Search results for "GERB"

1994

Giraffid remains from several Neogene localities from the Temel Basin (Spain) are stu­ died. The material belongs to the following sites: Masia de la Roma and Masia del Barbo (Vallesian); Masada del Valle 2 (Turolian); La Gloria 4 and La Calera (Alfambrian). Fos­ sils recently obtained are described, with special emphasis on the Pliocene taxa that were previously unrecorded in this basin. The presence of Decennatheriumpachecoi in the Va­ llesian and Birgerbohlinia schaubi in the Turolian is specified here. In order to make a dis­ tinction between both species two characteristics can be pointed out among the rest: the postcranial skeleton of Decennatherium is more slender than the one of Bir…

Open and closed inflorescences: more than simple opposites

2010

The absence of a terminal flower in inflorescences (‘open inflorescences’) is currently explained by the maintenance of putative stem-cells in the central zone (CZ) of the inflorescence meristem (IM) governed by the CLAVATA– WUSCHEL regulatory loop. Disruption of this regulatory pathway, as in Arabidopsis TERMINAL FLOWER LOCUS 1 mutants, leads to terminal flower production. However, recent studies in other taxa reveal novel mechanisms of inflorescence termination; for example, the SEPALLATA-like MADS-box floral identity gene GERBERA REGULATOR OF CAPITULUM DEVELOPMENT 2 in Gerbera excludes the retention of a CZ as an ontogenetic cause for the openness of these inflorescences. Moreover, compa…

THE REHABILITATION THROUGH EXTERNAL PRESTRESSING OF HISTORICAL REINFORCED CONCRETE BRIDGES WITH REDUCED PERFORMANCE: A CASE STUDY

2022

Many existing reinforced concrete bridges exhibit behaviour at the Service Limit State and the Ultimate Limit State which can be considered unsatisfactory with respect to the current provisions of Codes, but which are actually deficiencies deriving from obsolete calculation methods, structure age, material degradation, diffuse or localized corrosion and increased loads. Among these, cantilever bridges with half-joints may present a decrease in global safety coefficients for the most stressed current sections of the deck or in the local ones, that affect the performance of elements sensitive to degradation, such as Gerber saddles. In these cases, simple strengthening interventions through ex…

The desert gerbil Psammomys obesus as a model for metformin-sensitive nutritional type 2 diabetes to protect hepatocellular metabolic damage: Impact …

2017

Introduction While metformin (MET) is the most widely prescribed antidiabetic drug worldwide, its beneficial effects in Psammomys obesus (P. obesus), a rodent model that mimics most of the metabolic features of human diabetes, have not been explored thoroughly. Here, we sought to investigate whether MET might improve insulin sensitivity, glucose homeostasis, lipid profile as well as cellular redox and energy balance in P. obesus maintained on a high energy diet (HED). Materials and methods P. obesus gerbils were randomly assigned to receive either a natural diet (ND) consisting of halophytic plants (control group) or a HED (diabetic group) for a period of 24 weeks. MET (50 mg/kg per os) was…

Significant correlations between certain spectra of atmospherics and daily periodic activities of Mongolian gerbils (Meriones unguiculatus L.).

1995

We describe significant correlations between 10 and 28 kHz atmospherics (according to Baumer) and the running activities of ten Mongolian gerbils (Meriones unguiculatus L.) depending on their circadian rhythm over a 42-day period (August/September 1988).

Dynamic in vivo Imaging of Microvasculature and Perfusion by Miniaturized Confocal Laser Microscopy

2008

<i>Introduction:</i> Microvasculature and associated pathologies mandate dynamic imaging. We evaluated a novel miniaturized confocal laser scanning probe for in vivo visualization of blood vessels, blood flow, cell tracking and perfusion in both healthy rodents and disease models.<i> Methods:</i> The hand-held confocal microscopy system allowed a 500- to 2,400-fold magnification at a dynamically variable imaging depth. Different intravital stains were used alone or in combination for tissue, nuclear, plasma and vascular endothelial cell staining and for blood flow visualization, and targeted staining for individual cell populations. <i>Results:</i> Precis…

Microcirculatory alterations in a mongolian gerbil sinus-vein thrombosis model

2001

Summary Background and purpose. The pathophysiology of sinus-vein thrombosis (SVT) is still controversial in patients and experimental animals, the microcirculatory alterations in particular. This study was designed to develop a new sinus-vein thrombosis model and to further elucidate pathophysiological events such as the relationship between local and regional cerebral blood flow and haemoglobin oxygen saturation (HbSO2), changes of the microvasculature, leukocyte behaviour and brain tissue damage. Methods. In a first experimental series, animals were divided into two groups which resulted from different procedures of inducing SVT. In the SSS middle occlusion group (SMO group), SVT was ind…

Characterization of rodent pineal astrocytes by immunofluorescence microscopy using a monoclonal antibody (J1-31).

1987

In previous studies pineal astrocytes have been characterized immunohistochemically mainly by use of antisera to glial fibrillary acidic protein. Because of the recent demonstration of this protein in non-astrocytic cells the question of its specificity as an astrocytic marker has been raised. A possible alternative tool for characterizing pineal astrocytes is the J1-31 monoclonal antibody, which is directed against a 30 000 dalton astrocytic protein clearly distinguishable from glial fibrillary acidic protein. Immunofluorescence microscopy of this antibody in the pineal gland of rat and guinea-pig revealed a staining pattern similar to that obtained by glial acidic fibrillary protein antis…

Stimulation of Serotonin-N-Acetyltransferase Activity in the Pineal Gland of the Mongolian Gerbil (Meriones unguiculatus) by Intracerebroventricular …

1989

There is ever-increasing evidence that intrapineal peptides have an important role in the modulation of pineal melatonin synthesis. In the pineal gland of the Mongolian gerbil (Meriones unguiculatus), we have previously shown the presence of VIP-immunoreactive nerve fibers as well as pinealocytic VIP receptors. To assess the functional significance of these findings, 10 microliters of a 1 microM or 1 nM solution of VIP were injected into the lateral ventricle of gerbils over a period of 10 min. Animals were killed 1.5 hr after injection, and the superficial pineal glands were excised and assayed for N-acetyltransferase (NAT) activity. Injection of the 1 microM VIP solution stimulated the NA…

Comparative investigations on the actions of ACTH1-24, somatostatin, neurotensin, substance P and vasopressin on locus coeruleus neuronal activity in…

1987

A considerable number of neuropeptides have been localized immunohistochemically in the area of the locus coeruleus of the rat. The objective of this study was to assess the actions of some of these transmitter candidates on spontaneously active locus coeruleus neurons in vitro. The effects of bath-applied peptides on the discharge rate of individual locus coeruleus neurons were investigated. A midpontine slice preparation of the gerbil brain was used. Excitatory dose-dependent effects were found with four peptides with the following rank order of potency: Substance P, (Arg8)-vasopressin, neurotensin, ACTH1–24. Somatostatin hyperpolarized all neurons tested. Given the pronounced effects see…