Search results for "Genou"

showing 10 items of 610 documents

Assessment of Granger causality by nonlinear model identification: application to short-term cardiovascular variability.

2007

A method for assessing Granger causal relationships in bivariate time series, based on nonlinear autoregressive (NAR) and nonlinear autoregressive exogenous (NARX) models is presented. The method evaluates bilateral interactions between two time series by quantifying the predictability improvement (PI) of the output time series when the dynamics associated with the input time series are included, i.e., moving from NAR to NARX prediction. The NARX model identification was performed by the optimal parameter search (OPS) algorithm, and its results were compared to the least-squares method to determine the most appropriate method to be used for experimental data. The statistical significance of…

Biomedical EngineeringBlood PressureBivariate analysisDirectionalitySensitivity and SpecificitySurrogate dataFeedbackNonlinear parametric modelGranger causalityControl theoryHeart RateOptimal parameter searchStatisticsAnimalsHumansComputer SimulationPredictabilityHeart rate variabilityMathematicsNonlinear autoregressive exogenous modelCardiovascular regulationSystem identificationModels CardiovascularNonlinear systemAutoregressive modelNonlinear DynamicsAutoregressive exogenous modelSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaRegression AnalysisSurrogate dataArterial pressure variabilityAlgorithmsAnnals of biomedical engineering
researchProduct

An overview of doping in sports

2019

The history of doping field can be outlined in three major stages: (1) early stage in which drug abuse took place during sports performance and competition and gas chromatography was used for its detection; (2) approximately in the 1970s when androgenic anabolic steroids were introduced; (3) In the recent era when the fields of biochemistry, physiology, toxicology, genomics, genetics, immunology, and molecular biology were integrated and applied routinely. Advanced omics technology and gene doping age may be applied in near future. This review will discuss commonly abused materials, both their adverse and harmful effects, and the alleged benefits in conjunction with the current standards in…

Bioquímicaprotein synthesis[SDV]Life Sciences [q-bio]anabolic androgenic steroidsPharmacologyProtein chemistry01 natural sciencesDopaje03 medical and health sciencesCondensed Matter::Materials SciencePhysics::Popular PhysicsBlood dopingerythropoiesis-stimulating agentsGene dopinghuman urineCondensed Matter::SuperconductivityToxicologíaComputer Science::Multimediaaromatase inhibition030304 developmental biology0303 health sciencesAromatase inhibitionbody compositionChemistryexogenous growth hormone010401 analytical chemistryMedicina deportivaskeletal muscle massAnabolic-Androgenic SteroidsSkeletal muscle massGenética3. Good health0104 chemical sciencesautologous blood transfusionsCondensed Matter::Strongly Correlated Electronshuman activitiesClinical psychology
researchProduct

Forecast Output Coincidence and Biproportion: Two Criteria to Determine the Orientation of an Economy. Comparison for France (1980-1997)

2002

International audience; The method of forecast output coincidence used to determine if sectors are demand-sided or supply-sided in an input-output framework mixes two effects, the structural effect (choosing between demand and supply side models) and the effect of an exogenous factor (final demand or added-value). The note recalls that another method is possible, the comparison of the stability of technical and allocation coefficients, generalized by the biproportional filter: if for a sector, after biproportional filtering, column coefficients are more stable than row coefficients, then this sector is declared as not supply-sided (but one cannot decide that it is demand-sided anyway), and …

BiproportionEconomics and EconometricsJEL: C - Mathematical and Quantitative Methods/C.C6 - Mathematical Methods • Programming Models • Mathematical and Simulation Modeling/C.C6.C67 - Input–Output ModelsSupplyChangeJEL: D - Microeconomics/D.D5 - General Equilibrium and Disequilibrium/D.D5.D57 - Input–Output Tables and AnalysisStability (probability)Column (database)CoincidenceSupply and demandMicroeconomicsJEL: C - Mathematical and Quantitative Methods/C.C6 - Mathematical Methods • Programming Models • Mathematical and Simulation Modeling/C.C6.C63 - Computational Techniques • Simulation ModelingEconometricsEconomicsDemandJEL : D - Microeconomics/D.D5 - General Equilibrium and Disequilibrium/D.D5.D57 - Input–Output Tables and Analysis[ SHS.ECO ] Humanities and Social Sciences/Economies and finances[SHS.ECO] Humanities and Social Sciences/Economics and FinanceInput/outputJEL : C - Mathematical and Quantitative Methods/C.C6 - Mathematical Methods • Programming Models • Mathematical and Simulation Modeling/C.C6.C67 - Input–Output ModelsOrientation (computer vision)Exogenous factorFilter (signal processing)[SHS.ECO]Humanities and Social Sciences/Economics and FinanceJEL : C - Mathematical and Quantitative Methods/C.C6 - Mathematical Methods • Programming Models • Mathematical and Simulation Modeling/C.C6.C63 - Computational Techniques • Simulation ModelingInput-OutputRAS
researchProduct

Insulin resistance and endogenous digoxin-like factor in obese hypertensive patients with glucose intolerance

1992

Hypertensive obese subjects with glucose intolerance have hyperinsulinaemia, insulin resistance and intracellular cation imbalance resulting in increased sodium content. The aim of our study was to assess in these patients plasma levels of endogenous digoxin-like factor (EDLF), an inhibitor of the sodium-pump mechanism. We studied 14 hypertensive and 12 normotensive subjects with obesity and glucose intolerance for fasting blood glucose, and plasma insulin, C-peptide and EDLF levels: the two groups were matched for age and BMI and were studied after a 2-week wash-out period from hypotensive drugs. Compared with normotensives, hypertensive subjects had higher plasma insulin levels, a greater…

Blood GlucoseMaleDigoxinmedicine.medical_specialtyEndocrinology Diabetes and Metabolismmedicine.medical_treatmentEndogenyEndogenous digoxin-like factorEndocrinologyInsulin resistanceInternal medicineDiabetes mellitusInternal MedicineHumansInsulinMedicineObesityImmunoreactive insulinC-Peptidebusiness.industryInsulinBlood ProteinsGeneral MedicineGlucose Tolerance TestMiddle AgedSaponinsmedicine.diseaseObesityCardenolidesEndocrinologyHyperglycemiaHypertensionFemaleInsulin ResistanceSodium-Potassium-Exchanging ATPasebusinessIntracellularActa Diabetologica
researchProduct

Alternative method to treat oroantral communication and fistula with autogenous bone graft and platelet rich firbin

2016

Background Removing a tooth from the jaw results in the occurrence of oroantral communication in beneficial anatomic conditions or in the case of a iatrogenic effect. Popularized treatments of the oroantral communication have numerous faults. Large bone defect eliminates the chance to introduce an implant. Purpose of this work was assessment of the usefulness of autogenous bone graft and PRF in normal bone regeneration in the site of oroantral communication. Material and Methods Bone regeneration in the site of oroantral communication was assessed in 20 patients. Bone defects were supplemented autogenous bone graft from mental protuberance in 14 cases and from oblique line in 6 cases. The g…

Blood Plateletsmedicine.medical_specialtyBone RegenerationFistulaDentistryFibrin03 medical and health sciences0302 clinical medicinePlatelet-Rich FibrinmedicineHumansOroantral communicationOroantral FistulaBone regenerationGeneral DentistryAlternative methodsFibrinBone Transplantationbiologybusiness.industryResearchAutogenous bone graft030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Platelet-rich fibrinSurgeryOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASbiology.proteinSurgeryImplantOral Surgerybusiness
researchProduct

Heme oxygenase-1 induction and regulation in unstimulated mouse peritoneal macrophages

2003

Heme oxygenase-1 (HO-1) is a stress protein induced by a variety of stimuli in inflammatory cells. This study was set up to investigate the induction of this protein in unstimulated macrophages. Resident mouse peritoneal macrophages purified by adhesion and cultured in basal conditions strongly induced HO-1 in a time-dependent manner, with a peak at 20 hr. At the same time, low levels of nitrite accumulated in the culture medium and expression of nitric oxide synthase-2 (NOS-2) and NOS-3 protein was detected. Inhibition of NO production and/or NOS expression by incubating macrophages with different drugs inhibiting NOS activity or modulating the redox state of the cell, such as N-acetylcyst…

Blotting WesternInflammationNitric Oxidemedicine.disease_causeBiochemistryNitric oxideMicechemistry.chemical_compoundmedicineAnimalsMacrophageHemeCells CulturedPharmacologybiologyChemistryMembrane ProteinsEndogenous mediatorImmunohistochemistryCell biologyNitric oxide synthaseHeme oxygenaseBiochemistryEnzyme InductionHeme Oxygenase (Decyclizing)Macrophages Peritonealbiology.proteinNitric Oxide Synthasemedicine.symptomOxidation-ReductionHeme Oxygenase-1Oxidative stressBiochemical Pharmacology
researchProduct

Ecotourism in Bolivia : an ethnographical study of ecotourism impacts in Madidi National Park

2016

Master thesis development management - University of Agder 2016 The concepts of ecotourism are widely defined but it is often used as a marketing instrument in order to promote tourism businesses related to nature. Ecotourism experience a fast growth in world tourism industry and many developing countries are trying to use ecotourism as a tool to achieve sustainable development. Ecotourism provides many beneficiaries to local environments, economies and socio-cultural lives. However, ecotourism may as well have harmful effects on those involved. Still, ecotourism conserves and protects local areas and its people. Madidi National Park in Bolivia has been estimated to be one of the world’s mo…

Boliviatourism impactspotentialsecotourismMadidi National Parksustainable developmentUT503VDP::Social science: 200::Social anthropology: 250indigenous communitieschallengesrainforest
researchProduct

Acetylcholine receptors (muscarinic) in GtoPdb v.2021.2

2021

Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [50]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in the human body and are therefore attractive targets for many disorders. Functionally, M1, M3, and M5 mAChRs preferentially couple to Gq/11 proteins, whilst M2 and M4 mAChRs predominantly couple to Gi/o proteins. Both agonists and antagonists of mAChRs are clinically approved drugs, including pilocarpine for the treatment of elevated intra-ocular pressure and glaucoma, and atropine for the treatment of bradycardia and poisoning by muscarinic age…

BradycardiaAtropineChemistryPilocarpineMuscarinic acetylcholine receptormedicinemedicine.symptomPharmacologyMuscarinic AgentsAcetylcholineEndogenous agonistmedicine.drugAcetylcholine receptorIUPHAR/BPS Guide to Pharmacology CITE
researchProduct

Acetylcholine receptors (muscarinic) in GtoPdb v.2021.3

2021

Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [50]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in the human body and are therefore attractive targets for many disorders. Functionally, M1, M3, and M5 mAChRs preferentially couple to Gq/11 proteins, whilst M2 and M4 mAChRs predominantly couple to Gi/o proteins. Both agonists and antagonists of mAChRs are clinically approved drugs, including pilocarpine for the treatment of elevated intra-ocular pressure and glaucoma, and atropine for the treatment of bradycardia and poisoning by muscarinic age…

BradycardiaAtropinePilocarpineChemistryMuscarinic acetylcholine receptormedicinePharmacologymedicine.symptomMuscarinic AgentsEndogenous agonistAcetylcholinemedicine.drugAcetylcholine receptorIUPHAR/BPS Guide to Pharmacology CITE
researchProduct

The conservation of the environment in Ecuador's constitution

2017

The 2008 Ecuadorian Constitution is often presented as building on the local traditions of indigenous peoples in order to propose a non-anthropocentric approach to the conservation of the environment, based on the concept of buen vivir. After providing a short introduction on anthropocentric and non-anthropo-centric approaches to the environment, with attention to indigenous worldviews, this article attempts to: analyse the concept of buen vivir, appearing to have unclear boundaries; understand whether or not it is a concept derived from indigenous worldviews; and explore the innovative non-anthropocentric feature of the recognition of rights to the environment. Finally, the article uses th…

Buen vivir Constitution Ecuador Environmental rights Indigenous peoplesSettore SPS/01 - Filosofia PoliticaK
researchProduct