Search results for "Hf"
showing 10 items of 909 documents
The HERMES-Technologic and Scientific Pathfinder
2020
HERMES-TP/SP (High Energy Rapid Modular Ensemble of Satellites Technologic and Scientific Pathfinder) is a constellation of six 3U nano-satellites hosting simple but innovative X-ray detectors, characterized by a large energy band and excellent temporal resolution, and thus optimized for the monitoring of Cosmic High Energy transients such as Gamma Ray Bursts and the electromagnetic counterparts of Gravitational Wave Events, and for the determination of their positions. The projects are funded by the Italian Ministry of University and Research and by the Italian Space Agency, and by the European Union Horizon 2020 Research and Innovation Program under Grant Agreement No. 821896. HERMES-TP/S…
Specific Irreversible Cell-Cycle Arrest and Depletion of Cancer Cells Obtained by Combining Curcumin and the Flavonoids Quercetin and Fisetin.
2022
Background: Induced senescence could be exploited to selectively counteract the proliferation of cancer cells and target them for senolysis. We examined the cellular senescence induced by curcumin and whether it could be targeted by fisetin and quercetin, flavonoids with senolytic activity. Methods: Cell-cycle profiles, chromosome number and structure, and heterochromatin markers were evaluated via flow cytometry, metaphase spreads, and immunofluorescence, respectively. The activation of p21waf1/cip1 was assessed via RT-qPCR and immunoblotting. Senescent cells were detected via SA-β-Galactosidase staining. Results: We report that curcumin treatment specifically triggers senescence in cancer…
Quantitative approaches for evaluating the influence of films using the IMDb database
2016
[EN] Why do films certain remain influential throughout film history? The purpose of this paper is to attempt to answer this question. To do so, we adopt some quantitative approaches that facilitate an objective interpretation of the data. The data source we have chosen for this study is the Internet Online Movie Database (IMDb), and in particular, one of its sections called "Connections", which lists references made to a film in subsequent movies and references made in the film itself to previous ones. The extraction and analysis of these networks of citations allows us to draw some conclusions about the most influential movies in film history, identifying their distinguishing features, an…
Fast noniterative orbital localization for large molecules
2006
We use Cholesky decomposition of the density matrix in atomic orbital basis to define a new set of occupied molecular orbital coefficients. Analysis of the resulting orbitals ("Cholesky molecular orbitals") demonstrates their localized character inherited from the sparsity of the density matrix. Comparison with the results of traditional iterative localization schemes shows minor differences with respect to a number of suitable measures of locality, particularly the scaling with system size of orbital pair domains used in local correlation methods. The Cholesky procedure for generating orthonormal localized orbitals is noniterative and may be made linear scaling. Although our present implem…
Fine slicing of the value chain and offshoring of essential activities: empirical evidence from European multinationals
2014
The offshoring of more advanced activities is increasing and a debate about the limits of offshoring has emerged. Companies are fine-slicing their value chains, and moving beyond the offshoring of peripheral and non-core activities to the offshoring of advanced and essential activities that are closer to their core (e.g. research, design and product development). The challenge is to understand the limits of offshoring and the most appropriate modes of offshoring. The purpose of this paper is to analyze what activities are offshorable and how best to govern offshored activities. We argue that companies are redefining their core activities and in this process, some essential activities previo…
PIRACY REVISITED: EXPLORING MUSIC USERS IN THE AGE OF TECHNOLOGY DEPENDENCY
2019
This paper empirically investigates and characterizes users of recorded music, both downloaders and purchasers. To this end we analyse the role of the variables defining the different segments of music users. In doing so, we have considered two main traits influencing the use of music. First, objective variables such as demographics, music consumption habits, music genres and technology. Second, subjective variables such as motives and attitudes towards piracy. Using data from a personal survey, subsequent latent class and fuzzy analyses show that while the former characteristics are relevant in those getting music for free from the Internet, the latter don´t pay any special part, contrary …
Main components of the corporative image of cultural organizations
2016
[EN] In the present research, we carry out an analysis of the corporate image of a cultural organization which aims tohighlight its role in order to design management strategies in the cultural field. We investigate what particular attributes are better assessed by the public and which dimensions compose the corporate image of a cultural organization. Based on the literature review, we made an in-depth interview to the programming manager of a cultural organization and also a descriptive survey on its audience through a structured questionnaire.The results of the analyses show that the corporate image of the cultural organization under study is positive, although someattributescan be improv…
Orthotropic plate dynamics by a novel meshfree method
2003
Publisher Summary This chapter deals with a novel meshfree method for the dynamic analysis of orthotropic plates under the Kirchhoff small deflection theory. The approach starts from a modified function whose stationarity conditions lead to the meshfree plate dynamic model through a discretization process—based on the use of orthotropic plate static fundamental solutions. The resolving system obtained is characterized by—frequency independent stiffness and mass matrices, which preserve the symmetry and definiteness properties of the continuum. Moreover, these operators are computed by boundary integrals of regular kernels. The method allows the application of standard numerical routines ava…
Durable Rural Development Through the 2014 - 2020 National Rural Development Program
2018
Abstract Rural Development Policy is a priority for the E.U., as half of the Union’s population lives in rural areas. This policy is focused on society’s durable development, under all its aspects: economic, social, cultural, and so on. The challenges which rural areas of member states face must be addressed, while at the same time applying European norms and standards for rural development. After Romania became a part of the E.U., rural areas here were supported through several national rural development programs, so as to create a durable and sustainable rural economy. Major changes are required to achieve this kind of development, such as replacing old agricultural structures, modernizin…
La dittatura dei diritti indisponibili
2014
In questo articolo discuto il tema dei diritti indisponibili diritti che devono essere esercitati