Search results for "Halloysite"

showing 10 items of 185 documents

Chemical and biological evaluation of cross-linked halloysite-curcumin derivatives

2020

Abstract Well designed and safe nano drug carrier systems are an important tool in biomedical applications. The combination of two or more drugs has been used in medicine both to enhance the therapeutic effect and to decrease the side effects of drugs. Biocompatible halloysite nanotubes, that possess two different surfaces, are a suitable nanomaterial for a simultaneous carrier and release of two drugs that can exert a synergistic effect against cancer cells. In this study, three curcumin derivatives and doxorubicin were loaded by supramolecular and covalent linkage at the lumen and external surface of the halloysite nanotubes. The obtained multifunctional systems were characterized by seve…

Drugmedia_common.quotation_subjectNanoparticle020101 civil engineering02 engineering and technologyengineering.materialHalloysite0201 civil engineeringchemistry.chemical_compoundGeochemistry and PetrologymedicineDoxorubicinCytotoxicitymedia_commonSettore CHIM/02 - Chimica FisicaHalloysite nanotubes Curcumin derivatives Dual drug delivery Antiproliferative activity Breast cancer cell lines and acute myeloid leukemia cell linesChemistryGeologySettore CHIM/06 - Chimica Organica021001 nanoscience & nanotechnology3. Good healthCancer cellBiophysicsengineeringCurcuminSettore BIO/14 - Farmacologia0210 nano-technologyDrug carriermedicine.drug
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Current Status of Nanoclay Phytotoxicity

2018

The use of nanotechnology in several fields has created a great interest and its rapid development with application in material science, nanomedicine, medical diagnosis, computer chips, catalysis and so on. The use of nanomaterials represents various advantages, including size, highly active surfaces, unique physico-chemical properties, and in some cases a controlled release of chemicals. In this context phyto-nanotechnology is growing and has promising application in agricultural aspects, such as use of soil remediation, antioxidants, adsorbents, nano-sensor for detection of soil quality, delivery of fertilizers and many others. Plants are very important components of the terrestrial eco-s…

Engineeringbusiness.industryNanotechnologySettore CHIM/06 - Chimica Organica02 engineering and technologyClay minerals halloysite nanotubes phytotoxicity010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesNanomedicinePhytotoxicityCurrent (fluid)0210 nano-technologybusinessSettore CHIM/02 - Chimica Fisica
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Assisted phytostabilization of soil from a former military area with mineral amendments.

2019

Abstract Due to the presence of toxic pollutants, soils in former military areas need remedial actions with environmentally friendly methods. Greenhouse experiments were conducted to investigate the aided phytostabilization of multi-heavy metals (HMs), i.e. Cd, Cr, Cu, Ni, Pb, Zn, in post-military soil by Festuca rubra and three mineral amendments (diatomite, dolomite and halloysite). The amendments were applied at 0 and 3.0% to each pot filled with 5 kg of polluted soil. After seven weeks of the phytostabilization, selected soil properties, biomass yield of F. rubra and immobilization of HMs by their accumulation in plant and redistribution among individual fractions in soil were determine…

FestucaHealth Toxicology and MutagenesisDolomite0211 other engineering and technologies02 engineering and technology010501 environmental sciencesengineering.material01 natural sciencesHalloysitePlant RootsCalcium CarbonateSoilMetals HeavyMilitary FacilitiesEcotoxicologySoil PollutantsMagnesiumBiomassEnvironmental Restoration and Remediation0105 earth and related environmental sciencesPollutant021110 strategic defence & security studiesbiologyChemistryPublic Health Environmental and Occupational HealthGeneral Medicinebiology.organism_classificationPollutionSoil conditionerRemedial actionBiodegradation EnvironmentalEnvironmental chemistrySoil waterengineeringClayFestuca rubraEcotoxicology and environmental safety
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Halloysite nanotubes: a green resource for materials and life sciences

2020

Clay minerals are considered one of the materials of the 20th century for their peculiar physico-chemical features. Among them, halloysite nanotubes (HNTs) are an emerging nanomaterial with a particular tubular structure that makes them a low cost and valuable alternative to the most common carbon nanotubes. Due to their tubular morphology, HNTs are employed in several fields acting as nanocontainers for different compounds for applications in drug carrier and delivery fields, catalysis, and as filler for polymeric matrices. The modification of HNTs’ surfaces allows to the synthesis of different nanoarchitectures that can improve the mechanical and thermal performance of polymer as well as …

Filler (packaging)Materials scienceSupramolecular chemistryNanotechnologyCarbon nanotubeengineering.material01 natural sciencesHalloysiteNanomaterialslaw.invention03 medical and health scienceslawHalloysite nanotubes Covalent modification Supramolecular interaction Drug carrier and delivery Catalysis0103 physical sciences010303 astronomy & astrophysicsGeneral Environmental ScienceSettore CHIM/02 - Chimica Fisicachemistry.chemical_classification0303 health sciencesPolymerSettore CHIM/06 - Chimica Organica030301 anatomy & morphologychemistryengineeringGeneral Earth and Planetary SciencesSurface modificationGeneral Agricultural and Biological SciencesDrug carrier
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Magnetic coiffure: Engineering of human hair surfaces with polyelectrolyte-stabilised magnetite nanoparticles

2022

Here we report a spontaneous electrostatic coating of human hair with aqueous Fe3O4 colloids capable to tailor magnetic properties to hair, orienting and even moving them under the influence of the external magnetic field. Magnetite particles were modified by cationic and anionic polyelectrolytes and then successfully deposited in dense arrays, starting from cuticle gaps and spreading further over a major hair surface. These biocompatible and biodegradable magnetic nanoparticles may serve as carriers for drug loading and delivery for topical pharmaceutical treatments. The deposition process was imaged in real-time using dark-field microscopy. The hair specimens were further studied using a …

General Chemical EngineeringPolyelectrolytes AFM Halloysite HairEnvironmental ChemistryGeneral ChemistryIndustrial and Manufacturing EngineeringSettore CHIM/02 - Chimica Fisica
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Photostability assessment of natural pyrethrins using halloysite nanotube carrier system

2022

Natural pyrethrins are one of the most used pesticides and insect repellents employed for domestic or agronomic use. However, they are highly hydrophobic and suffer from insolubility in water media and ready decomposition by photochemical, and oxidative actions. These aspects hamper their long-term storage and applicability. Herein, we report the synthesis and characterization of a nanomaterial based on the loading of pyrethrum extract (PE) into natural, low-cost, and eco-compatible halloysite nanotubes (Hal). The Hal/PE nanomaterial was thoroughly characterized, and the morphology was imaged by TEM and SEM investigations. Release experiments showed a slow release of pyrethrins from the car…

Geochemistry and PetrologyGeologySettore CHIM/06 - Chimica OrganicaPyrethrins Halloysite Photoprotection Nanopesticides
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Direct chemical grafted curcumin on halloysite nanotubes as dual-responsive prodrug for pharmacological applications

2016

Covalently functionalized halloysite nanotubes (HNTs) were successfully employed as dual-responsive nanocarriers for curcumin (Cur). Particularly, we synthesized HNT-Cur prodrug with a controlled curcumin release on dependence of both intracellular glutathione (GSH) and pH conditions. In order to obtain HNT-Cur produgs, halloysite was firstly functionalized with cysteamine through disulphide linkage. Afterwards, curcumin molecules were chemically conjugated to the amino end groups of halloysite via Schiff's base formation. The successful functionalization of halloysite was proved by thermogravimetric analysis, FT-IR spectroscopy, dynamic light scattering and scanning electron microscopy. Ex…

Halloysite nanotubeAntiproliferative activity02 engineering and technology01 natural scienceshalloysite nanotubes covalent functionalization curcumin prodrugchemistry.chemical_compoundColloid and Surface ChemistryOrganic chemistryProdrugsProdrugSettore CHIM/02 - Chimica FisicaDrug CarriersNanotubesChemistryAntioxidant propertieFree Radical ScavengersSurfaces and InterfacesGeneral MedicineProdrug021001 nanoscience & nanotechnologyDrug deliveryAluminum Silicates0210 nano-technologyDrug carrierOxidation-ReductionBiotechnologyCurcuminCell SurvivalAntineoplastic AgentsHalloysite nanotubes Curcumin Prodrug Antiproliferative activity Antioxidant propertiesengineering.materialConjugated system010402 general chemistryHalloysiteCell Line TumorHumansPhysical and Theoretical ChemistryCell ProliferationSettore CHIM/06 - Chimica OrganicaCombinatorial chemistry0104 chemical sciencesKineticsMicroscopy Electron ScanningengineeringCurcuminSettore BIO/14 - FarmacologiaClayPharmaceuticsNanocarriers
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1,2,3-Oligotriazoles modified halloysite nanotubes as potential active biological species: synthesis and characterization

2022

In the last years, the development of nano-formulations for cancer treatment represents one of the major challenges of the scientific research. The prodrug strategy, that combines chemotherapeutic agents with nanocarriers such as halloysite nanotubes (HNTs), is a promising strategy both to improve the biological activity of the drug molecules and to reduce the side effects of drugs. Herein we report the synthesis and characterization of a HNTs prodrug based on 1,2,3-triazole units covalently linked to HNTs external surface, bearing different positively charged moieties, which could present interesting pharmacological activities.

Halloysite nanotubes123-oligotriazolecovalent modificationOrganic ChemistryHuisgen reactionSettore CHIM/06 - Chimica OrganicaHNTs-prodrugSettore CHIM/02 - Chimica FisicaArkivoc
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Halloysite Nanotubes: Smart Nanomaterials in Catalysis

2022

The use of clay minerals as catalyst is renowned since ancient times. Among the different clays used for catalytic purposes, halloysite nanotubes (HNTs) represent valuable resources for industrial applications. This special tubular clay possesses high stability and biocompatibility, resistance against organic solvents, and most importantly be available in large amounts at a low cost. Therefore, HNTs can be efficiently used as catalysts themselves or supports for metal nanoparticles in several catalytic processes. This review reports a comprehensive overview of the relevant advances in the use of halloysite in catalysis, focusing the attention on the last five years.

Halloysite nanotubesCovalent approachMetal nanoparticlesSettore CHIM/06 - Chimica OrganicaPhysical and Theoretical ChemistryCatalyst supportCatalysisCatalysts
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Orientation of charged clay nanotubes in evaporating droplet meniscus.

2015

© 2014 Elsevier Inc. During drying, an aqueous suspension of strongly charged halloysite clay nanotubes concentrates at the edge of the droplet ("coffee-ring" effect) which provides alignment of the tubes along the liquid-substrate contact line. First, the surface charge of the nanotubes was enhanced by polyanion adsorption inside of the lumen to compensate for the internal positive charges. This increased the magnitude of the ξ-potential of the tubes from -36 to -81mV and stabilized the colloids. Then, colloidal halloysite was dropped onto the substrate, dried at 65°C and after a concentration of ~0.05mgmL-1 was reached, the alignment of nanotubes occurred starting from the droplet edges. …

Halloysite nanotubes;Alignment;Droplet evaporation;Coffee ring;Liquid crystalMaterials scienceHalloysite nanotubeCoffee ring effectNanotechnologyengineering.materialHalloysiteBiomaterialsDroplet evaporationColloidColloid and Surface ChemistryAdsorptionLiquid crystalSurface chargeAlignmentMicrochannelNanotubesHalloysite nanotubesOsmolar ConcentrationHydrogen-Ion ConcentrationSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsChemical engineeringLiquid crystalengineeringCoffee ringMicroscopy Electron ScanningClayNanorodAluminum SilicatesCrystallizationJournal of colloid and interface science
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