Search results for "Head and Neck"

Fehlerquellen der Navigation in der lateralen Sch�delbasischirurgie

2003

Die Identifikation moglicher Storfaktoren navigationsunterstutzter Eingriffe an der lateralen Schadelbasis ermoglichen dem Anwender die Vermeidung und Behebung dieser Fehler. Anhand unserer Erfahrungen von 85 navigationsunterstutzten Eingriffen im Bereich der lateralen Schadelbasis werden Fehler der Hard- und Software, der Bildgebung und des -transfers, der Patientenregistrierung, durch den Anwender und solche strategischer Art analysiert. Bei optischen CAS-Systemen fuhrt eine Blockade des Sichtfelds der Kameras zu Funktionsbeschrankungen, wahrend elektromagnetische Systeme durch ferromagnetisch aktive Materialien beeinflusst werden konnen. Die bisherigen Verfahren der Patientenregistrierun…

Das Cogan-I-Syndrom

2003

Wir berichten uber 2 Patienten, die seit dem Sauglings- und Kleinkindesalter unter einem Cogan-I-Syndrom leiden.Bei diesem seltenen Krankheitsbild handelt es sich um eine akute oder schubweise Verschlechterung der Horleistung des Innenohrs mit vestibularer Symptomatik und einer nichtsyphilitischen interstitiellen Keratitis oder anderen entzundlichen okularen Symptomen beim atypischen Cogan-I-Syndrom. Die erste Patientin erkrankte im 5.Lebensjahr an verschiedenen okularen Entzundungen, sodass ein Auge im 8.Lebensjahr erblindete.Zu dieser Zeit begann die Horverschlechterung. Im Alter von 17 Jahren litt die Patientin beidseits unter einer an Taubheit grenzenden Schwerhorigkeit. Bei dem zweiten…

Human papillomavirus infection and head and neck squamous cell carcinoma: current debates

2008

Multi-scale analysis of apparent diffusion coefficient (ADC) predicts cervical nodal status in patients with head and neck squamous cell carcinoma

2013

The study assess multi-scale diffusion parameters (median volumetric nodal region of interest values, inter-voxel histogram distributions, and intra-voxel diffusion heterogeneity as assessed by the stretched exponential model) as classifiers of nodal status in patients with head and neck squamous cell carcinoma (SCC). Low b value (0, 50, 100) derived nodal ADC (perfusion sensitive) was the key parameter facilitating discrimination of metastatic from benign nodes in patients with head and neck SCC. The stretched exponential derived α value together with histogram features of ADC provide an accurate decision tree model for classification of nodal disease.

Maximum likelihood ADC parameter estimates improve selection of metastatic cervical nodes for patients with head and neck squamous cell cancer

2012

The aim of this work was to determine whether classification of benign and metastatic cervical nodes based on diffusion weighted imaging (DWI) could be improved by use of a maximum likelihood algorithm for derivation of ADC parameters. A non linear least squares (LSQ) algorithm is usually used to fit parameters to the measured MR signal intensities as a function of b-value. LSQ assumes that the noise in high b-values is normally distributed whereas in reality it follows a Rice distribution. To account for the Rician noise, maximum likelihood (ML) algorithms have been proposed that provide unbiased ADC estimates. In this work the monoexponential, stretched exponential and biexponential model…

Radiomics Analyses of Schwannomas in the Head and Neck: A Preliminary Analysis

2022

The purpose of this preliminary study was to evaluate the differences in Magnetic Resonance Imaging (MRI)-based radiomics analysis between cerebellopontine angle neurinomas and schwannomas originating from other locations in the neck spaces. Twenty-six patients with available MRI exams and head and neck schwannomas were included. Lesions were manually segmented on the precontrast and postcontrast T1 sequences. The radiomics features were extracted by using PyRadiomics software, and a total of 120 radiomics features were obtained from each segmented tumor volume. An operator-independent hybrid descriptive‐inferential method was adopted for the selection and reduction of the features, while d…

Inflammatory Myofibroblastic Tumor of the Larynx: Case report.

2007

Inflammatory myofibroblastic tumors (IMT) of the larynx are uncommon lesions that easily may be misinterpreted as malignant epithelial or mesenchymal spindle cell neoplasms. When located in the upper airway, IMTs tend to be less aggressive, but have the potential for local invasion and recurrence. The authors describe a rare case of IMT in a 47 year old man, occurring in the vocal fold who underwent surgical treatment five times, because of its higher recurrence rate

Human papillomavirus-associated cancers: a survey on otorhinolaryngologists' knowledge and attitudes on prevention.

2016

Human papillomavirus (HPV) infection is a recognised causal factor associated with oropharyngeal cancers. The global burden of HPVrelated oropharyngeal cancers is on the increase and is predicted to surpass the burden of cervical cancer in the near future. As evidence is accumulating on the potential effectiveness of an HPV vaccine in controlling the oropharyngeal cancer epidemic; otorhinolaryngologists assume a key role - not only in the diagnosis and treatment of HPV-related cancers - but also in educating and advocating on HPV prevention. We conducted a survey to assess Italian otorhinolaryngologists' knowledge and attitudes regarding HPV infection, HPV-related oropharyngeal diseases and…

Swallowing Outcomes in Open Partial Horizontal Laryngectomy Type I and Endoscopic Supraglottic Laryngectomy: A Comparative Study

2022

Background: Effective swallowing represents the main challenge in supraglottic laryngectomy. This study aimed to assess swallowing outcome comparing endoscopic supraglottic laryngectomy (ESL) and open partial horizontal laryngectomy type I (OPHL I). Methods: A retrospective study was carried out on 20 patients that underwent supraglottic laryngectomy from 2015 to 2021: 10 underwent ESL (group A) and 10 underwent OPHL I (Group B). Patients underwent fiberoptic endoscopic evaluation of swallowing (FEES) 3 months and 12 months after surgery and videofluoroscopy swallowing studies (VFSS) 12 months after surgery. A Swallowing Outcome After Laryngectomy (SOAL) questionnaire was administered to pa…

Ultrasound hyperthermia induces apoptosis in head and neck squamous cell carcinoma: an in vitro study

2016

Background Hyperthermia is considered an efficient complement in the treatment of head and neck squamous cell carcinoma (HNSCC). Hyperthermia induces cell apoptosis in a temperature- and time-dependent manner. However, the molecular mechanism of hyperthermia remains unclear. The aim of this study was to investigate the mechanism of apoptosis induced by ultrasound hyperthermia in HNSCC cell lines HN-30 and HN-13. Material and Methods We examined the dynamic changes of early apoptosis and secondary necrosis in HN-30 and HN-13 cells treated by hyperthermia at 42°C for 10 min. We further examined mitochondrial membrane potential in vitro by ultrasound hyperthermia for different heating temperat…