Search results for "Generation"
showing 10 items of 3050 documents
WIDENING THE SCOPE OF NEXT GENERATION SEQUENCING APPLICATIONS IN PEDIATRIC MEDICAL GENETICS
2018
Advances in DNA sequencing technologies through Next Generation Sequencing (NGS) approaches have enabled genome-wide discovery of chromosomal copy-number variants and single-nucleotide changes. NGS technologies are rapidly expanding our ability to identify and better define disease-causing mutations and genotype-phenotype correlation. Pediatric patients may particularly benefit from the introduction of these new technologies. Pediatricians must keep up with all these new skills, both in their residency programs as well as in their continuing medical education programs.
Poly(alkylidenamines) dendrimers as scaffolds for the preparation of low-generation ruthenium based metallodendrimers
2011
The aim of this article is to highlight the use of nitrile-functionalized poly(alkylidenamines) dendrimers as building blocks for the preparation of low-generation ruthenium based cationic metallodendrimers having in view potential biomedical applications. Air-stable poly(alkylidenamines) nitrile dendrimers, peripherally functionalized with the ruthenium moieties [Ru(η5-C5H5)(PPh3)2]+ or [RuCl(dppe)2]+, have been prepared, characterized and are being studied for their anticancer activity. The followed strategy is based on the biological advantages associated with low-generation dendrimers, the known activity of ruthenium compounds as anticancer drugs and the stability of these dendrimers at…
Non-cooperative game theory based stepwise power tariff model using Monte-Carle simulation for agricultural consumers
2019
Abstract In the present study the concept of non-cooperative game theory is proposed in the retail electricity market for introducing stepwise power tariff model (SPT) for agricultural consumers. The objective of the paper is to increase the energy generation through green energy generation sources (GEGS), introduction of plug-in hybrid electric vehicles, education of families, standard wiring and appliance efficiency in tariffs for agricultural consumers with non-cooperative game theory. Agricultural consumers are able to generate a huge amount of electricity through GEGS and are able to control the consumption in their own way, and the non-cooperative game theory is introduced. Energy con…
Nanopatterned ferroelectric crystals for parametric generation
2006
We report on recent results by surface periodic poling on lithium niobate and lithium tantalate. Such approach allows periodic inversion of the second order susceptibility with nanoscale features using insulating masks. We achieved a world-best 200 nm feature size, as well as good compatibility with alpha-phase proton exchanged channel waveguides in lithium niobate. Preliminary results of surface periodic poling in lithium tantalate also show similar characteristics. Surface poling is best suited for integrated optics devices in technologically-demanding configurations such as backward second harmonic generation and counter propagating optical parametric amplification
Exploring titanium dioxide as a new photonic platform
2019
International audience; We report the development of titanium dioxide-based waveguides for applications in the near-and mid-infrared. Thanks to embedded metal grating couplers, we demonstrate error free 10 Gbit/s optical transmissions at 1.55 and 2 µm. We also demonstrate octave-spanning supercontinuum in cm-long waveguides. We explore the way to improve such waveguides through optimized fabrication process.
Nonlinear Microwave Spectrometer for Investigating High-Tc Superconductors
2000
We describe a nonlinear microwave spectrometer, which can be conveniently used for investigating the harmonic generation at microwave frequencies in high-Tc superconductors. The use of this technique allows highlighting mechanisms responsible for the nonlinear microwave response of high-Tc superconductors as well as measuring specific characteristics of the investigated samples. We report a brief review of the main results obtained.
GENERAZIONE DI SECONDA ARMONICA RETRO-PROPAGANTE IN NIOBATO DI LITIO CON POLING PERIODICO
2010
We report on backward second-harmonic-generation in bulk periodically poled congruent lithium niobate with a 3.2 micron period. A tunable continuous-wave Ti:Sapphire laser allowed us exciting two resonant quasi-phase-matched orders. Resonances were also resolved by temperature tuning.
Guided-wave frequency doubling in surface periodically poled lithium niobate: competing effects
2007
We carried out second-harmonic generation in quasi-phase-matched ? -phase lithium niobate channel waveguides realized by proton exchange and surface periodic poling. Owing to a limited ferroelectric domain depth, we could observe the interplay between second-harmonic generation and self-phase modulation due to cascading and cubic effects, resulting in a nonlinear resonance shift. Data reduction allowed us to evaluate both the quadratic nonlinearity in the near infrared as well as the depth of the uninverted domains. © 2007 Optical
Wavelength tuning of femtosecond pulses generated in nonlinear crystals by using diffractive lenses
2010
We demonstrate that diffractive lenses (DLs) can be used as a simple method to tune the central wavelength of femtosecond pulses generated from second-order nonlinear optical processes in birefringent crystals. The wavelength tunability is achieved by changing the relative distance between the nonlinear crystal and the DL, which acts in a focusing configuration. Besides the many practical applications of the so-generated pulses, the proposed method might be extended to other wavelength ranges by demonstrated similar effects on other nonlinear processes, such as high-order harmonic generation.
Scaling guidelines of a soliton-based power limiter for 2R-optical regeneration applications
2010
International audience; In this work, we report scaling rules for the design of an all-fibered soliton-based power limiter for reamplification and reshaping (2R) regeneration process. In particular, we propose general guidelines to fix the optimum fiber length and initial power of the regenerator. We quantitatively point out the optical power limiting effect of the device enabling a significant reduction of the amplitude jitter of a degraded signal. Influence of the initial level of amplitude jitter is discussed and the results are compared with a self-phase modulation-based configuration working in the normal dispersion regime. Realistic numerical simulations in the context of 160 Gbit/s s…