Search results for "GYNAECOLOGY"

showing 10 items of 122 documents

Progestogens to prevent preterm birth in twin pregnancies:an individual participant data meta-analysis of randomized trials

2012

Abstract Background Preterm birth is the principal factor contributing to adverse outcomes in multiple pregnancies. Randomized controlled trials of progestogens to prevent preterm birth in twin pregnancies have shown no clear benefits. However, individual studies have not had sufficient power to evaluate potential benefits in women at particular high risk of early delivery (for example, women with a previous preterm birth or short cervix) or to determine adverse effects for rare outcomes such as intrauterine death. Methods/design We propose an individual participant data meta-analysis of high quality randomized, double-blind, placebo-controlled trials of progestogen treatment in women with …

Adultmedicine.medical_specialtyReproductive medicine/dk/atira/pure/subjectarea/asjc/2700/2729lcsh:Gynecology and obstetricslaw.inventionStudy ProtocolClinical ProtocolsRandomized controlled trialPregnancylawObstetrics and GynaecologymedicineHumansAdverse effectTwin Pregnancylcsh:RG1-991Randomized Controlled Trials as TopicPregnancyModels StatisticalObstetricsbusiness.industryIndividual participant dataInfant NewbornPregnancy OutcomeObstetrics and Gynecologymedicine.diseasePregnancy ComplicationsPremature birthMeta-analysisPregnancy TwinPremature BirthFemaleProgestinsbusiness
researchProduct

Data comparison between pharmacological induction of labour and spontaneous delivery. A single centre experience.

2016

Objectives: To assess the differences in the maternal and fetal outcomes between pharmacological induced and sponta­neous labour in nulliparous women. Material and methods: Observational cohort study carried out over a period of 2 years. Inclusion criteria: nulliparous sin­gleton pregnancies, with cephalic fetal presentation, elective labour induction with intra-vaginal prostaglandin E2 (PGE2) gel (Prepidil® 2 mg) at a gestational age of 41 weeks. Control group: patients who entered labour spontaneously at a gestational age of ≥ 40 weeks. The main demographic maternal characteristics and intra- and postpartum data were extracted from computer records and obstetrics diaries and were used for…

Adultmedicine.medical_specialtyTime FactorsProstaglandin E2Cohort Studies03 medical and health sciences0302 clinical medicineObstetrics and gynaecologyPregnancy030225 pediatricsSpontaneous labourOxytocicsInduction of labourMedicineInduction of labour Neonatal outcome Prostaglandin E2 Spontaneous labour Medicine (all) Obstetrics and GynecologyHumans030212 general & internal medicineLabor InducedProstaglandin E2reproductive and urinary physiologyGynecologyFetusbusiness.industryObstetricsInfant NewbornPregnancy OutcomeObstetrics and GynecologyGestational ageSpontaneous labourFetal PresentationNeonatal outcomeDelivery ObstetricSingle centreProstaglandinsFemalebusinessCohort studymedicine.drugGinekologia polska
researchProduct

Growth factor concentrations and their placental mRNA expression are modulated in gestational diabetes mellitus: possible interactions with macrosomia

2009

Abstract Background Gestational diabetes mellitus (GDM) is a form of diabetes that occurs during pregnancy. GDM is a well known risk factor for foetal overgrowth, termed macrosomia which is influenced by maternal hypergycemia and endocrine status through placental circulation. The study was undertaken to investigate the implication of growth factors and their receptors in GDM and macrosomia, and to discuss the role of the materno-foeto-placental axis in the in-utero regulation of foetal growth. Methods 30 women with GDM and their 30 macrosomic babies (4.75 ± 0.15 kg), and 30 healthy age-matched pregnant women and their 30 newborns (3.50 ± 0.10 kg) were recruited in the present study. Serum …

Adultmedicine.medical_specialtyTunisiaendocrine system diseasesOffspringPlacentalcsh:Gynecology and obstetricsFetal MacrosomiaReceptor Platelet-Derived Growth Factor betaGrowth factor receptorEpidermal growth factorPregnancyPlacentaDiabetes mellitusInternal medicineResearch articleObstetrics and GynaecologyFetal macrosomiamedicineHumansRNA MessengerInsulin-Like Growth Factor Ilcsh:RG1-991PregnancyEpidermal Growth Factorbusiness.industryInfant NewbornObstetrics and Gynecologynutritional and metabolic diseasesmedicine.diseasefemale genital diseases and pregnancy complicationsUp-RegulationGestational diabetesDiabetes Gestationalmedicine.anatomical_structureEndocrinologyInsulin-Like Growth Factor Binding Protein 3Case-Control StudiesGrowth HormoneIntercellular Signaling Peptides and ProteinsFemaleFibroblast Growth Factor 2businessBMC Pregnancy and Childbirth
researchProduct

Laparoscopic pelvic lymphadenectomy in 32 pregnant patients with cervical cancer: Rationale, description of the technique, and outcome

2014

ObjectiveIndividualized treatment of pregnant patients with cervical cancer is mandatory; hence, information on nodal status is pivotal to allow a waiting strategy in early-stage disease.We aimed to verify the oncological safety and surgical reproducibility of a standardized laparoscopic pelvic lymphadenectomy in pregnant patients with cervical cancer.MethodsWe standardized laparoscopic pelvic lymphadenectomy during the first and second term of gestation in 32 patients with cervical cancer since 1999. According to gestational week (GW) of less than 16 GWs or more than 16 GWs, 2 different techniques were used.ResultsThe International Federation of Gynecology and Obstetrics stages were IA in …

Adultmedicine.medical_specialtyUterine Cervical NeoplasmStagingPelvimedicine.medical_treatmentUterine Cervical NeoplasmsPelvisObstetrics and gynaecologyPregnancyLaparotomymedicineHumansLaparoscopyLymph nodePelvisNeoplasm StagingCervical cancerPregnancymedicine.diagnostic_testbusiness.industryLymph NodeObstetrics and GynecologyLymphadenectomymedicine.diseaseSurgeryPregnancy Trimester Firstmedicine.anatomical_structureOncologyPregnancy Trimester SecondCervical cancerLymph Node ExcisionLymphadenectomyLaparoscopyFemaleLymph NodesbusinessPregnancy Complications NeoplasticHuman
researchProduct

Laparoscopic radical hysterectomy in cervical cancer as total mesometrial resection (L-TMMR): A multicentric experience

2015

Abstract Objective To analyze the feasibility of total mesometrial resection by laparoscopy (L-TMMR) in a multicentric series of early stage cervical cancer. Method We prospectively evaluated a consecutive series of cervical cancer patients with pre-operative FIGO stages IA2–IB1 at the Catholic University in Rome and in Campobasso and the Charite University in Berlin. All cases were assessed at pre-operative MRI scan and clinically confirmed by investigation under anesthesia, adhering strictly to the FIGO criteria. The surgical and post-surgical data were collected. Results 104 women with cervical cancer were admitted between July 2013 and August 2014 and among them 71 patients with pre-ope…

Adultmedicine.medical_specialtyUterine Cervical Neoplasmmedicine.medical_treatmentFistulaUterine Cervical NeoplasmsCervical CancerHysterectomyObstetrics and gynaecologymedicineHumansHemoperitoneumProspective StudiesStage (cooking)Prospective cohort studyLaparoscopyTotal Mesometrial Resection (TMMR)AgedNeoplasm StagingCervical cancerHysterectomymedicine.diagnostic_testbusiness.industryMedicine (all)Obstetrics and GynecologyMiddle Agedmedicine.diseaseSurgeryProspective StudieSettore MED/40 - GINECOLOGIA E OSTETRICIAOncologyLymph Node ExcisionLaparoscopyFemalelaparososcopicmedicine.symptombusinessHuman
researchProduct

Therapeutic group psychoeducation and relaxation in treating fear of childbirth

2006

The increase in the numbers of women fearing childbirth and requesting cesarean sections call for new forms of antenatal treatment.Finnish nulliparous women experiencing severe fear of childbirth (experimental group, n = 102) attended 5 group sessions with a psychologist, once together with a midwife, during the third trimester. One session was held 3 months after the delivery. Each session consisted of a discussion of fear and feelings towards the impending birth and parenthood in a psychotherapeutic atmosphere and of relaxation exercises focused on an imaginary childbirth. The results were compared with those of 85 women treated for fear of childbirth by 2 appointments with an obstetricia…

Adultmedicine.medical_specialtymedicine.medical_treatmentmedia_common.quotation_subjectRelaxation TherapyThird trimesterObstetrics and gynaecologyPregnancymedicinePsychoeducationHumansChildbirthreproductive and urinary physiologymedia_commonRelaxation (psychology)Cesarean Sectionbusiness.industryObstetricsParturitionConventional treatmentObstetrics and GynecologyFearGeneral MedicineFeelingPsychotherapy GroupPhysical therapyFemalebusinessTherapeutic groupActa Obstetricia et Gynecologica Scandinavica
researchProduct

A multicenter study on the appropriateness of hospitalization in obstetric wards: application of Obstetric Appropriateness Evaluation Protocol (Obste…

2015

The cross-sectional study has been based on the implementation of the Obstetric Appropriateness Evaluation Protocol (OAEP) in seven hospitals to determine inappropriate hospital admissions and days of stay. The outcomes were: inappropriateness of admission and "percentage of inappropriateness" for one hospitalization. A total number of 2196 clinical records were reviewed. The mean percentage of inappropriateness for hospitalization was 22%. The percentage of inappropriateness for the first 10 d of hospitalization peaked in correspondence of the fourth (42%). The logistic regression model on inappropriated admission reported that emergency admission was a protective factor (OR = 0.4) and to …

Appropriateness evaluation protocol appropriateness of hospital use inappropriateness obstetricsAdultmedicine.medical_specialtyProtective factorappropriateness of hospital useLogistic regressionPediatricsRegional Health PlanningObstetrics and gynaecologyPregnancyAppropriatenesse valuation protocolAppropriateness evaluation protocol; Appropriateness of hospital use; Inappropriateness; ObstetricsHumansMulticenter Studies as TopicMedicineAppropriateness evaluation protocolRisk factorHospitals TeachingObstetrics and Gynecology Department HospitalinappropriatenessobstetricsEmergency admissionbusiness.industryObstetrics and GynecologyPerinatology and Child HealthLength of StayHospitalizationCross-Sectional StudiesOutcome and Process Assessment Health CareItalyMulticenter studyAppropriateness evaluation protocol; appropriateness of hospital use; inappropriateness; obstetrics; Pediatrics Perinatology and Child Health; Obstetrics and GynecologyPediatrics Perinatology and Child HealthEmergency medicineAppropriatenesse valuation protocol; appropriateness of hospital use; obstetrics; inappropriatenessFemalebusinessClinical recordThe Journal of Maternal-Fetal & Neonatal Medicine
researchProduct

Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM …

2020

Abstract Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pre…

COVID-19 VaccineInfectious Disease TransmissionPerinatal DeathAbortionClinical Laboratory TechniqueMiscarriageCohort Studies0302 clinical medicineCOVID-19 TestingPregnancyRisk Factors3123 Gynaecology and paediatricsSecondary analysisPerinatal medicineAbortion SpontaneouMedicineVertical030212 general & internal medicineViralPregnancy Complications Infectiouscoronavirus; perinatal morbidity; perinatal mortality; covid-19Coronavirus; perinatal morbidity; perinatal mortality; Abortion Spontaneous; COVID-19; COVID-19 Testing; COVID-19 Vaccines; Clinical Laboratory Techniques; Cohort Studies; Coronavirus Infections; Female; Gestational Age; Humans; Infant Newborn; Infant Premature; Infectious Disease Transmission Vertical; Pandemics; Pneumonia Viral; Pregnancy; Pregnancy Complications Infectious; Pregnancy Outcome; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; SARS-CoV-2; Betacoronavirus; Fetal Death; Perinatal Deathperinatal morbidity030219 obstetrics & reproductive medicineObstetricsReverse Transcriptase Polymerase Chain ReactionInfectiousPregnancy OutcomeGestational ageObstetrics and Gynecology3. Good healthSettore MED/40perinatal mortalityGestationFemaleCoronavirus InfectionsInfant PrematureHumanmedicine.medical_specialtyCOVID-19 VaccinesCoronavirus disease 2019 (COVID-19)CoronaviruPneumonia ViralSocio-culturaleGestational AgeIntrauterine deviceCoronavirus; perinatal morbidity; perinatal mortality03 medical and health sciencesBetacoronavirusPARVOVIRUS B19 INFECTIONCoronavirus perinatal morbidity perinatal mortalityHumansAdverse effectPrematurePandemicsFetal DeathPregnancyFetusBetacoronaviruPandemicCoronavirus Infectionbusiness.industryClinical Laboratory TechniquesSARS-CoV-2Risk FactorSpontaneousMORTALITYInfant NewbornAbortionCOVID-19InfantOdds ratioPneumoniamedicine.diseaseNewbornInfectious Disease Transmission VerticalAbortion SpontaneousPregnancy ComplicationsCoronavirusPediatrics Perinatology and Child HealthPregnancy Complications InfectiouCohort StudiebusinessCoronavirus; perinatal mortality; perinatal morbidityJournal of perinatal medicine
researchProduct

Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection

2021

WOS:000613461600006 PubMed ID: 32926494 Objectives To evaluate the maternal and perinatal outcomes of pregnancies affected by SARS-CoV-2 infection. Methods This was a multinational retrospective cohort study including women with a singleton pregnancy and laboratory-confirmed SARS-CoV-2 infection, conducted in 72 centers in 22 different countries in Europe, the USA, South America, Asia and Australia, between 1 February 2020 and 30 April 2020. Confirmed SARS-CoV-2 infection was defined as a positive result on real-time reverse-transcription polymerase chain reaction (RT-PCR) assay of nasopharyngeal swab specimens. The primary outcome was a composite measure of maternal mortality and morbidity…

COVID19medicine.medical_treatmentcoronavirus; COVID-19; infection; pregnancy; SARS-CoV-2Abortioninfectious diseaseslaw.inventionCohort Studies0302 clinical medicinelaw3123 Gynaecology and paediatricsPregnancyObstetrics and Gynaecology030212 general & internal medicinePregnancy Complications Infectious030219 obstetrics & reproductive medicineRadiological and Ultrasound TechnologyTransmission (medicine)ObstetricsPregnancy OutcomeObstetrics and GynecologyCOVID19; Coronavirus; SARS-COV-2; infection; pregnancy.General MedicineDisease 2019 Covid-19Intensive care unit3. Good healthHospitalizationIntensive Care UnitsMaternal MortalitySettore MED/40Radiology Nuclear Medicine and imagingGestationFemalepregnancycoronavirus Pandemics Pregnancy Pregnancy Complications Infectious Pregnancy Outcome Respiration Artificial Retrospective Studies SARS-CoV-2 COVID-19 Infant Newborn Intensive Care UnitsMaternal MortalityInfectionCohort studyAdultmedicine.medical_specialtyCOVID-19; SARS-CoV-2; coronavirus; infection; pregnancyNO03 medical and health sciencesmedicineHumansRadiology Nuclear Medicine and imagingPandemicsRetrospective StudiesMechanical ventilationPregnancybusiness.industrySARS-CoV-2Infant NewbornInfantCOVID-19Retrospective cohort studymedicine.diseaseRespiration ArtificialinfectionCoronaviruscoronaviruReproductive MedicinebusinessCOVID19; Coronavirus; SARS-COV-2; infection; pregnancy
researchProduct

A test of the effort equalization hypothesis in children with cerebral palsy who have an asymmetric gait.

2022

Healthy people can walk nearly effortlessly thanks to their instinctively adaptive gait patterns that tend to minimize metabolic energy consumption. However, the economy of gait is severely impaired in many neurological disorders such as stroke or cerebral palsy (CP). Moreover, self-selected asymmetry of impaired gait does not seem to unequivocally coincide with the minimal energy cost, suggesting the presence of other adaptive origins. Here, we used hemiparetic CP gait as a model to test the hypothesis that pathological asymmetric gait patterns are chosen to equalize the relative muscle efforts between the affected and unaffected limbs. We determined the relative muscle efforts for the ank…

CP-oireyhtymäMalePhysiologyKneesKnee JointsSkeletal Joints3123 Gynaecology and paediatricsSTRENGTHMedicine and Health Sciencesvoimantuotto (fysiologia)ChildMusculoskeletal SystemGaitFatigueMultidisciplinaryLOCOMOTIONCP-vammaisetQRliikuntarajoitteetAnkle JointskävelyBiomechanical PhenomenaaskeleetLegsMedicineFemalebiomekaniikkaAnatomyGait AnalysisWALKINGResearch ArticleAdolescentScienceeducationPOWERlapset (ikäryhmät)MOVEMENTSigns and SymptomsSpatio-Temporal AnalysisHumansKneeSPEEDMuscle SkeletalSkeletonBiological LocomotionCerebral PalsyAnklesBiology and Life SciencesasymmetriaBody LimbsJointsClinical MedicineAnklehuman activitiesPLoS ONE
researchProduct