6533b7d1fe1ef96bd125d8d6

RESEARCH PRODUCT

An overview of doping in sports

Vladimir E. Martínez-belloMari Carmen Gomez-cabreraHelios Pareja-galeanoFabian Sanchis-gomarThomas BriocheThomas Brioche

subject

Bioquímicaprotein synthesis[SDV]Life Sciences [q-bio]anabolic androgenic steroidsPharmacologyProtein chemistry01 natural sciencesDopaje03 medical and health sciencesCondensed Matter::Materials SciencePhysics::Popular PhysicsBlood dopingerythropoiesis-stimulating agentsGene dopinghuman urineCondensed Matter::SuperconductivityToxicologíaComputer Science::Multimediaaromatase inhibition030304 developmental biology0303 health sciencesAromatase inhibitionbody compositionChemistryexogenous growth hormone010401 analytical chemistryMedicina deportivaskeletal muscle massAnabolic-Androgenic SteroidsSkeletal muscle massGenética3. Good health0104 chemical sciencesautologous blood transfusionsCondensed Matter::Strongly Correlated Electronshuman activitiesClinical psychology

description

The history of doping field can be outlined in three major stages: (1) early stage in which drug abuse took place during sports performance and competition and gas chromatography was used for its detection; (2) approximately in the 1970s when androgenic anabolic steroids were introduced; (3) In the recent era when the fields of biochemistry, physiology, toxicology, genomics, genetics, immunology, and molecular biology were integrated and applied routinely. Advanced omics technology and gene doping age may be applied in near future. This review will discuss commonly abused materials, both their adverse and harmful effects, and the alleged benefits in conjunction with the current standards in doping. Five prime areas should be targeted: (1) substances misused in strength sports; (2) metabolic modulators/hormones; (3) blood doping in aerobic sports; (4) structurally diverse masking agents; and (5) gene doping. Sin financiación No data 2019 UEM

10.1016/b978-0-12-813922-6.00016-3https://hal.archives-ouvertes.fr/hal-02269500