Search results for "HP"
showing 10 items of 1505 documents
Human Leukocyte Antigen Typing Using High-Throughput DNA and RNA Sequencing and Application for Cell Line Identification
2019
Multicriteria methods in evaluation of city logistics projects
2017
Multi-criteria decision making (MCDM) methods are chosen among alternatives in order to attain specific objectives. In this research, the purpose of methodology is to provide decision methods for project managers in city logistics. The methodology is combined into two methods consisting of Analytic Hierarchy Process (AHP) and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS). As the result, the criteria for selection are determined by expert opinions, and then assign the weight of criteria by AHP. Finally, TOPSIS method is used to evaluate alternatives which are found prioritized by weight for project , namely project C equal 0.537 , project A equal 0.438 , project B e…
Multicriteria decision making taxonomy of code recommendation system challenges: a fuzzy-AHP analysis
2022
AbstractThe recommendation systems plays an important role in today’s life as it assist in reliable selection of common utilities. The code recommendation system is being used by the code databases (GitHub, source frog etc.) aiming to recommend the more appropriate code to the users. There are several factors that could negatively impact the performance of code recommendation systems (CRS). This study aims to empirically explore the challenges that could have critical impact on the performance of the CRS. Using systematic literature review and questionnaire survey approaches, 19 challenges were identified. Secondly, the investigated challenges were further prioritized using fuzzy-AHP analys…
DIAGSOL : Développement d’un outil microbien pour évaluer l’exposition des sols agricoles aux herbicides β-tricétones
2018
International audience; En 2011, en France, plus de 2 millions d’hectares de champs de maïs ont été traités avec desherbicides β-tricétones. Qualifiés de « respectueux de l’environnement » en raison d’une efficacité àfaible dose, de récentes études ont démontré un effet transitoire des β-tricétones sur la diversitébactérienne des sols (Romdhane et al., 2016). L’utilisation récurrente des β-tricétones pourrait, àterme, perturber la diversité bactérienne et les fonctions écosystémiques des sols qu’elle soutient.Il est essentiel d’évaluer l’exposition des microorganismes des sols aux β-tricétones.L’enzyme 4-hydroxyphénylpyruvate dioxygénase (4-HPPD), cible de ces herbicides chez les plantesadv…
DELPHI-AHP AS TOOL TO ASSESS TOURISM DESTINATION COMPETITIVENESS: A CASE STUDY OF NAUTICAL TOURISM IN SARDINIA
2014
Increased conformational rigidity of humic substances by oxidative biomimetic catalysis
2005
A synthetic water-soluble meso-tetra(2,6-dichloro-3-sulfonatophenyl)porphyrinate of iron(III) chloride, Fe(TDCPPS)Cl, was employed as a biomimetic catalyst in the oxidative coupling of terrestrial humic materials. High-performance size-exclusion chromatography (HPSEC), solid-state nuclear magnetic resonance (CPMAS-(13)C NMR), electron paramagnetic resonance (EPR), and diffuse reflectance infrared spectroscopy (DRIFT) were used to follow conformational and structural changes brought about in different humic materials by the oxidative coupling. Increase in apparent weight-average molecular weight (Mw(a)) occurred invariably for all humic substances with the oxidative polymerization catalyzed …
Current development of CFTR potentiators in the last decade
2020
Cystic fibrosis (CF) is a genetic disorder produced by the loss of function of CFTR, a main chloride channel involved in transepithelial salt and water transport. CFTR function can be rescued by small molecules called "potentiators" which increase gating activity of CFTR on epithelial surfaces. High throughput screening (HTS) assays allowed the identification of new chemical entities endowed with potentiator properties, further improved through medicinal chemistry optimization. In this review, the most relevant classes of CFTR potentiators developed in the last decade were explored, focusing on structure-activity relationships (SAR) of the different chemical entities, as a useful tool for t…
ANKRD26-RET - A novel gene fusion involving RET in papillary thyroid carcinoma
2018
Abstract Background Rearrangements of RET are drivers of oncogenesis, traceable in different cancer types as papillary thyroid carcinoma (PTC), non-small cell lung cancer, colorectal or breast cancer. Anchored multiplex PCR based next-generation sequencing (NGS) can detect RET rearrangements involving previously unknown partner genes. Methods A sample of PTC underwent NGS, following detection of RET rearrangement by fluorescence in situ hybridization. Expression analysis of ANKRD26 and RET was performed for the tumor harboring ANKRD26-RET, for corresponding normal thyroid tissue and PTC tumors with representative genetic alterations (BRAFV600E, CCDC6-RET), complemented by a comparative sear…
Presiones antropogénicas en el Parque Natural de L’Albufera: Contaminación debida a fármacos y productos para el cuidado personal
2021
La contaminación medio ambiental, debida a la actividad antrópica, ha crecido de forma exponencial en el último siglo. Por esta razón la tesis se ha centrado en una clase de contaminantes, fiel reflejo de esta presión, los fármacos y productos para el cuidado personal (PPCPs). El trabajo realizado incluye la optimización de métodos analíticos para detectar estos compuestos y la aplicación de estos a muestras medioambientales, para evaluar el estado de contaminación de una importante Reserva Natural. En primer lugar, se realizó una revisión bibliográfica que describe la importancia de cada paso en la preparación de la muestra para optimizar la determinación de estos contaminantes en ecosiste…
The effective cross section for double parton scattering within a holographic AdS/QCD approach
2017
A first attempt to apply the AdS/QCD framework for a bottom-up approach to the evaluation of the effective cross section for double parton scattering in proton-proton collisions is presented. The main goal is the analytic evaluation of the dependence of the effective cross section on the longitudinal momenta of the involved partons, obtained within the holographic Soft-Wall model. If measured in high-energy processes at hadron colliders, this momentum dependence could open a new window on 2-parton correlations in a proton.