Search results for "Genetic Structures"
showing 10 items of 2107 documents
Altered cellular calcium responsiveness to insulin in normal and hypertensive pregnancy.
1996
Objective To investigate the glucose-independent calcium-related effects of insulin from subjects with normal and hypertensive pregnancies. Method We used lndo-l fluorescence spectroscopy to measure cytosolic free calcium levels (Cai) in peripheral blood mononuclear cells (PBM) from 17 women (aged 20-40 years), six nonpregnant controls (NPC), five pregnant normotensive (PNT) women and six pregnant hypertensive (PHT) women, before and 5, 30, 60, 120 and 180 min after in vitro incubation with 200 microU/ml insulin. Results Basal Cai levels were significantly higher in PHT women (175.2 +/- 18.8 nmol/l) than they were in NPC women (122.8 +/- 2.8 nmol/l) and PNT women (123.9 +/- 3.5 nmol/l). The…
Physical Activity, Incidence, and Progression of Age-Related Macular Degeneration: A Multicohort Study.
2022
Contains fulltext : 249581.pdf (Publisher’s version ) (Closed access) PURPOSE: To investigate the impact of physical activity (PA) on the incidence or progression of age-related macular degeneration (AMD) in the general population. DESIGN: Meta-analysis of longitudinal cohort studies. METHODS: We included 14,630 adults with no or early AMD at baseline from 7 population-based studies and examined associations of PA with AMD incidence and progression using multistate models (MSM) per study and subsequent random effects meta-analysis. Age effects were assessed using meta-regression. The main outcome measure was the hazard ratio (HR) for incident early or progression to late AMD. RESULTS: At ba…
Improvement of phonemic fluency following leftward prism adaptation.
2021
AbstractAnatomo functional studies of prism adaptation (PA) have been shown to modulate a brain frontal-parieto-temporal network, increasing activation of this network in the hemisphere ipsilateral to the side of prism deviation. This effect raises the hypothesis that left prism adaptation, modulating frontal areas of the left hemisphere, could modify subjects’ performance on linguistic tasks that map on those areas. To test this hypothesis, 51 healthy subjects participated in experiments in which leftward or rightward prism adaptation were applied before the execution of a phonemic fluency task, i.e., a task with strict left hemispheric lateralization onto frontal areas. Results showed tha…
Melatonin Content of Human Milk: The Effect of Mode of Delivery
2020
Objective: Cesarean section rates are increasing in developed countries and could be performed as an emergency or elective procedure. Our research aim was to determine whether elective cesarean sec...
Contrast sensitivity after implantation of toric iris-claw lenses in phakic eyes.
2004
Abstract Purpose: To evaluate the change in contrast sensitivity after implantation of the Verisyse toric phakic intraocular lens (IOL) (AMO) for the correction of myopia with astigmatism. Setting: Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany. Methods: Eighteen eyes had implantation of an iris-supported toric phakic IOL to correct myopia with astigmatism. The mean preoperative spherical equivalent was −12.65 diopters ± 3.6 (SD). The contrast sensitivity with best spectacle correction was determined before surgery and 3 months after surgery using the CSV-1000 HGT instrument (Vector Vision Inc.). Results: Three months after IOL implantation, the mean contrast sen…
Late onset of unilateral optic disk edema secondary to treatment with imatinib mesylate
2017
Key Clinical Message Prompt ophthalmology evaluation and immediate imatinib suspension should be suggested at any time of tyrosine kinase inhibitor therapy in patients with visual deficit, as it may be a clinical manifestation of optic disk edema, and suspension may help in prompt recovery.
A new approach for characterizing atmospheric aerosols from spectral values of their optical depth. A simulated case study.
2005
We are developing a new method to determine the spectral contribution to the aerosol optical depth due to each aerosol type. An aerosol type depends directly on the procedence of the particles (marine, continental, artic, etc) and it is formed by some different pure components (mineral, soot, soluble and insoluble particles, sulphate, etc). In order to separate these contributions it is necessary to have the spectral aerosol optical thickness and aerosol size distribution. We use this distribution function to identify the different components of aerosols allowing us to reconstruct the aerosol optical depth taking into account the contribution of each type of aerosol. The validation of the m…
“The sound of affect”: Age differences in perceiving valence and arousal in music and their relation to music characteristics and momentary mood
2018
Throughout life, music plays an important role in individuals’ everyday affective experiences. Previous findings suggest that preferences for, and perceptions of, music with distinct affective qualities might differ for individuals from different age groups. To date, however, evidence from age-comparative studies across adulthood is rare and little is known about the mechanisms that contribute to age differences in music perception. In an age-heterogeneous sample ranging from adolescence to old adulthood ( n = 50; 12–75 years), we investigated differences in affect perceptions of 147 sounds and 465 songs of various musical styles and dates of origin, as well as the respective roles of musi…
Senile cataract: a review on free radical related pathogenesis and antioxidant prevention
1990
Abstract Glutathione metabolism plays an essential role in the homeostasis of the lens. Thus, it is not surprising that experimental depletion of this substance leads to a process of lens disorganization similar to senile cataract and that in all types of irreversible cataract there is a decrease in the glutathione content of the lens. Therefore, it may be useful in preventive geriatrics to raise the glutathione concentration of the lens and, since glutathione monoethyl ester can cross the capsule and membranes of the lens, administration of this compound may be the treatment of choice. This could be complemented by long-term administration of small doses of acetylsalicylic acid, in the ear…
Mitochondrial Markers in Aging and Primary Open-Angle Glaucoma
2020
This review focuses on recent progress in understanding the role of mitochondrial markers in the context of mitochondrial dysfunction in glaucoma and discussing new therapeutic approaches to modulate mitochondrial function and potentially lead to improved outcomes in glaucoma.