Search results for "Gold"
showing 10 items of 1320 documents
Gold Nanoparticles Supported on Nanoparticulate Ceria as a Powerful Agent against Intracellular Oxidative Stress
2012
Ceria-supported gold nanoparticles are prepared exhibiting peroxidase activity and acting as radical traps. Au/CeO2 shows a remarkable biocompatibility as demonstrated by measuring cellular viability, proliferation, and lack of apoptosis for two human cell lines (Hep3B and HeLa). The antioxidant activity of Au/CeO2 against reactive oxygen species (ROS) is demonstrated by studying the cellular behavior of Hep3B and HeLa in a model of cellular oxidative stress. It is determined that Au/CeO2 exhibits higher antioxidant activity than glutathione, the main cytosolic antioxidant compound, and its CeO2 carrier. Overall the result presented here shows the potential of implementing well-established …
Detoxifying antitumoral drugs via nanoconjugation: the case of gold nanoparticles and cisplatin
2021
Nanoparticles (NPs) have emerged as a potential tool to improve cancer treatment. Among the proposed uses in imaging and therapy, their use as a drug delivery scaffold has been extensively highlighted. However, there are still some controversial points which need a deeper understanding before clinical application can occur. Here the use of gold nanoparticles (AuNPs) to detoxify the antitumoral agent cisplatin, linked to a nanoparticle via a pH-sensitive coordination bond for endosomal release, is presented. The NP conjugate design has important effects on pharmacokinetics, conjugate evolution and biodistribution and results in an absence of observed toxicity. Besides, AuNPs present unique o…
First-principles simulations of hydrogen peroxide formation catalyzed by small neutral gold clusters.
2009
Energetics and dynamical pathways for hydrogen peroxide formation from H(2) and O(2) bound to neutral gold dimers and tetramers have been investigated by applying several strategies: T = 0 K geometry optimizations, constrained Car-Parrinello molecular dynamics simulations at T = 300 K and metadynamics at T = 300 K. The competing reaction channels for water and hydrogen peroxide formation have been found and characterized. In each case, the reaction barriers for Au cluster catalyzed proton transfer are less than 1 eV. Water formation is a competitive reaction channel, and the relative weight of H(2)O and H(2)O(2) products may depend on the chosen Au cluster size. Dynamic simulations demonstr…
Scrutiny of annexin A1 mediated membrane-membrane interaction by means of a thickness shear mode resonator and computer simulations.
2004
The dissipational quartz crystal microbalance (D-QCM) technology was applied to monitor the adsorption of vesicles to membrane-bound annexin A1 by simultaneously reading out the shifts in resonance frequency and dissipation. Solid-supported membranes (SSMs) composed of a chemisorbed octanethiol monolayer and a physisorbed 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoserine monolayer were immobilized on the gold electrode of a 5 MHz quartz plate. Adsorption and desorption of annexin A1 to the SSM was followed by means of the QCM technique. After nonbound annexin A1 was removed from solution, the second membrane binding was monitored by the D-QCM t…
Micro/nanostructured thin films : synthesis by ALD of composites associating TiO2 inverse opals and gold nanoparticles for photocatalysis applications
2021
The aim of this work was to improve the photocatalytic properties of titanium dioxide (TiO2) thin films, a semiconductor that is widely used for photocatalysis applications, particularly for the treatment of polluted water. For this purpose, two complementary approaches were studied: increasing the surface area available for photocalatytic reactions and coupling between TiO2 and gold nanoparticles.. For the first approach, TiO2 thin films with different morphological structures were fabricated by Atomic Layer Deposition: dense and porous flat films, and inverse opals films.In order to evaluate photocatalytic activity of the different films, the degradation of methylene blue in aqueous solut…
Formation of a micropatterned titania photocatalyst by microcontact printed silicatein on gold surfaces
2012
The enzyme silicatein has been bioengineered to carry a thiol-bearing Au-affinity tag (Cys-tag) for direct immobilization on gold carriers in shortest time without the need for prior surface functionalization. Through microcontact printing, defined silicatein micropatterns were created on gold surfaces, facilitating the subsequent enzymatically controlled synthesis of photocatalytically active TiO(2).
CCDC 216063: Experimental Crystal Structure Determination
2005
Related Article: I.Rojo, F.Teixidor, C.Vinas, R.Kivekas, R.Sillanpaa|2004|Chem.-Eur.J.|10|5376|doi:10.1002/chem.200400361
Species differences, influence of dose and application on biotransformation of phenol in fish.
1983
1. The metabolism of phenol in goldfish (Carassius auratus), rainbow trout (Salmo gairdneri) and goldenorfe ide (Leuciscus ideus melanotus) was compared. All three species produced phenyl sulphate, quinol sulphate and phenyl glucuronide. 2. The dose dependence of metabolism of phenol in goldfish was investigated. When the concn. of phenol was increased from 0.2 to 2 mg/l medium, that glucuronylated increased from 7 to 16% and that sulphated decreased from 63 to 47%. 3. The influence of mode of exposure on metabolism of phenol in goldfish was examined. Dietary exposure and uptake from medium was compared with i.p. injection. There was less metabolism in the order: dietary exposure greater th…
Sinǝзi naj Gara
1932
Stāsts nanaju (goldu) valodas apguvei.
Nanaj hǝsǝwǝni taceoceori daŋsa boŋgodu taceocemi tǝpciuuri skoladu: grammatika tǝrǝk niruuri: II pasi: elacean, dujǝciǝn klass
1935
Nanaju (goldu) valodas mācību grāmata 3. un 4. klasei.