Search results for "GRI"

showing 10 items of 10209 documents

Experimental analysis of the potential validity of Lorenzini’s hypothesis to treat COVID-19 patients

2021

The present research was aimed at testing the potential validity of Lorenzini’s hypothesis against Covid-19, based on the use of far UV-C rays directly on the patient’s ill lungs, so to significantly reduce the virus presence and with it the interstitial pneumonia, the cause of most deaths. Not having had the chance to experiment directly on the SARS-CoV-2, we shifted to a plant virus called TSWV, which has some common characteristics with SARS-CoV-2, so making our tests significant. The virus was suitably utilized so to affect an opportune range of pepper plants, after a treatment with 2 UV-C lamps, of which just one spreading far UV-C rays. Results showed that the effect of a quick exposi…

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)business.industrySARS-CoV-2Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)fungiGeneral EngineeringVirologyVirusAmpullae of LorenziniMedicineExperimental activityGeneral Agricultural and Biological SciencesbusinessCovid-19UV-C rayTSWVGeneral Environmental Science
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High Biological Value Compounds Extraction from Citrus Waste with Non-Conventional Methods.

2020

Citrus fruits are extensively grown and much consumed around the world. Eighteen percent of total citrus cultivars are destined for industrial processes, and as a consequence, large amounts of waste are generated. Citrus waste is a potential source of high biological value compounds, which can be used in the food, pharmaceutical, and cosmetic industries but whose final disposal may pose a problem due to economic and environmental factors. At the same time, the emerging need to reduce the environmental impact of citrus waste and its responsible management has increased. For these reasons, the study of the use of non-conventional methods to extract high biological value compounds such as caro…

2019-20 coronavirus outbreakHealth (social science)Plant ScienceReviewUltrasound assistedlcsh:Chemical technology01 natural sciencesHealth Professions (miscellaneous)MicrobiologyMicrowave assisted0404 agricultural biotechnologynon-conventional methodsPotential sourcelcsh:TP1-1185010401 analytical chemistryExtraction (chemistry)Supercritical fluid extractionfood and beveragesWater extractionBiological value04 agricultural and veterinary sciencesPulp and paper industry040401 food science0104 chemical scienceshigh-biological-value compoundsextractionEnvironmental sciencecitrus wasteFood ScienceFoods (Basel, Switzerland)
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Horses Could Perceive Riding Differently Depending on the Way They Express Poor Welfare in the Stable

2020

International audience; This study investigated the relationships between four behavioral and postural indicators of a compromised welfare state in loose boxes (stereotypies, aggressive behaviors toward humans, withdrawn posture reflecting unresponsiveness to the environment, and alert posture indicating hypervigilance) and the way horses perceived riding. This perception was inferred using a survey completed by the usual riding instructor and during a standardized riding session (assessment of behaviors and postures, qualitative behavior assessment (QBA) and characterization of the horses' locomotion using an inertial measurement unit). In accordance with ear and tail positions and the QBA…

2019-20 coronavirus outbreakKinematicsCoronavirus disease 2019 (COVID-19)040301 veterinary sciencesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)media_common.quotation_subjectEmotionsPosture[SDV.SA.ZOO]Life Sciences [q-bio]/Agricultural sciences/ZootechnyHorse0403 veterinary scienceAnimal welfareAnimal welfarePerceptionmedicineAnimalsHorsesNegative perceptionmedia_commonBehaviorEquine0402 animal and dairy science04 agricultural and veterinary sciencesHypervigilance040201 dairy & animal scienceSpineHousing conditionsStereotyped Behaviormedicine.symptomPsychologyhuman activitiesWelfareClinical psychologyJournal of Equine Veterinary Science
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2-3 gadīgu bērnu runas sekmēšana vingrinājumos un rotaļās

2017

Kvalifikācijas darba nosaukums: „2–3 gadīgu bērnu runas sekmēšana vingrinājumos un rotaļās” Darba autore:.Valērija Kudrjašova Darba zinātniskais vadītājs: Mg. paed. Irēna Miltiņa Pētījuma mērķis: Teorētiski un praktiski izzināt runas attīstīšanas iespējas vingrinājumos un rotaļās agrajā bērnībā. Pētījuma teorētiskā daļa balstās uz I. Elnebijas, G. Svences, D. Lieģenieces, J. Udaļcovas, V. Romenkovas, D. Dzinteres, A. Ļublinskas, A. Šponas, J. Tihejevas, M. Maksakova, Ļ. Vigodska, V. Gerbovas, Miltiņas I., u.c. teorētiķu atziņām. Teorētiskajā daļā analizētas agrās bērnības fiziskās, sociālās un psihiskās attīstības īpatnības, pieaugušo un bērnu sadarbība runas attīstības sekmēšanai. Tiek kon…

2–3 gadīgie bērniPirmsskolas pedagoģijarunas prasmju attīstībavingrinājumirotaļasRuna un valoda
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Vingrinājumu un rotaļu izmantošana fonētisko traucējumu novēršanai 3-4 gadus veciem bērniem

2021

Diplomdarba autors: Kristīne Lielmane Diplomdarba temats: “Vingrinājumu un rotaļu izmantošana fonētisko traucējumu novēršanai 3 – 4 gadus veciem bērniem” Mērķis: teorētiski pētīt un praktiski izzināt vingrinājumu un rotaļu izmantošanas iespējas 3 – 4 gadīgu bērnu fonētisko traucējumu novēršanai. Darba pirmajā nodaļā tiek iepazīstināts ar 3 – 4 gadus vecu bērnu vispārējo attīstību, skaņu izrunas traucējumiem, to izpausmēm. Tiek apskatīts kāda nozīme ir vingrinājumiem un rotaļām fonētisko traucējumu novēršanā. Otrajā nodaļā tika veikts empīriskais pētījums, kā ar vingrinājumu un rotaļu palīdzību var veicināt vidējā vecuma bērnu fonētisko traucējumu novēršanu. Autore veic novērojumu un atlasa …

3 - 4 gadus veci bērniVingrinājumiFonētiskie traucējumiSkolas pedagoģijaRotaļa
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Stabilization of unilamellar catanionic vesicles induced by β-cyclodextrins: A strategy for a tunable drug delivery depot.

2018

The limited stability of catanionic vesicles has discouraged their wide use for encapsulation and controlled release of active substances. Their structure can easily break down to form lamellar phases, micelles or rearrange into multilamellar vesicles, as a consequence of small changes in their composition. However, despite the limited stability, catanionic vesicles possess an attractive architecture, which is able to efficiently encapsulate both hydrophobic and hydrophilic molecules. Therefore, improving the stability of the vesicles, as well as the control on unilamellar structures, are prerequisites for their wider application range. This study focuses on the impact of β-cyclodextrins fo…

3003DepotPharmaceutical Science02 engineering and technology010402 general chemistry01 natural sciencesMicelleDiffusionSurface-Active AgentsDrug Delivery SystemsCyclodextrinLamellar structureUnilamellar Liposomeschemistry.chemical_classificationCatanionic vesiclesCyclodextrinChemistryCetrimoniumVesiclebeta-Cyclodextrinstechnology industry and agricultureTemperatureSodium Dodecyl SulfateCatanionic vesicles; Cyclodextrin; Diffusion; NMR; Self-assembly; 3003Self-assembly021001 nanoscience & nanotechnologyCatanionic vesicleControlled releaseNMR0104 chemical sciencesChemical engineeringSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoDrug deliveryCetrimonium Compoundslipids (amino acids peptides and proteins)Self-assembly0210 nano-technologyInternational journal of pharmaceutics
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Synchronizing the release rates of salicylate and indomethacin from degradable chitosan hydrogel and its optimization by definitive screening design.

2018

Abstract Three types of ionically crosslinked (with citric acid) chitosan discs were loaded with the highly water- soluble drug, sodium salicylate (SS) and the poorly water-soluble drug, indomethacin (Ind). In separate experiments the hydrated discs were immersed in a de-crosslinking solution comprising of different concentrations of calcium chloride, which induced a controlled erosion of the discs, a process which was optimized to synchronize the release rates of the two drugs over a predetermined period of time. The optimization was accomplished by manipulating six factors: chitosan MW, its amount in the formulation, the concentration of the crosslinker agent, the concentration of the de-…

3003DrugSynchronized release ratemedia_common.quotation_subjectIndomethacinPharmaceutical Sciencechemistry.chemical_elementmacromolecular substances02 engineering and technologyCalciumTriggered erosionCitric AcidChitosan03 medical and health scienceschemistry.chemical_compoundCrosslinked chitosan0302 clinical medicineDrug Delivery SystemsScreening designMultifactorial definitive screening designDissolutionSodium salicylatemedia_commonChitosanChromatographytechnology industry and agricultureHydrogelsCrosslinked chitosanDual drug platform021001 nanoscience & nanotechnologyDrug LiberationCross-Linking Reagentschemistry030220 oncology & carcinogenesisDrug Design0210 nano-technologyCitric acidSalicylic AcidEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
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Nanoparticles of a polyaspartamide-based brush copolymer for modified release of sorafenib: In vitro and in vivo evaluation.

2017

Abstract In this paper, we describe the preparation of polymeric nanoparticles (NPs) loaded with sorafenib for the treatment of hepatocellular carcinoma (HCC). A synthetic brush copolymer, named PHEA-BIB-ButMA (PBB), was synthesized by Atom Trasnfer Radical Polymerization (ATRP) starting from the α-poly( N -2-hydroxyethyl)- d , l -aspartamide (PHEA) and poly butyl methacrylate (ButMA). Empty and sorafenib loaded PBB NPs were, then, produced by using a dialysis method and showed spherical morphology, colloidal size, negative ζ potential and the ability to allow a sustained sorafenib release in physiological environment. Sorafenib loaded PBB NPs were tested in vitro on HCC cells in order to e…

3003MaleHepatocellular carcinomamedicine.medical_treatmentPharmaceutical Science02 engineering and technologyATRPPharmacology01 natural sciencesDrug Delivery SystemsCopolymerChemistryATRP; Hepatocellular carcinoma; Sorafenib; Tumor targeting; α-Poly(N-2-hydroxyethyl)-DL-aspartamide; 3003Liver NeoplasmsSorafenib021001 nanoscience & nanotechnologyDrug delivery0210 nano-technologymedicine.drugSorafenibNiacinamideCarcinoma HepatocellularCell SurvivalRadical polymerizationIntraperitoneal injectionL-aspartamideMice NudeAntineoplastic AgentsEnhanced permeability and retention effect010402 general chemistryPolymethacrylic AcidsIn vivoCell Line TumormedicineAnimalsHumansneoplasmsProtein Kinase InhibitorsPhenylurea Compoundstechnology industry and agriculturedigestive system diseasesIn vitro0104 chemical sciencesDrug LiberationTumor targetingDelayed-Action PreparationsBiophysicsα-Poly(N-2-hydroxyethyl)-DNanoparticlesα-Poly(N-2-hydroxyethyl)-DL-aspartamidePeptidesJournal of controlled release : official journal of the Controlled Release Society
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The New "Maximum Yield Grid" (MYG) Array in Full 3D Resistivity Tomography

2008

Over the past few years geoelectrical prospecting has experienced many innovations, ranging from instrumental refinements to improvement of data interpretation. The consequence of this has been a strong increase in the method s resolution power and, therefore, its field of application has broadened. Nevertheless, the diffusion of 3D surveys in electrical resistivity tomography has been very much limited by the long acquisition time required by this kind of investigation, as compared to 2D ERT or other geophysical exploration methods like GPR. However, 3D ERT has a great advantage in terms of resolution power, that is very important in many applications, such as archeological or cultural her…

3D Electrical Resistivity Tomography MYG ArrayYield (engineering)Electrical resistivity and conductivitySettore GEO/11 - Geofisica ApplicataNuclear engineeringElectronic engineeringTomographyGridGeologyNear Surface 2008 - 14th EAGE European Meeting of Environmental and Engineering Geophysics
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Vingrinājumu sistēma priekšējo mēleņu (spraudzeņu [R], [L]) izrunas traucējumu novēršanai 5 – 6 gadus veciem bērniem

2021

Diplomdarba tēma “ Vingrinājumu sistēma priekšējo mēleņu (spraudzeņu [R], [L]) izrunas traucējumu novēršanai 5 – 6 gadus veciem bērniem”. Diplomdarba autore Inese Glīzdeniece. Diplomdarba vadītāja doc., Dr. paed. Ilze Šūmane. Darba saturs – kopīgais lappušu skaits 98 lpp., 33 pielikumi, 15 tabulas, 21 attēls, 48 izmantotā literatūra un avoti. Diplomdarbā apkopota teorija par 5 – 6 gadus vecu bērnu vispārējo un runas attīstību, kā arī priekšējo mēleņu [R] un [L] logopēdiskā analīze, runas un artikulācijas aparāta uzbūvi, smalkās un lielās motorikas attīstību 5 – 6 gadus veciem bērniem. Diplomdarbā apkopota vingrinājumu sistēma artikulācijas aparātam, smalkajai un lielajai motorikai, kura, iz…

5 - 6 gadus veci bērnilielā motorikaPedagoģijapriekšējie mēleņivingrinājumu sistēmasmalkā motorika
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