Search results for "Humor"

Eurípides, Helena 435-482. Elementos conversacionales, humor y guiños aristofánicos en una tragedia

2010

En este artículo el autor trata de estudiar en detalle los elementos conversacionales de un conocido pasaje de la Helena de Eurípides, su connatural asiento en la dicción de la tragedia, su interacción con algunos elementos humorísticos, los problemas que esto plantea y la ponderación de todo ello con una visión ecléctica. Se llega a la conclusión de que Eurípides introduce humor y guiños a la Comedia aristofánica en este caso y que, gracias a su talento dramático, no desvirtúa la esencia de la tragedia. This paper deals with a detailed study of conversational idioms in a well-known scene of Euripides’ Helen, their connatural place in the diction of tragedy, their interaction with some humo…

The interaction of codes in dubbing: wordplay and visual restrictions

2012

The following paper delves into the complex transfer of humour focusing on a recurring problem that appears when dubbing comedies: wordplay partially transmitted by image. It analyses the factors that have a bearing on translation and illustrates the various translation techniques with scenes from the Marx Brothers' filmography. Finally, it details the conclusions obtained from the analysis of the dubbing of 74 puns with visual restriction and its comparison with 116 cases where there is no such restriction.

En torno al humorismo de Augusto Monterroso

2013

The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses.

2011

Abstract Lymphnode swelling during immune responses is a transient, finely regulated tissue rearrangement, accomplished with the participation of the extracellular matrix. Here we show that murine and human reactive lymph nodes express SPARC in the germinal centres. Defective follicular dendritic cell networking in SPARC-deficient mice is accompanied by a severe delay in the arrangement of germinal centres and development of humoral autoimmunity, events that are linked to Th17 development. SPARC is required for the optimal and rapid differentiation of Th17 cells, accordingly we show delayed development of experimental autoimmune encephalomyelitis whose pathogenesis involves Th17. Not only h…

DNA-mediated immunization to hepatitis B virus envelope proteins: preS antigen secretion enhances the humoral response.

1999

In order to design optimized DNA vectors as genetic vaccines against infections with the hepatitis B virus (HBV) we investigated if secretion or retention of the viral antigens has an influence on the quality and quantity of the humoral immune response. Intramuscular injection of plasmid DNA encoding the HBV large L envelope protein, known to be retained within host cells, induced only a weak response in mice whereas a vector expressing the secretion-competent small S envelope protein elicited strong and sustained immunity. Immunization with rearranged envelope genes further demonstrated that secretion affects the magnitude of the immune response. In situ expression of modified small and mi…

Analogous IgG subclass response to pertussis toxin in vaccinated children, healthy or affected by whooping cough

2003

The study of antigen specific IgG subclass distribution during disease, or during any other natural or artificial immunisation, can provide useful information on the kind of the immune response and the expected levels of protection. This is particularly true for diseases, such as pertussis in which the mechanisms underlying specific defence are still not completely understood. An investigation was therefore performed to evaluate the IgG subclass response to pertussis toxin (PT) in sera from 89 healthy vaccinated children and 131 vaccinated or unvaccinated children convalescent after a confirmed B. pertussis symptomatic infection. Antibody titres were expressed in arbitrary ELISA units/ml, a…

A trifunctional dextran-based nanovaccine targets and activates murine dendritic cells, and induces potent cellular and humoral immune responses in v…

2013

Dendritic cells (DCs) constitute an attractive target for specific delivery of nanovaccines for immunotherapeutic applications. Here we tested nano-sized dextran (DEX) particles to serve as a DC-addressing nanocarrier platform. Non-functionalized DEX particles had no immunomodulatory effect on bone marrow (BM)-derived murine DCs in vitro. However, when adsorbed with ovalbumine (OVA), DEX particles were efficiently engulfed by BM-DCs in a mannose receptor-dependent manner. A DEX-based nanovaccine containing OVA and lipopolysaccharide (LPS) as a DC stimulus induced strong OVA peptide-specific CD4(+) and CD8(+) T cell proliferation both in vitro and upon systemic application in mice, as well a…

Circulating specific antibodies enhance systemic cross-priming by delivery of complexed antigen to dendritic cells in vivo

2012

Increasing evidence suggests that antibodies can have stimulatory effects on T-cell immunity. However, the contribution of circulating antigen-specific antibodies on MHC class I cross-priming in vivo has not been conclusively established. Here, we defined the role of circulating antibodies in cross-presentation of antigen to CD8(+) T cells. Mice with hapten-specific circulating antibodies, but naϊve for the T-cell antigen, were infused with haptenated antigen and CD8(+) T-cell induction was measured. Mice with circulating hapten-specific antibodies showed significantly enhanced cross-presentation of the injected antigen compared with mice that lacked these antibodies. The enhanced cross-pre…

Recombinant virus-like particles of a norovirus (genogroup II strain) administered intranasally and orally with mucosal adjuvants LT and LT(R192G) in…

2003

We investigated the immune response induced by mucosal immunization of BALB/c mice with virus-like particles (VLPs) of a genogroup II norovirus, Dijon171/96 virus, produced in the baculovirus system. VLPs administered alone by the intranasal route induced a high serum antibody response as well as fecal IgA, which were enhanced when the heat-labile Escherichia coli toxin or its non toxic mutant LT(R192G) was coadministered. In these conditions, the oral route was also efficient. Cytokine production by cells from different lymphoid tissues was then assessed after in vitro restimulation. A Th1/Th2-like response was observed in cervical lymph node and Peyer's patch (PP) cell cultures from mice …

The link between induced emotions, the humor style and the sense of life quality

2015

The study showed that there is a link between induced emotions, the humor style and the sense of life quality. According to Martin’s [1] theory stating that there are four humor styles: affiliative, self-enhancing, aggressive and self-defeating, the humor style of people belonging to groups in which one of the following emotions: sadness, aversion, satisfaction and joy, had earlier been induced and the control group was checked by means of the Humor Styles Questionnaire (HSQ). Moreover, in case of each analyzed group,the level of the sense of life quality was measured. The results of this analysis show that the fact of inducing such emotions as joy or sadness is connected with decreasing or…