Search results for "Heterocyclic compound"

showing 10 items of 382 documents

Clinical Nutrition Gr. AR

2021

Clinical Nutrition or Diet Therapy (prof. Teresa Climent) English revised by SPL UV Asignatura de tercero del grupo ARA del grado de Farmacia. Clinical Nutrition Grupo Ara (34110) Clinical Nutrition or Diet Therapy

carbohydrates (lipids)food and beveragesheterocyclic compoundslipids (amino acids peptides and proteins)biochemical phenomena metabolism and nutrition
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MLML2R

2019

R package for maximum likelihood estimation of DNA methylation and hydroxymethylation proportions.

carbohydrates (lipids)organic chemicalsbacteriaheterocyclic compoundsEpigeneticsMicroarray experimentMethylated DNA immunoprecipitation
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Synthesis of Lamellarin D Trimethyl Ether and Lamellarin H via 6π-Electrocyclization.

2015

An electrocyclic ring closure of a 2-azapentadienyl anion generated in situ from a chalcone and glycine ester is the key step of an efficient synthesis of the pyrrole core of the lamellarin alkaloids. A recently developed scalable one-pot procedure provides multigram quantities of a 3,5-diaryl-4-iodopyrrole-2-carboxylate intermediate which is transformed in four further high-yielding operations including a one-pot Pomeranz–Fritsch alkylation/cyclization and an Ullmann-type lactone ring closure into the pentacyclic lamellarin skeleton.

chemistry.chemical_classificationAnionsChalconeAlkylationMolecular StructureStereochemistryOrganic ChemistryEtherStereoisomerismStereoisomerismAlkylationRing (chemistry)IsoquinolinesHeterocyclic Compounds 4 or More Ringschemistry.chemical_compoundchemistryCoumarinsCyclizationLamellarin DPyrrolesLactonePyrroleEthersThe Journal of organic chemistry
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Mandelamide-zinc-catalyzed enantioselective alkyne addition to heteroaromatic aldehydes.

2006

The (S,S)-mandelamide III catalyzes the additions of both aryl- and alkylalkynylzinc reagents to heteroaromatic aldehydes with good yields and enantioselectivities up to 92%. This catalyst is easily prepared in a one-step procedure, and both enantiomers are available. Unlike most other described methods, using this catalyst does not require the addition of Ti(O(i)Pr)4.

chemistry.chemical_classificationArylOrganic ChemistryEnantioselective synthesischemistry.chemical_elementAlkyneGeneral MedicineZincAldehydeChemical synthesisCatalysischemistry.chemical_compoundchemistryHeterocyclic compoundReagentOrganic chemistryEnantiomerMandelamideThe Journal of organic chemistry
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Pentakis(dimethylzinn)diphosphid, struktur und kernresonanzspektren eines zinnreichen bicyclus

1979

Abstract Dehydrogenation of dimethylstannane combined with the hydrostannolysis of white phosphorus yields pentakis(dimethyltin) diphosphide, a tin-rich heterocyclic compound, which has the highly symmetric, bicyclic molecular structure of norbornane. Using the X-ray structure data the magnetic resonance spectra are discussed.

chemistry.chemical_classificationBicyclic moleculeStereochemistryWhite PhosphorusOrganic ChemistryBiochemistryMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundchemistryHeterocyclic compoundMaterials ChemistryMoleculeDehydrogenationPhysical and Theoretical ChemistryNorbornaneJournal of Organometallic Chemistry
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C1 Inhibitor-C1¯sComplexes Are Internalized and Degraded by the Low Density Lipoprotein Receptor-related Protein

1997

Like other serpin-enzyme complexes (SECs), proteinase-complexed C1 inhibitor (C1-INH) is rapidly cleared from the circulation and thought to be a neutrophil chemoattractant, suggesting that complex formation causes structural rearrangements exposing a domain which is recognized by specific cell surface receptors. However, the cellular receptor(s) responsible for the catabolism and potential mediation of chemotaxis by C1-INH-protease complexes remained obscure. To determine whether the SEC receptor mediates the binding and potential chemotaxis of C1-INH·C1s, we performed binding assays with HepG2 cells, neutrophils, and monocytes, and the results show that C1-INH·C1s neither bind to these ce…

chemistry.chemical_classificationCatabolismPeptideChemotaxisCell Biologybiochemical phenomena metabolism and nutritionrespiratory systemBiologybacterial infections and mycosesBiochemistryMolecular biologyrespiratory tract diseaseschemistry.chemical_compoundchemistryLow-density lipoproteinKnockout mouseLDL receptorheterocyclic compoundsAsialoglycoprotein receptorReceptorMolecular BiologyJournal of Biological Chemistry
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Effect of auxin on the mitotic cell cycle in cultured leaf segments at different stages of development in wheat

1987

Young leaves of Triticum timopheevi Zukh. show a defined gradient of development. One-mm-long sections from such leaves were cultured in vitro. At a low concentration of exogenous auxin, cells in the most basal, highly meristematic explants divided readily in culture, but in the absence of auxin they soon ceased dividing and were arrested in G1 and G2 of the mitotic cell cycle. In the region adjoining the meristem, where most cells were arrested in G1, very high concentrations of auxin had to be applied to reinitiate cell division, i.e. stimulate transitions from G1 to S-phase and from G2 to mitosis. Above this potentially auxin-responsive region, which represented less than 50% of the tota…

chemistry.chemical_classificationCell divisionPhysiologyfungifood and beveragesCell BiologyPlant ScienceGeneral MedicineCell cycleMeristemBiologyCell biologyTissue cultureMitotic cell cycleBiochemistrychemistryAuxinGeneticsheterocyclic compoundsMitosisExplant culturePhysiologia Plantarum
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Stereoselective Synthesis and Structural Correction of the Naturally Occurring Lactone Stagonolide G

2010

A convergent synthesis of the structure proposed for the naturally occurring lactone stagonolide G is described. All three stereocenters were created with the aid of asymmetric Brown allylations. The lactone ring was built by means of a ring-closing metathesis (RCM). The synthetic and the natural compound differed in their spectral properties. A new structure is now proposed for stagonolide G and demonstrated by means of a chemical transformation.

chemistry.chemical_classificationChemical transformationMolecular StructureChemistryStereochemistryOrganic ChemistryConvergent synthesisStereoisomerismStereoisomerismMetathesisRing (chemistry)BiochemistryCatalysisStereocenterHeterocyclic Compounds 1-RingLactonesStereoselectivityPhysical and Theoretical ChemistryLactoneOrganic Letters
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Lewis Acid-Catalyzed Stereoselection on Carbohydrate Templates

1989

The chirality and the complexing abilities of carbohydrates are utilized for chemical stereoselection in different reactions. In this sense, the carbohydrates are investigated as the chiral auxiliaries in alkylation reactions and in Michael additions of ester enolates. Furthermore, carbohydrates are demonstrated to be efficient chiral matrices in Lewis acid-catalyzed Diels-Alder reactions. They also effect stereoselection in a new synthesis of β-branched carboxylic acid derivatives. O-Acylated glycosylamines are shown to be potent chiral templates in the Strecker synthesis and in the Ugi four-component condensation to give α-amino acid derivatives in high yield and diastereoselectivity. In …

chemistry.chemical_classificationChiral auxiliaryorganic chemicalsCarboxylic acidStrecker amino acid synthesisAlkylationCatalysischemistry.chemical_compoundchemistryYield (chemistry)Organic chemistryheterocyclic compoundsLewis acids and basesChirality (chemistry)
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Über die Verbreitung von Flavonoiden bei pleurokarpen Laubmoosen II. Apigenin and Apigenin-7-rhamnoglucosid bei Pleurozium schreberi (Willd.) Mitt.

1980

Summary 12 species of pleurocarpous mosses have been investigated as to their content of flavonoids. Flavonoid tests on 11 species have given negative results. Only one species, Pleurozium schreberi , contains three flavonoids. They were purified by means of paper chromatography. Two of them are by chromatography, acid hydrolysis and absorption spectrum identical with apigenin and apigenin-7-rhamnoglucoside. The third flavonoid is as yet unidentified. Qualitative hydrolysis yields apigenin. The chemotaxonomic importance of the results is briefly discussed.

chemistry.chemical_classificationChromatographybiologyfungiFlavonoidfood and beveragesGeneral Medicinebiology.organism_classificationcarbohydrates (lipids)Paper chromatographyHydrolysischemistry.chemical_compoundchemistryApigeninheterocyclic compoundsAcid hydrolysisPleurozium schreberiZeitschrift für Pflanzenphysiologie
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