Search results for "GLUTAMATE"
showing 10 items of 434 documents
The pallial amygdala of amniote vertebrates: evolution of the concept, evolution of the structure
2002
Embryological studies indicate that the amygdala includes pallial structures, namely the cortical amygdala (olfactory and vomeronasal) and the basolateral complex deep to it. In squamate reptiles, the cortical amygdala includes secondary olfactory (the ventral anterior amygdala) and vomeronasal centres (the nucleus sphericus). In birds, the situation is far less clear, due to the relative underdevelopment of the chemosensory systems. The basolateral amygdala of squamate reptiles includes two ventropallial structures: the posterior dorsal ventricular ridge and the lateral amygdala. Like their mammalian counterparts, these centres give rise to glutamatergic projections to the striatal (centro…
NovelAmycolatopsis balhimycinabiochemical abilities unveiled by proteomics
2014
Amycolatopsis balhimycina DSM5908 is an actinomycete producer of balhimycin, an analogue of vancomycin, the antibiotic of ‘last resort’ against multidrug-resistant Gram-positive pathogens. Most knowledge on glycopeptide biosynthetic pathways comes from studies on A. balhimycina as this strain, among glycopeptide producers, is genetically more amenable. The recent availability of its genome sequence allowed to perform differential proteomic analyses elucidating key metabolic pathways leading to antibiotic production in different growth conditions. To implement proteomic data on A. balhimycina derived from 2-DE approaches and to identify novel components, a combined approach based on protein …
Accelerated bang recovery in Drosophila genderblind mutants
2008
International audience; Cystine-glutamate transporters import cystine into cells for glutathione synthesis and protection from oxidative stress, but also export significant amounts of glutamate. Increasing evidence suggests that 'ambient extracellular glutamate' secreted by cystine-glutamate transporters in the nervous system modulates glutamatergic synapse strength and behavior. To date, the only cystine-glutamate transporter mutants examined behaviorally are Drosophila genderblind mutants. These animals contain loss-of-function mutations in the 'genderblind' gene, which encodes an xCT subunit essential for cystine-glutamate transporter function. Genderblind was named based on a mutant cou…
Nonsynonymous SNPs in human tas1r1, tas1r3, mGluR1 and individual taste sensitivity to glutamate
2009
; Nonsynonymous SNPs in human tas1r1, tas1r3, mGluR1 and individual taste sensitivity to glutamate. 31. annual meeting - Association for chemoreception sciences (AChemS)
The multiple facets of Cajal-Retzius neurons.
2021
ABSTRACTCajal-Retzius neurons (CRs) are among the first-born neurons in the developing cortex of reptiles, birds and mammals, including humans. The peculiarity of CRs lies in the fact they are initially embedded into the immature neuronal network before being almost completely eliminated by cell death at the end of cortical development. CRs are best known for controlling the migration of glutamatergic neurons and the formation of cortical layers through the secretion of the glycoprotein reelin. However, they have been shown to play numerous additional key roles at many steps of cortical development, spanning from patterning and sizing functional areas to synaptogenesis. The use of genetic l…
Non synonymous nucleotide polymorphisms in human taste receptors and individual taste sensitivity to glutamate
2008
National audience
Relation phénotype-génotype dans le cas de la sensibilité gustative au glutamate
2009
National audience
Taste receptors to L-glutamate
2007
National audience
Meshing individual differences in taste sensitivity with genotype: cSNPs in candidate taste receptors for glutamate are necessary but not sufficient …
2007
International audience