHIM/06 - Chimica Organica
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The importance of supramolecular reaction media in catalysis

Ionic liquids supramolecular gels ionogels chiral catalysts
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