Search results for "Head"

STUDIO DELLA BIODISTRIBUZIONE DI SOSTANZE BIOLOGICAMENTE ATTIVE IN ORGANISMI ACQUATICI

2022

Ancient Schwannoma of the hard palate. An uncommon case report and review

2013

Schwannoma or neurilemmoma is an infrequent benign tumor in the oral cavity that originates from the Schwann cells on the neural sheath of the peripheral nerves. Schwannomas are frequently located in the soft tissues of head and neck region, but only a 1 to 12% of them are located in the oral cavity. Some histological variants of schwannoma have been described including the cellular, plexiform, epithelioid, ancient, and melanocytic types. The “ancient schwannoma” is an uncommon variant of this tumor that shows specific histological characteristics, and is rare in the oral cavity with less than 15 cases described on the literature. Most of them were located in the tongue or in the floor of t…

Cesi, an early Middle Pleistocene site in the Colfiorito Basin (Umbro-Marchean Apennine), central Italy

1997

Near the village of Cesi, at the head of the Chienti River, in the Colfiorito Basin (Umbro-Marchean Apennines, central Italy), fluvio-lacustrine deposits have yielded mammal fossil remains. The results of a multidisciplinary investigation indicate that the vertebrate-bearing sediments date about 700 ka and accordingly provide a fossil assemblage for the Middle–Late Galerian. Palynological investigations carried out from sediments underlying the fossiliferous level suggest predominantly cold and dry conditions, whereas the fauna suggests a slight climatic amelioration towards cool and moist conditions in the uppermost part of the sequence. © 1997 John Wiley & Sons, Ltd.

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

2012

Wnt modulates glioma vascularization by regulating PDGF-B expression.

Immunohistochemical analysis of cancer-associated fibroblasts and podoplanin in head and neck cancer

2019

Background To immunohistochemically evaluate the association between the presence of cancer-associated fibroblasts (CAFs) and the tumour expression of podoplanin (PDPN) in head and neck squamous cell carcinoma (HNSCC) and their association with clinicopathological variables. Material and Methods A tissue microarray (TMA) with biopsy sections from patients diagnosed with HNSCC was stained with antibodies against the CAFs marker, α-smooth muscle actin (α-SMA), and PDPN. We subsequently evaluated their expression to determine the association between them and with clinicopathological variables including age, primary tumour site, TNM stage, and tumour differentiation grade. Results Positive reac…

Seizure in isolated brain cryptococcoma: Case report and review of the literature

2021

Background: Central nervous system (CNS) cryptococcosis is an invasive fungal infection predominantly seen among immunosuppressed patients causing meningitis or meningoencephalitis. Rarely, cryptococcosis can affect immunologically competent hosts with the formation of localized CNS granulomatous reaction, known as cryptococcoma. Common symptoms of CNS cryptococcoma are headaches, consciousness or mental changes, focal deficits, and cranial nerve dysfunction. Rarely, seizures are the only presenting symptom. Case Description: We report the case of an immunocompetent patient with a solitary CNS cryptococcoma presenting with a long history of non-responsive generalized seizure who has been s…

A possible inflammatory reaction in a lateral neck cyst (branchial cyst) because of odontogenic infection

1994

Abstract We present the case of a woman who suffered from an acutely infected diffuse mass in the right neck. This mass had grown rapidly after difficult extraction of a tooth. Histologic analysis of the excised material revealed a lateral neck cyst with a lymph node that showed signs of an acute inflammation near the cyst. These findings support the theory that a preexisting lateral neck cyst may be “activated” by an intraoral inflammation. The different theories of the origin of lateral neck cysts are presented and discussed in the context of the case description.

Ultrastructural localization of Ca2(+)-binding sites in the middle ear mucosa of the rat.

1990

Cations were precipitated with potassium-pyroantimonate in the middle ear mucosa of the rat and the distribution of the formed precipitates was studied by electron microscopy. The precipitate density in various cells of the different epithelia of the middle ear mucosa was determined on electron micrographs by counting the number of precipitates per unit area. Electron spectroscopic imaging was also performed to obtain information about the spatial distribution of the precipitates and their elemental composition.

Utility of imaging techniques in the diagnosis of oral cancer.

2015

Abstract Purpose Imaging techniques such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) are often used to complement the clinical exploration and staging of oral squamous cell carcinoma (OSCC). Which of these techniques is best in establishing correct staging and treatment planning is not clear, however. This study aims to determine which technique is most appropriate for diagnosing the primary tumor and for detecting bone invasion and neck metastases. Material and methods A Medline literature search was made over the last 10 years. In each selected study, we recorded the sample size and sensitivity, specificity and precision. Strengths…

An in vitro study showing the three-dimensional microenvironment influence over the behavior of head and neck squamous cell carcinoma

2011

Objectives: The Head and Neck Squamous Cell Carcinoma (HNSCC) ranks sixth worldwide. The mechanisms of growth, invasion and metastasis of this pathology are extensively studied and generally related to specific variations in signaling pathways like the PI3K-Akt; however most of these competent studies have been performed bidimensionally, which may hide important questions. This study sought to analyze the influence of the microenvironment upon the behavior of HNSCC. Study Design: The status of pAkt, NF-κB and Cyclin D1 proteins was accessed through immunofluorescence and western blot methods in HNSCC cell lines originating from tongue, pharynx and metastatic lymph node when submitted to a t…