Search results for "GRI"

showing 10 items of 10209 documents

Inhibition of induced DNA oxidative damage by beers: correlation with the content of polyphenols and melanoidins.

2005

Beers are a source of dietary flavonoids; however, there exist differences in composition, alcohol concentration, and beneficial activities. To characterize these differences, three kinds of lager beer of habitual consumption in Spain, dark, blond, and alcohol-free, were assayed for total phenolic content, antioxidant activity, superoxide and hydroxyl radical scavenging activities, and in vitro inhibitory effect on DNA oxidative damage. Furthermore, their melanoidin content and correlation with antioxidant activity were evaluated. Dark beer contained the highest total phenolic (489 +/- 52 mg/L) and melanoidin (1.49 +/- 0.02 g/L) contents with a 2-fold difference observed when compared to th…

AntioxidantPolymersmedicine.medical_treatmentAntioxidantschemistry.chemical_compoundPhenolsSuperoxidesmedicineFood sciencePhenolsFlavonoidsChemistrySuperoxideDeoxyriboseHydroxyl RadicalMelanoidinfood and beveragesBeerPolyphenolsGeneral ChemistryFree Radical ScavengersBiochemistryDeoxyribosePolyphenolHydroxyl radicalComposition (visual arts)General Agricultural and Biological SciencesOxidation-ReductionDNA DamageJournal of agricultural and food chemistry
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Salmon (Salmo salar) side streams as a bioresource to obtain potential antioxidant peptides after applying pressurized liquid extraction (PLE)

2021

The pressurized liquid extraction (PLE) technique was used to obtain protein extracts with antioxidant capacity from salmon muscle remains, heads, viscera, skin, and tailfins. A protein recovery percentage ≈28% was obtained for all samples except for viscera, which was ≈92%. These values represented an increase of 1.5–4.8-fold compared to stirring extraction (control). Different SDS-PAGE profiles in control and PLE extracts revealed that extraction conditions affected the protein molecular weight distribution of the obtained extracts. Both TEAC (Trolox equivalent antioxidant capacity) and ORAC (oxygen radical antioxidant capacity) assays showed an outstanding antioxidant activity for viscer…

AntioxidantQH301-705.5Electrospray ionizationmedicine.medical_treatmentSalmo salarTrolox equivalent antioxidant capacityPharmaceutical ScienceAquacultureantioxidant capacityMass spectrometry01 natural sciencesAntioxidantsChemistry Techniques AnalyticalMass SpectrometryArticle0404 agricultural biotechnologyMetals HeavymycotoxinsDrug Discoverypressurized liquid extractionPressuremedicineAnimalsFish Proteins DietarySalmoBiology (General)heavy metalsPharmacology Toxicology and Pharmaceutics (miscellaneous)Polyacrylamide gel electrophoresischemistry.chemical_classificationChromatographybiologyChemistryside streams010401 analytical chemistryExtraction (chemistry)Computational Biologysalmon04 agricultural and veterinary sciencesbiology.organism_classification040401 food science0104 chemical sciencesAmino acidMolecular WeightpeptidesElectrophoresis Polyacrylamide GelproteinChromatography LiquidSDS-PAGEMarine Drugs
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Use of Saccharomyces cerevisiae and Caenorhabditis elegans as model organisms to study the effect of cocoa polyphenols in the resistance to oxidative…

2011

Developing functional foods to improve the quality of life for elderly people has great economic and social impact. Searching for and validating ingredients with in vivo antioxidant effects is one of the key steps in developing this kind of food. Here we describe the combined use of simple biological models and transcriptomics to define the functional intracellular molecular targets of a polyphenol-enriched cocoa powder. Cocoa powder supplemented culture medium led to increased resistance to oxidative stress, in both the budding yeast Saccharomyces cerevisiae and the nematode Caenorhabditis elegans, and, in the latter, lifespan was also increased. These effects are fully dependent on the po…

AntioxidantSaccharomyces cerevisiae Proteinsmedicine.medical_treatmentSaccharomyces cerevisiaeGene ExpressionSaccharomyces cerevisiaemedicine.disease_causeModels BiologicalAntioxidantsHistone DeacetylasesIngredientFunctional foodPhenolsFunctional FoodmedicineAnimalsSirtuinsFood scienceCaenorhabditis elegansCaenorhabditis elegans ProteinsCaenorhabditis elegansFlavonoidsCacaobiologybusiness.industryfood and beveragesPolyphenolsForkhead Transcription FactorsGeneral Chemistrybiology.organism_classificationYeastBiotechnologyCulture MediaOxidative StressPolyphenolGeneral Agricultural and Biological SciencesbusinessOxidative stressTranscription FactorsJournal of agricultural and food chemistry
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Extraction of polyphenols in Himanthalia elongata and determination by high performance liquid chromatography with diode array detector prior to its …

2016

Abstract Several studies have demonstrated the antioxidant capacity of seaweeds, which can be used for the development of biopharmaceuticals with extensive medical application. Antioxidant therapies appear to attenuate the organic deterioration originated by an excessive oxidative stress, which could prevent the harmful effects of various injuries such as ischemia-reperfusion (I/R) among others. Marine brown seaweeds play a significant role, as they are the only organisms on earth producing phlorotannins, which are polyphenols that exhibit important biological activity. To ensure obtaining an extract with the greatest antioxidant activity, some variables that affect the extraction of polyph…

AntioxidantTime Factorsmedicine.medical_treatmentClinical BiochemistryPhaeophytaBiochemistryAntioxidantsAnalytical Chemistrychemistry.chemical_compound0404 agricultural biotechnologyChlorogenic acidLimit of DetectionmedicineCaffeic acidGallic acidGentisic acidChromatography High Pressure LiquidChromatography Reverse-PhaseChromatographyTemperaturefood and beveragesPolyphenolsReproducibility of ResultsCatechin04 agricultural and veterinary sciencesCell BiologyGeneral MedicineFree Radical ScavengersSeaweed040401 food scienceOxidative StresschemistryPolyphenolCalibrationMyricetinJournal of chromatography. B, Analytical technologies in the biomedical and life sciences
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Effect of high levels of CO 2 on the electrochemical behavior and the enzymatic and non‐enzymatic antioxidant systems in black and white table grapes…

2019

[Bakghround]: In this study, we analyzed the effect of the application of high levels of CO2 (20 kPa CO2  + 20 kPa O2  + 60 kPa N2 ) for 3 days at low temperature on a white table-grape cultivar (Superior Seedless) in comparison with a black one (cv. Autumn Royal) in terms of quality parameters. We also used a solid-state voltammetry methodology to analyze the effect of the 3-day gaseous treatment in berry tissues from both cultivars in the first stage of storage. We determined the role of the non-enzymatic (total phenols, total anthocyanins, and antioxidant activity) and the enzymatic antioxidant (catalase (GCAT), ascorbate peroxidase (VcAPX) gene expression) systems in the behaviors of bo…

AntioxidantTotal phenolics030309 nutrition & dieteticsTotal anthocyaninsmedicine.medical_treatmentBerryengineering.material03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologymedicineFood sciencePhenolsCultivar0303 health sciencesNutrition and DieteticsbiologyPulp (paper)fungiTable grapeSolid state voltammetryfood and beverages04 agricultural and veterinary sciencesCatalase040401 food sciencechemistryCatalaseVitis viniferabiology.proteinengineeringAscorbate peroxidaseAgronomy and Crop ScienceFood ScienceBiotechnologyPeroxidaseJournal of the Science of Food and Agriculture
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Molecular Characterization of White Wines Antioxidant Metabolome by Ultra High Performance Liquid Chromatography High-Resolution Mass Spectrometry

2020

International audience; The knowledge about the molecular fraction contributing to white wines oxidative stability is still poorly understood. However, the role of S- and N-containing compounds, like glutathione and other peptides, as a source of reductant in many oxidation reactions, and acting against heavy metals toxicity, or lipid and polyphenol oxidation as ROS-scavenger is today very well established. In that respect, the aim of the present study is to introduce an original analytical tool for the direct determination of the available nucleophilic compounds in white wine under acidic pH conditions. One step derivatization of nucleophiles has been realized directly in wines using 4-met…

AntioxidantUHPLC-QqTOF-MSPhysiologymedicine.medical_treatmentClinical BiochemistrynucleophilesMass spectrometry01 natural sciencesBiochemistryArticlechemistry.chemical_compound0404 agricultural biotechnologymedicineMetabolomeDerivatizationuntargeted analysisMolecular BiologyMETLINthiolsWineChromatographyChardonnay wine oxidationChemistry010401 analytical chemistrylcsh:RM1-950food and beverages04 agricultural and veterinary sciencesCell Biology040401 food science0104 chemical sciencesQuinonelcsh:Therapeutics. PharmacologyPolyphenolpeptides[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Chemical Profiling of Polyfloral Belgian Honey: Ellagic Acid and Pinocembrin as Antioxidants and Chemical Markers

2017

Chemical profiling of northern Belgian polyfloral honeys was performed to analyse their phenolic compound content (flavonoids and phenolic acids). First, samples were subjected to a standard analysis of their physicochemical properties, and then, the phenolic fraction was isolated and analysed using a HPLC/PAD method. All of the tested honeys showed a common and specific phenolic profile that could be the basis for the differentiation of polyfloral honeys of the Antwerp region from other polyfloral honeys. Chromatographic data indicated a high content of ellagic acid (9.13–13.66 mg/100 g honey), as well as the flavonoid pinocembrin (1.60–1.85 mg/100 g honey) in these honeys. Ellagic acid, a…

Antioxidantanimal structuresArticle SubjectDPPHmedicine.medical_treatmentFlavonoid01 natural sciencesHigh-performance liquid chromatographylcsh:Chemistrychemistry.chemical_compound0404 agricultural biotechnologyChemical markermedicineFood scienceChemical compositionchemistry.chemical_classificationPinocembrinChemistry010401 analytical chemistrydigestive oral and skin physiologyfungifood and beverages04 agricultural and veterinary sciencesGeneral Chemistry040401 food science0104 chemical scienceslcsh:QD1-999behavior and behavior mechanismsEllagic acidJournal of Chemistry
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Antioxidant Properties of a Supercritical Fluid Extract of the Halophyte Mesembryanthemum nodiflorum L. from Sicilian Coasts: Nutraceutical and Cosme…

2020

The aim of this paper was to obtain different extracts from the aerial parts of Mesembryanthemum nodiflorum, comparing traditional extraction (using solvents with increasing polarity such as hexane, ethanol 80%, acetone 70% and water) with an eco-friendly technique (supercritical fluid extraction (SFE))

AntioxidantantioxidantDPPHmedicine.medical_treatmentice plant01 natural sciencesSFEIntegrin 1lcsh:Technologylcsh:Chemistry03 medical and health scienceschemistry.chemical_compoundNutraceuticalSettore AGR/20 - Zoocolturemedicineoxidative stressGeneral Materials ScienceMesembryanthemum nodiflorumFood scienceInstrumentationlcsh:QH301-705.5030304 developmental biologyFluid Flow and Transfer Processes0303 health sciencescell cultureSirt1biologyChemistrylcsh:TProcess Chemistry and TechnologyExtraction (chemistry)General EngineeringSupercritical fluid extractionIntegrin α1biology.organism_classificationlcsh:QC1-9990104 chemical sciencesComputer Science Applications010404 medicinal & biomolecular chemistrylcsh:Biology (General)lcsh:QD1-999Polyphenollcsh:TA1-2040Oxidative strelcsh:Engineering (General). Civil engineering (General)Cosmeceuticallcsh:PhysicsApplied Sciences
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Accelerated Solvent Extraction and Pulsed Electric Fields for Valorization of Rainbow Trout (Oncorhynchus mykiss) and Sole (Dover sole) By-Products: …

2021

Fishery by-products are rich in biologically active substances and the use of green and efficient extraction methods to recover these high-added-value compounds is of particular importance. In this study, head, skin and viscera of rainbow trout and sole were used as the target matrices and accelerated solvent extraction (ASE) (45–55 °C, 15 min, pH 5.2–6.8, 103.4 bars) and pulsed electric fields (PEF) (1–3 kV/cm, 123–300 kJ/kg, 15–24 h) were applied as extraction technologies. The results showed that ASE and PEF significantly increased the protein extract efficiency of the fish by-products (p < 0.05) by up to 80%. SDS-PAGE results showed that ASE and PEF treatments changed the molecular size…

AntioxidantantioxidantTime FactorsOxygen radical absorbance capacityFood Handlingmedicine.medical_treatmentPharmaceutical ScienceChemical Fractionation01 natural sciencesAntioxidantschemistry.chemical_compoundDover soleElectricityDrug DiscoveryFood sciencelcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Polyacrylamide gel electrophoresisABTSTemperature04 agricultural and veterinary sciencesHydrogen-Ion Concentration040401 food science6. Clean waterOncorhynchus mykissFlatfishesMolar mass distributionElectrophoresis Polyacrylamide GelAntioxidantFish Proteinsanimal structuresFish by-productsArticleASE0404 agricultural biotechnologyfoodmedicinePressureAnimals14. Life underwaterWaste Productsfish by-productsOxygen Radical Absorbance CapacityProtein010401 analytical chemistryExtraction (chemistry)PEFfood.food0104 chemical sciencesMolecular Weightlcsh:Biology (General)chemistrySeafoodSolventsRainbow troutproteinSDS-PAGE
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Ultrasonically-Assisted and Conventional Extraction from Erodium Glaucophyllum Roots Using Ethanol:Water Mixtures: Phenolic Characterization, Antioxi…

2020

The paper presents experimental results concerning the ultrasonically-assisted extraction of bioactive compounds from Erodium glaucophyllum roots. A comparison with conventional methodology is presented, and thereby the phytochemical composition and the antioxidant and anti-inflammatory activities of extracts are evaluated. The phenolic profile of Erodium extracts was analyzed by TOF&ndash

Antioxidantantioxidantmedicine.medical_treatmentAnti-Inflammatory AgentsPharmaceutical Science02 engineering and technologyPlant RootsAntioxidantsAnalytical Chemistrychemistry.chemical_compoundDrug DiscoverySolid phase extractionCarotenoidChromatography High Pressure Liquidanti-inflammatorychemistry.chemical_classificationbiologyChemistryultrasound04 agricultural and veterinary sciences021001 nanoscience & nanotechnology040401 food scienceUltrasonic WavesChemistry (miscellaneous)Molecular MedicineAntioxidant0210 nano-technologysolid-liquid extractionErodiumPolyphenolTECNOLOGIA DE ALIMENTOSmedicine.drug_classAnti-inflammatoryArticlelcsh:QD241-4410404 agricultural biotechnologylcsh:Organic chemistryPhenolsUltrasoundmedicinePhysical and Theoretical ChemistryChromatographyEthanolPlant ExtractsOrganic ChemistryExtraction (chemistry)Solid-liquid extractionbiology.organism_classificationpolyphenolTracheophytaPolyphenolSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationTroloxAnti-inflammatoryChromatography LiquidMolecules
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