Search results for "HILIC"
showing 10 items of 745 documents
Meibomian glands structure in daily disposable soft contact lens wearers: a one‐year follow‐up study
2020
Purpose To assess the impact of daily disposable soft contact lenses on meibomian gland morphology over a period of 12 months. Methods Forty-one subjects (33 experienced and 8 neophytes) were fitted with either silicone-hydrogel or hydrogel daily contact lenses. The study protocol included four visits: baseline, day-2 for contact lens fit and follow-up measurements, as well as after 6 and 12 months of lens wear. Non-contact infrared meibography images were acquired with Keratograph 5M topographer (www.oculus.de) and analysed with an automated method, which objectively estimates the area of gland atrophy, gland length and width, number of glands and gland irregularity. Protocol at follow-up …
Ocular surface assessment in soft contact lens wearers; the contribution of tear osmolarity among other tests.
2014
: Purpose: To determine whether tear osmolarity contributes to the assessment of the ocular surface in soft contact lens (CL) wearers. Methods: Prospective, case–control series in 44 CL wearers (28 tolerant and 16 intolerant) and 34 healthy subjects. Every patient underwent a thorough ophthalmic examination with a tear osmolarity test (TearLab System), conjunctival impression cytology and meibomian lipid sampling. Symptoms, break-up time (BUT), tear osmolarity, conjunctival expression of HLA-DR and meibomian fatty acid composition were evaluated. Results: Tear osmolarity did not differ between controls and CL wearers (p = 0.23). Flow cytometry results expressed in antibody-binding capaci…
Assessment of induced corneal hypoxia in diabetic patients
2002
Comparative Study Address correspondence and reprint requests to Dr. C. Creuzot-Garcher, Service d'Ophtalmologie, CHU, Hopital Général, 3 Rue du Faubourg Raines, BP 1519, 21033 Dijon, France. E-mail: Catherine.creuzot-garcher@chu-dijon.fr; To assess the control of corneal hydration in patients with diabetes during a contact lens-induced hypoxia. Corneal stress was induced in 15 patients with diabetes and 23 healthy patients by having them wear contact lenses for 2 hours. Pachymetries were measured and corneal parameters (percentage recovery per hour [PRPH], time for deswelling [T99%] and induced swelling [IS]) were calculated. In the mean time, tears were collected to assess the activity of…
Prevention of haemophilic arthropathy during childhood. May common orthopaedic management be extrapolated from patients without inhibitors to patient…
2008
We recommend prophylaxis in haemophilic children with an inhibitor as a way of preventing the musculoskeletal impairment that is likely to affect them. This approach has been used for children without inhibitors with excellent results. If prophylaxis is not feasible, we suggest that intensive on-demand treatment should be given. Two agents, recombinant activated FVII (rFVIIa) and activated prothrombin complex concentrates (aPCC), are currently used to control haemostasis either for prophylaxis or intensive on-demand treatment. As it is recombinant, rFVIIa would seem more appropriate to be employed in children. aPCC could be used in adults, or in the event of an unsatisfactory response to rF…
Effects of performing dual tasks on postural sway and postural control complexity in people with haemophilic arthropathy
2019
Introduction People with haemophilic arthropathy (PWHA) have impairments in postural control. However, little is known about the effects of demanding conditions, including the unipedal stance and dual tasks, on postural control in PWHA. Aim Determine the effects of performing dual tasks while in the one-leg stance on postural sway and postural control complexity in PWHA vs. healthy active (HAG) and non-active (HNAG) groups of individuals. Methods Fifteen PWHA and 34 healthy subjects (18 active and 16 non-active) were recruited. Vertical (V), mediolateral (ML) and anteroposterior (AP) centre of mass signals were acquired using a 3-axis accelerometer placed at the L3/L4 vertebrae of subjects …
Post-LASIK Visual Quality With a Corneoscleral Contact Lens to Treat Irregular Corneas.
2015
To evaluate the visual quality results of fitting a corneoscleral contact lens with multiaspheric geometry design (MAGD CScL) in subjects with irregular corneas after laser-assisted in situ keratomileusis (LASIK) surgery.From a database of patients evaluated for scleral contact lenses, we identified those with irregular corneas and visual problems after they underwent LASIK surgery for correcting myopia. They manifested unsatisfactory visual quality with their current contact lenses or glasses. Therefore, a MAGD CScL was fitted and monitored according to standardized fitting methodology. A diagnostic trial set was used in the fitting process. Visual acuity (VA), subjective visual quality (S…
Assessment of Kinect V2 for elbow range of motion estimation in people with haemophilia using an angle correction model
2018
Introduction The joint range of motion (ROM) is an important clinical parameter used to assess the loss of functionality resulting from joint bleedings in people with haemophilia. These episodes require a close follow-up and, to decrease patients' hospital dependence, telemedicine tools are needed. Therefore, this study is aimed to analyse the validity of the Microsoft Kinect V2 sensor with corrected angle measurement to be used in the monitoring of elbow ROM in people with haemophilia. Methods A convenience sample of 10 healthy controls (CG) and 10 patients with haemophilia with elbow arthropathy (HG) participated in this study. Full ROM of elbow joints was measured in the frontal view wit…
Effect of 3rd-order aberrations on human vision
2007
To investigate the effect of 3rd-order aberrations on human vision.Grupo de Ciencias de la Visión, University of Murcia, Murcia, Spain.The 3rd-order aberrations coma and trefoil were induced with purpose-designed soft contact lenses, 3 inducing coma (low [0.05 microm], medium [0.13 microm], high [1.03 microm]) and 3 inducing trefoil (low [0.07 microm], medium [0.17 microm], high [0.96 microm]). Monocular high-contrast (HCVA) and low-contrast (LCVA) visual acuities and contrast sensitivity were measured in 11 subjects wearing contact lenses with a 5.0 mm artificial pupil.The reduction in HCVA and LCVA was statistically significant only for the highest coma and trefoil values (P.0001). For co…
Tear film stability over a myopia control contact lens compared to a monofocal design
2021
Background: To compare the short-term effect of two contact lenses on pre-lens tear film stability and comfort: dual-focus contact lens (MiSight) and a monofocal contact lens (Proclear 1-day).Methods: This randomised, double-masked, crossover study was performed in twenty-eight healthy, myopic volunteers aged between 18 and 32 years (23.5 +/- 4.1 years). Only one randomly chosen eye was assessed. Distance vision and refraction were evaluated at baseline. Each contact lens type (monofocal and dual-focus) was randomly fitted, always in both eyes. A visual analogue scale between 0 and 10 was used to assess general comfort, physical comfort, and visual comfort. Tear Film Surface Quality (TFSQ) …
Results of an orthopaedic survey in young patients with severe haemophilia in Spain
2002
Summary. This paper outlines the results obtained in a cross-sectional study of a group of young patients with severe haemophilia A and B. The primary aim of the study was to ascertain the level of orthopaedic complications in the group, the effects that these complications have on quality of life, and the medical resources used on these patients. The secondary aim was to relate their current orthopaedic state to the type of treatment received before the study. The study was carried out in 11 hospitals in Spain, where 70 severe haemophilia patients (factor VIII [FVIII] < 2%), with an average age of 21.6 and a median age of 22, and no inhibitors, were monitored. The percentage of patients s…