Search results for "Gout"
showing 10 items of 44 documents
2001 : l'odyssée des sens
2001
International audience
The influence of olfactory sensitivity on food preferences in very young children : the case of goat cheese and cauliflower
2001
National audience
Comparison of the trigeminal effects of several mustards and spices
2001
National audience
Podagras pacientu līdzestība medikamentu lietošanā un to ietekmējošie faktori
2019
Podagra ir viens no iekaisīgā artrīta veidiem. Tai raksturīgi vielu maiņas traucējumi, kas saistīti ar urīnskābes sāļu uzkrāšanos un izgulsnēšanos locītavās un ķermeņa audos. Tie rodas purīnu un urīnskābes vielu maiņas traucējumu rezultātā. Podagra ir nopietna slimība, kuras nepareiza aprūpe palaiž secīgi citu slimību attīstību un visu slimību kopums padara vēl sarežģītāku aprūpi māsām. Podagras terapijai pieejamie medikamenti nav iekļauti Valsts kompensējamo zāļu sarakstā. Latvijas aptiekās tie ir izsniedzami tikai pret parasto recepti. Tika pieņemts lēmums dziļāk izpētīt šo jautājumu. Tika izvirzīts darba mērķis un saņemta atļauja pētījumam no ētikas komisijas. Pētījumā ietvaros tika apko…
Saisies gastronomiques ou La nostalgie au futur
2019
Cet article porte sur deux questions : sur la transposition de l’opposition conceptuelle plastique / figuratif de la dimension visuelle à celle du goût, et sur la passion qu’on appelle la nostalgie, considérée dans ses rapports avec les processus de figurativisation de l’expérience gustative et son évaluation par la critique gastronomique. Pour en traiter, nous nous appuyons notamment sur la reprise cinématographique du discours gastronomique proposée par un film d’animation intitulé Ratatouille, et en particulier sur la saisie esthétique que ce film met en scène. Ainsi, la question sémiotique de la médiation visuelle (et, en général, figurative) va nous intéresser non seulement en elle-mêm…
Anti-gout drugs as potential therapy for atrial fibrillation.
2014
Atrial fibrillation (AF) is an important cardiovascular disease in theelderly [1]. Noticeably, it has been increasingly demonstrated thatserum uric acid (UA) is associated with AF [2–9]. In a recent meta-analysis performed by Tamariz and coworkers, the authors concludedthat high levels of UA and AF are clearly associated [10]. Interestingly,serum UA has been linked to AF in obstructive sleep apnea patients[11], whereas it has been also associated with thromboembolic risk inpatients with nonvalvular AF [12].The treatment of gout, a metabolic disorder caused by chronic hyper-uricemia, is based on administration of colchicine, xanthine oxidase (XO)competitive inhibitors such as allopurinol, and…
Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease
2020
During the last century, there has been an increasing prevalence of hyperuricaemia noted in many populations. While uric acid is usually discussed in the context of gout, hyperuricaemia is also associated with hypertension, chronic kidney disease, hypertriglyceridaemia, obesity, atherosclerotic heart disease, metabolic syndrome, and type 2 diabetes. Here we review the connection between hyperuricaemia and cardiovascular, kidney and metabolic diseases. Contrary to the popular view that uric acid is an inert metabolite of purine metabolism, recent studies suggest serum uric acid may have a variety of pro-inflammatory, pro-oxidative and vasoconstrictive actions that may contribute to cardiomet…
Hyperuricemia and non-dipping blood pressure
2013
Dear editor The strong association between the metabolic derangements that characterize the metabolic syndrome with arterial hypertension is very well-known, as it is the common finding of hyperuricemia in the patients with the metabolic syndrome. Besides, hyperuricemia has been found to be associated with cardiovascular, renal, and metabolic diseases; including not only gout but also type 2 diabetes mellitus, although its role as a risk factor is still debated.1 We were not aware of previous studies describing an association between uric acid levels and the non-dipping 24-hour blood pressure (BP) pattern, and for that reason we were intrigued by Tutal et al’s article, regarding hypertensiv…
Agouti-related peptide-expressing neurons are mandatory for feeding.
2005
Multiple hormones controlling energy homeostasis regulate the expression of neuropeptide Y (NPY) and agouti-related peptide (AgRP) in the arcuate nucleus of the hypothalamus. Nevertheless, inactivation of the genes encoding NPY and/or AgRP has no impact on food intake in mice. Here we demonstrate that induced selective ablation of AgRP-expressing neurons in adult mice results in acute reduction of feeding, demonstrating direct evidence for a critical role of these neurons in the regulation of energy homeostasis.
SAT0571 OPTICAL SPECTRAL TRANSMISSION TO ASSESS THERAPY RESPONSE IN PATIENTS WITH ARTHRITIS: A COMPARATIVE STUDY WITH CLINICAL, LABORATORY AND ULTRAS…
2020
Background:Valid assessment of disease activity leads to outcome improvement in patients with rheumatoid arthritis (RA) (1). Optical spectral transmission (OST) is a modern diagnostic tool able to assess the blood-specific absorption of light transmitted through a tissue, promising quantification of inflammation in the finger and wrist joints of RA patients (commercial device: HandScan - Hemics, The Netherlands) (2).Objectives:To our knowledge, there are no data regarding the diagnostic value of OST in the evaluation of inflammatory activity changes during arthitis follow up.Thus, aims of this study were to examine the ability of OST to detect response to anti-inflammatory therapy in patien…