Search results for "Genetic Structures"
showing 10 items of 2107 documents
ChemInform Abstract: Syntheses of Polyfunctionalized Resveratrol Derivatives Using Wittig and Heck Protocols.
2012
In the modified Wittig reaction, Tms is used as a highly valuable protecting group of the phenolic functions of the starting arenes.
The bleaching efficacy of carbamide peroxide gels containing potassium nitrate desensitizer
2020
Background To evaluate the bleaching efficacy of at-home carbamide peroxide (CP) gels in two concentrations, containing or not a desensitizing agent. Material and methods Forty incisors were divided into four groups (n=10), according to gel concentrations (10% or 22%), and presence or not of 3% potassium nitrate in the gel. A thin layer of gel was applied to the buccal surface of each tooth for 2h/day for 4 weeks. Bleaching efficacy was measured using a spectrophotometer, and ∆E*ab, ∆E00 and ∆WID were calculated. Measurements were performed at baseline, 7, 14, 21, 28, and 35 days following the first gel application. Data were analyzed by two-way RM-ANOVA and Tukey's test (α=0.05). Results R…
Effect of the color of the intraocular lens on optical and visual quality
2014
Purpose: To analyze the optical quality of intraocular lenses (IOL) with an orange (PC440Y) and a yellow (SN60AT) filter, and correlate these results with the visual quality of patients with these implants. Setting: Fisabio Oftalmología Médica, Valencia, Spain. Design: Randomized prospective study. Materials and Methods: The IOL optical quality was determined using the modulation transfer function (MTF) and the spectral transmission. The visual quality of 87 eyes with cataract (51 with orange filter and 36 with yellow filter) was determined by best corrected visual acuity (BCVA) and contrast sensitivity function (CSF) under photopic and mesopic conditions. To analyze the results, we use a S…
Mediterranean coccolith ecobiostratigraphy since the penultimate Glacial (the last 145,000years) and ecobioevent traceability
2015
The Mediterranean Sea is a miniature ocean ideal to test the response of marine ecosystems to amplified orbital and suborbital climate changes. Here we present coccolith data from a Sardinia Channel gravity core (Arcose C_33) analysed over the last 145,000 years, with a mean resolution of about 900 years. The study highlights that regional phytoplankton assemblages underwent significant modifications between the penultimate glacial and the last interglacial, as well as between the last glacial and the Holocene. The N ratio palaeoproductivity index suggests reduced productivity levels and the development of a deep nutricline during the last interglacial and the Holocene. Within the last glac…
Chiroptical Phenomena in Reverse Micelles: The Case of (1R,2S)- Dodecyl (2-hydroxy-1-methyl-2-phenylethyl)dimethylammonium Bromide (DMEB)
2014
(1R,2S)-Dodecyl(2-hydroxy-1-methyl-2-phenylethyl)dimethylammonium bromide (DMEB) aggregates dispersed in carbon tetrachloride have been investigated by Fourier transform infrared (FT-IR), vibrational circular dichroism (VCD) and 1H nuclear magnetic resonance (NMR) spectroscopy at various surfactant concentration and water-to-surfactant molar ratio. Experimental data indicate that, even at the lowest investigated concentration and in absence of added water, DMEBmolecules associate in supramolecular assemblies. At higherDMEBconcentration the aggregates can confine watermolecules,making it plausible to think thatDMEB form reverse micelles and that watermolecules are quite uniformly distributed…
Exciton and multiexciton optical properties of single InAs/GaAs site-controlled quantum dots
2013
We have studied the optical properties of InAs site-controlled quantum dots (SCQDs) grown on pre-patterned GaAs substrates. Since InAs nucleates preferentially on the lithography motifs, the location of the resulting QDs is determined by the pattern, which is fabricated by local oxidation nanolithography. Optical characterization has been performed on such SCQDs to study the fundamental and excited states. At the ground state different exciton complex transitions of about 500 μeV linewidth have been identified and the fine structure splitting of the neutral exciton has been determined (≈65 μeV). The observed electronic structure covers the demands of future quantum information technologies.…
Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk
2019
Web spiders connect silk proteins, so-called spidroins, into fibers of extraordinary toughness. The spidroin N-terminal domain (NTD) plays a pivotal role in this process: it polymerizes spidroins through a complex mechanism of dimerization. Here we analyze sequences of spidroin NTDs and find an unusually high content of the amino acid methionine. We simultaneously mutate all methionines present in the hydrophobic core of a spidroin NTD from a nursery web spider’s dragline silk to leucine. The mutated NTD is strongly stabilized and folds at the theoretical speed limit. The structure of the mutant is preserved, yet its ability to dimerize is substantially impaired. We find that side chains of…
Systemic therapies for mucopolysaccharidosis: ocular changes following haematopoietic stem cell transplantation or enzyme replacement therapy - a rev…
2010
The management of mucopolysaccharidosis (MPS) is focused on the multi-organ, sometimes life-threatening, clinical manifestations that occur over time. In the past, the limited, symptom-based treatment options led physicians to adopt a palliative approach towards individual disease-associated complications. The availability of systemic treatments such as haematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy (ERT) has created a better prognosis for MPS patients, particularly when initiated early in life. As part of an integrated management approach, these therapies could be valuable in managing the ocular features that are present in many children with MPS. HSCT has b…
Protective coloration of European vipers throughout the predation sequence
2020
Antipredator adaptations in the form of animal coloration are common and often multifunctional. European vipers (genus Vipera) have a characteristic dorsal zigzag pattern, which has been shown to serve as a warning signal to potential predators. At the same time, it has been suggested to decrease detection risk, and to cause a motion dazzle or flicker-fusion effect during movement. We tested these hypotheses by asking whether (1) the zigzag pattern decreases detection risk and (2) the detection is dependent on the base coloration (grey or brown) or the snake's posture (coiled, basking form or S-shaped, active form). Additionally, (3) we measured the fleeing speed of adders, Vipera berus, an…
Visual Acuity and Contrast Sensitivity Depending from Keratoconus Apex Position
2017
Abstract Various studies have demonstrated that patients with keratoconus have significant loss of contrast sensitivity while its value varies in different studies. None of these studies has analysed reduced contrast sensitivity depending on the position of apex of corneal conus. Visual acuity and contrast sensitivity were evaluated for patients with keratoconus using the FrACT software. Contrast sensitivity was assessed at the following frequencies: 1, 3, 5, 7, 9, 11, 13, and 15 cycles per degree (cpd). Twenty-four eyes with keratoconus were analysed. Contrast sensitivity was significantly lower for patients with the apex at the centre compared with apex on the periphery both with (p = 0.0…