Search results for "Hub"
showing 10 items of 207 documents
Caractérisation cytomique de cellules transformées de tabacs exprimant le domaine « hub » de la chaîne lourde de la clathrine
2018
ARES. III. Unveiling the Two Faces of KELT-7 b with HST WFC3
2020
We present the analysis of the hot-Jupiter KELT-7b using transmission and emission spectroscopy from the Hubble Space Telescope (HST), both taken with the Wide Field Camera 3 (WFC3). Our study uncovers a rich transmission spectrum which is consistent with a cloud-free atmosphere and suggests the presence of H2O and H-. In contrast, the extracted emission spectrum does not contain strong absorption features and, although it is not consistent with a simple blackbody, it can be explained by a varying temperature-pressure profile, collision induced absorption (CIA) and H-. KELT-7 b had also been studied with other space-based instruments and we explore the effects of introducing these additiona…
A Visitor of Tropical Waters: First Record of a Clymene Dolphin (Stenella clymene) Off the Patagonian Coast of Argentina, With Comments on Diet and M…
2021
The poorly known Clymene dolphin (Stenella clymene) is a small oceanic cetacean distributed in tropical and subtropical waters of the Atlantic Ocean. In this study, we report, for the first time, a vagrant individual of Clymene dolphin in Argentina (Rada Tilly) that represents the current southern-most record for this cetacean species. We provide a molecular identification of the dolphin, based on partial sequences of the mitochondrial cytochrome b gene, generated from DNA extracted from its metazoan parasites. Three prey species, namely Argentine hake, Patagonian squid and lobster krill were identified from hard pieces collected in the stomach. Seven metazoan parasite taxa (three in adult …
Contributions to Branch-and-Price-and-Cut Algorithms for Routing Problems
2019
This article deals with new exact branch-and-price-and-cut algorithms for the solution of routing problems. Specialized methods for the pickup-and-delivery problem (PDP), the truck-and-trailer routing problem (TTRP), the periodic vehicle routing problem (PVRP) and a service network design and hub location problem (SNDHLP) are presented. We develop a new technique for the acceleration of bidirectional labeling algorithms by a dynamic choice of the merge point. Moreover, for variants of the PDP, the bidirectional labeling can be effectively applied for the first time. In the TTRP, we model the extension to a 2 days planning horizon and the consideration of a quantity-dependent transfer time. …
Branch-and-price-and-cut for a service network design and hub location problem
2015
In the context of combined road-rail freight transport, we study the integrated tactical planning of hub locations and the design of a frequency service network. We consider a number of real-world constraints such as multiple transshipments of requests at hubs, transport time limits for requests, request splitting, and outsourcing possibilities. To our knowledge, the combination of problem features we deal with has not been described before. We present a path-based model and solve it with a branch-and-price-and-cut algorithm. Computational experiments show that large realistic instances from a major German rail freight company can be solved close to optimality within one hour on a standard …
Reflexiones a propósito de la protección de datos en el escenario global digital: El derecho de daños en la litigiosidad internacional
2021
La circulación internacional de datos personales constituye un sector pujante en la esfera socio-económica. En tales condiciones, ante la existencia de un tratamiento ilícito de aquellos, el agraviado está legitimado para exigir una indemnización por los daños y perjuicios que se hubieran podido originar en el marco transfronterizo. Tal situación plantea dos cuestiones fundamentales: por un lado, determinar el órgano jurisdiccional competente para conocer de un eventual litigio, y, por otro, precisar la Ley aplicable para resolver la controversia suscitada. En la presente investigación cabe destacar las significativas novedades que introduce el Reglamento (UE) 2016/679, de 27 de abril de 20…
NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies
2013
Chronic inflammation is a major biological mechanism underpinning biological ageing process and age-related diseases. Inflammation is also the key response of host defense against pathogens and tissue injury. Current opinion sustains that during evolution the host defense and ageing process have become linked together. Thus, the large array of defense factors and mechanisms linked to the NF-κB system seem to be involved in ageing process. This concept leads us in proposing inductors of NF-κB signaling pathway as potential ageing biomarkers. On the other hand, ageing biomarkers, represented by biological indicators and selected through apposite criteria, should help to characterize biologica…
Chronic Non-cancer Pain Management in a Tertiary Pain Clinic Network: a Retrospective Study
2022
Introduction: Chronic pain is a distressing condition that should be treated in specialized pain clinics. Pain clinics offer a holistic, evidence-based approach, including pharmacological, complementary, and invasive treatments. This study aimed to provide preliminary information regarding chronic pain treatments and identify reasons for accessing an important hub-spoke pain clinic network. Methods: A retrospective multicenter cross-sectional study was carried out. A total of 1606 patients’ records were included. Patients were selected from the 26 pain clinics of a single region in Italy. Univariate and multivariate logistic regression models were used. Results: Multivariate models showed t…
Energy management of multi-carrier smart buildings for integrating local renewable energy systems
2016
The proposed paper aims at defining a Building Management System (BMS) able to control energy flows inside a smart building integrated with various energy networks and Renewable Energy Resources (RES). The smart building envisaged in this work interacts with different energy carriers and is equipped with cogeneration and RES systems, as well as storage devices, which enable a certain degree of flexibility in the energy usage. The smart building is modelled as a multi-carrier hub, by defining the graphical and mathematical model of the building system. Moreover, the control criteria of the BMS are explained and the implementation of the BMS itself is depicted, along with some early results. …
Dark coupling and gauge invariance
2010
We study a coupled dark energy–dark matter model in which the energymomentum exchange is proportional to the Hubble expansion rate. The inclusion of its perturbation is required by gauge invariance. We derive the linear perturbation equations for the gauge invariant energy density contrast and velocity of the coupled fluids, and we determine the initial conditions. The latter turn out to be adiabatic for dark energy, when assuming adiabatic initial conditions for all the standard fluids. We perform a full Monte Carlo Markov Chain likelihood analysis of the model, using WMAP 7-year data.