Search results for "Human Immunodeficiency Virus"

ROUTES OF HIV-2 TRANSMISSION IN WESTERN EUROPE

1987

Autoeficacia en la prevención sexual del Sida: la influencia del género

2013

Title: Self-efficacy in AIDS sexual prevention: influence of gender. Abstract: The scientific literature suggests that a low self-efficacy for con- dom use may be related to many risky behaviors for HIV transmission in young people. We analyze the self-efficacy of condom use among youth, the existence of gender differences and the relationship with other relevant variables in HIV prevention. The "Self-Efficacy Condom Use Subscale", included in the AIDS Prevention Questionnaire (Ballester, Gil and Gimenez, 2007), was administrated to 3540 university students (50.9% women, 49.1% men). The results showed that the sample obtained medi- um-high scores on self-efficacy, showing the lowest scores …

Características sociales y clínicas de un grupo de madres infectadas por VIH en Valencia: influencia de la drogadicción parenteral

2000

Resumen Objetivo Al principio de conocerse la infeccion por el virus de la inmunodeficiencia humana (VIH), la causa mas importante de su transmision en las mujeres occidentales fue el consumo de drogas por via parenteral. El objetivo de nuestro trabajo consistio en describir las principales caracteristicas sociales y clinicas de un grupo de madres seropositivas, y en analizar su relacion potencial con el uso intravenoso de drogas. Metodos Realizamos un estudio observacional prospectivo con 220 mujeres infectadas por VIH que presentaban la particularidad de haber dado a luz ninos con riesgo de infeccion. Se incluyeron todas las madres reclutadas en la Unidad VIH de un hospital de Valencia qu…

Expression and cellular localization of the Nef protein from human immunodeficiency virus-1 in stably transfected B-cells.

1992

Nef protein, encoded by the regulatory nef gene of human immunodeficiency virus type 1 (HIV-1), was expressed in the B-cell line Raji. The cells were stably transfected with plasmids containing the nef transcriptional cassette. They expressed Nef with an Mr of 27,000; the yield could be augmented by incubation with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. The intracellular localization of Nef was analyzed applying immunofluorescence microscopy using a confocal laser scanning microscope. The antigen was stained with a monoclonal antibody directed against the N-terminal part of Nef. The experiments revealed that in non-dividing cells Nef is present both in the cytoplasm and th…

A Shock to the System: HIV among Older African Women in Zimbabwe

2018

HIV remains a threat to the ordinary everyday life of older woman in African society. In what can be called “a reality shock,” HIV challenges most of the ordinary everyday endeavors in conservative African societies as it imposes new Western prevention, treatment, and health-management methods over long-held African traditions. The reality of the “Western” HIV epidemic, and its impact on the “African” ordinary everyday life, demands that the infected undergo a paradigm shift in order for them to live harmoniously within their society. This calls for a re-examination of traditional values and a strong sense of responsibility, courage, and determination to remain relevant and not be considere…

Durability of Dolutegravir-Based Regimens: A 5-Year Prospective Observational Study

2021

This study evaluates the frequency and causes of dolutegravir (DTG) discontinuation along 5 years of follow-up, in both antiretroviral treatment (ART)-naive and experienced people living with HIV (PLWH). This is a prospective multi-center cohort study enrolling PLWH on DTG from July 2014 until November 2020. DTG-durability was investigated using the Kaplan-Meier survival curve. The Cox proportional-hazards model was used for estimating the hazard ratio (HR) of DTG discontinuation for any cause, and for adverse events (AEs). Nine hundred sixty-three PLWH were included, 25.3% were women and 28.0% were ART-naive. Discontinuations for any causes were 10.1 [95% confidence interval (95% CI) 8.9-1…

Syntheses of Some Biologically Active Compounds from Stilbenes Isolated from the Bark ofPicea abies

1992

From the four stilbenes 1–4 isolated from the bark of Picea abies seven compounds 5–11 were obtained by hydrogenation or permethylation. 1H-, 13C-NMR and mass spectra were used for their characterization. The antileukemic activity of each compound was preliminary tested. Some compounds were further tested for their anti-HIV activity.

Autoimmune Hemolytic Anemia and Human Immunodeficiency Virus (HIV) Infection

1988

Excerpt To the editor:In patients with human immunodeficiency virus (HIV) infection, normochromic-normocytic anemia is common (1). Only four cases of autoimmune hemolytic anemia have been reported ...

The Level of Cytokeratin 18 in Patients with HIV and Viral Hepatitis C Co-Infection in Latvia

2020

Abstract Cytokeratin 18 (CK18) is a specific marker of hepatocellular apoptosis, which is a useful noninvasive indicator of liver fibrosis in the HIV/HCV group. However, data on the CK18 level in serum are limited for this group. This study demonstrated CK18 levels in serum in HIV/HCV co-infected and HIV mono-infected patients; investigated the association of CK18 levels with other non-invasive markers of liver fibrosis; and presents CK18 dynamics in a four-month-long period. The sample included 273 patients with HIV infection (128 of them were with HIV/HCV co-infection) aged from 23 to 65 (35% females). Levels of hyaluronic acid, CK18, ALT, and AST were determined in serum, and the FIB4 in…

HIV Infection in 403 Female Prostitutes in Italy

1991

Since the beginning of HIV epidemic, it became clear that the modality of transmission was different between Western Countries and Africa (1). Infact, in Africa heterosexual contact is the most important factor in the spread of HIV infection and female prostitutes are considered to be the major reservoir of HIVinfection (2).