Search results for "IAC"

showing 10 items of 4189 documents

Stem cell populations in the heart and the role of Isl1 positive cells

2013

Cardiac progenitor cells are multipotent stem cells isolated from both embryonic and adult hearts in several species and are able to differentiate at least into smooth muscle cells, endothelial cells and cardiomyocytes. The embryonic origin of these cells has not yet been demonstrated, but it has been suggested that these cells may derive from the first and secondary heart fields and from the neural crest. In the last decade, two diffe-rent populations of cardiac progenitor or stem cells have been identified and isolated, i.e., the Islet1 positive (Isl1+) and c-Kit positive (c-Kit+)/Stem Cell Antigen-1 positive (Sca-1+) cells. Until 2012, these two populations have been considered two separ…

lineagesHistologymuscleLIM-Homeodomain ProteinsBiophysicscardiac progenitor cellsheartBiologycardiac progenitor cells stem cells heart lineages biology muscle.stem cellsHumansProgenitor celllcsh:QH301-705.5Induced stem cellsViews and CommentsbiologySettore BIO/16 - Anatomia UmanaMyocardiumCell BiologyCell biologyEndothelial stem cellP19 celllcsh:Biology (General)Gene Expression RegulationMultipotent Stem CellAmniotic epithelial cellsImmunologycardiac progenitor cells stem-cells heart lineages biology muscle.Stem cellAdult stem cellTranscription Factors
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Usare il presente per spiegare il passato. Teorie linguistiche contemporanee e lingue storiche

2012

In che misura ipotesi teoriche e nuovi metodi dell'attuale linguistica sincronica possono giocare un ruolo sull'indagine diacronica delle lingue? Con che incidenza dati e acquisizioni dell'indagine diacronica delle lingue possono avere delle ricadute sul modo di fare linguistica sincronica? A queste domande si è impegnata la discussione all'interno del XXXIII convegno della Società Italiana di Glottologia di cui il volume raccoglie gli Atti.

linguistica diacronica linguistica sincronica metodi a confrontoSettore L-LIN/01 - Glottologia E Linguistica
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Tradizione e ricezione musicale dei più antichi testi lirici italiani: a proposito di un libro recente

2007

lirica italiana medievale tradizione stravagante Carta ravennate Frammento piacentino musica
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Sobre l’originalitat del Cours de Linguistique Générale de Ferdinand de Saussure

2017

A partir de la revisió d’alguns dels dualismes formulats com a dicotomies al Cours de Linguistique Générale, es valoren en aquest treball les suposades innovacions saussureanes, tot atenent als seus antecedents en la història de la lingüística i a les repercussions en el posterior desenvolupament de la ciència del llenguatge. Based on the revision of some of the dualisms formulated as dichotomies in the Cours de Linguistique Générale, the assumptions Saussurean innovations are valued in this work, taking into account their background in the history of linguistics and the repercussions in the later development of the language science.

llenguasincronia:LINGÜÍSTICA [UNESCO]Saussure; llengua; parla; signe lingüístic; sincronia; diacroniadiacroniaSaussureparlasigne lingüísticUNESCO::LINGÜÍSTICA
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A minireview on NHE1 inhibitors. A rediscovered hope in oncohematology.

2015

Background: Na+/H+ exchanger-1 (NHE-1) is involved in pH regulation and is up-regulated in different malignancies. Activation of NHE-1 is one way for allowing cells to avoid intracellular acidification and protect them against apoptosis. Inhibitors of NHE-1 are able to decrease intracellular pH and induce apoptosis. Some statins can also act by partial inhibition of NHE-1. This review presents progress in understanding the mechanisms of action of these inhibitors, connections with certain genetic mutations and acquired treatment resistance, as well as new patents on them. Methods: A MEDLINE search for original and review articles using key terms, Na+/H+ exchanger, leukemia, cariporide, and …

lovastatinlcsh:MedicineApoptosisPharmacologyGuanidinesAmiloridep-glycoproteinhemic and lymphatic diseasesDrug InteractionsSulfonesCation Transport ProteinsSodium-Hydrogen Exchanger 1leukemiaMyeloid leukemiaHydrogen-Ion ConcentrationSorafenibUp-RegulationLeukemiaLeukemia Myeloid AcuteImatinib MesylateSignal transductionTyrosine kinasemedicine.drugSignal TransductionSorafenibNiacinamideisoprenylationSodium-Hydrogen Exchangersbcr/ablAntineoplastic AgentsGenes ablGeneral Biochemistry Genetics and Molecular BiologystatinsPatents as TopicCell Line TumorLeukemia Myelogenous Chronic BCR-ABL PositivemedicineHumansProtein Kinase Inhibitorscariporidena+/h+ exchangerTumor hypoxiabusiness.industryPhenylurea Compoundslcsh:ROsmolar Concentrationintracellular phmedicine.diseaseImatinib mesylatefms-Like Tyrosine Kinase 3Fms-Like Tyrosine Kinase 3MutationCancer researchTumor Hypoxiaflt3/itdHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessHeme Oxygenase-1DNA DamageBiomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
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Triacylglycerol Analysis in Human Milk and Other Mammalian Species: Small-Scale Sample Preparation, Characterization, and Statistical Classification …

2015

In this work, a method for the separation of triacylglycerols (TAGs) present in human milk and from other mammalian species by reversed-phase high-performance liquid chromatography using a core–shell particle packed column with UV and evaporative light-scattering detectors is described. Under optimal conditions, a mobile phase containing acetonitrile/n-pentanol at 10 °C gave an excellent resolution among more than 50 TAG peaks. A small-scale method for fat extraction in these milks (particularly of interest for human milk samples) using minimal amounts of sample and reagents was also developed. The proposed extraction protocol and the traditional method were compared, giving similar results…

mammalian milk triacylglycerolslinear discriminant analysisResolution (mass spectrometry)HPLC-ELSDBiologyHigh-performance liquid chromatographyMass SpectrometryChromatography detectorAnimalsHumansSample preparationChromatography High Pressure LiquidTriglyceridesfat extractionPacked bedChromatography Reverse-PhaseChromatographySheepMilk HumanGoatsExtraction (chemistry)human milkDiscriminant AnalysisGeneral ChemistryStatistical classificationMilkComposition (visual arts)CattleFemaleGeneral Agricultural and Biological SciencesJournal of agricultural and food chemistry
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A network of Spanish consecutive discourse markers from a usage-based perspective: corpus and experimental evidences

2022

Esta tesis se plantea la necesidad de describir las diferencias entre determinados sintagmas preposicionales y marcadores del discurso y de representar cómo estas se reflejan en un cline evolutivo, donde la primera categoría avanza gradualmente hacia la segunda. Una premisa fundamental del trabajo consiste en que el esquema sincrónico conformado por unidades que comparten origen composicional y muestran, en cambio, diferentes propiedades formales o funcionales nos proporciona un marco fiable del proceso diacrónico que han recorrido. En este sentido, las unidades consecutivas del español por eso, por ello y por esto han sido frecuentemente diferenciadas del marcador del discurso por tanto en…

marcadores del discursogramática de construccionesUNESCO::LINGÜÍSTICA::Lingüística diacrónica::Lingüística histórica:LINGÜÍSTICA [UNESCO]construccionalizaciónUNESCO::LINGÜÍSTICA::Lingüística sincrónica:LINGÜÍSTICA::Teoría lingüística [UNESCO]:LINGÜÍSTICA::Lingüística sincrónica [UNESCO]UNESCO::LINGÜÍSTICA:LINGÜÍSTICA::Lingüística diacrónica::Lingüística histórica [UNESCO]gramaticalizaciónUNESCO::LINGÜÍSTICA::Teoría lingüística
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Procesos de subjetivación, mediación tecnológica y educación matemática en Zipaquirá- Colombia

2023

A lo largo de la historia de la educación, el foco de su atención ha cambiado desde el establecimiento de poderes, pasando por los contenidos, hasta llegar al estudiante como centro del proceso; aunque todas las naciones no se encuentren en el mismo periodo. En este escenario, el papel de la tecnología en la escuela también ha evolucionado; partiendo de la falta de acceso a equipos y servicios, situación que aún prevalece en muchas regiones, hasta el logro de una integración en donde la tecnología es el mejor medio de aprendizaje de la matemática ya que reconoce y motiva al estudiante. Es así como el estudio relaciona conjuntamente procesos de subjetivación, mediación tecnológica y educació…

matemáticamediación tecnológicasubjetivacióneducaciónUNESCO::PEDAGOGÍAUNESCO::MATEMÁTICAS
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Mācību motivācijas veicināšana matemātikas stundās apvienotajā 1.-3. klasē ar M.Montesori metodes apmācību

2020

Bakalaura darba autore: Diāna Vatuļina. Bakalaura darba vadītājs: asoc. Prof. Jānis Mencis. Bakalaura darba temats: mācību motivācijas veicināšana matemātikas stundās apvienotajā 1.-3. klasē ar M.Montesori metodes apmācību. Pētījuma mērķis: pētīt 1.-3. klašu skolēnu motivācijas veidošanās faktorus un noskaidrot iespējas motivācijas veicināšanai matemātikas stundās apvienotajā klasē ar M. Montesori metodes apmācību. Pētījuma uzdevumi: 1.Analizēt teorētiskās un pedagoģiskās atziņas par mācību motivāciju un to pielietojumu. 2.Izstrādāt apvienotās 1-3. klases mācību motivācijas vērtēšanas kritērijus matemātikas stundās. 3.Veikt pētījumu par mācību motivācijas veicināšanu matemātikas stundās apv…

matemātikamotiviacijaSkolas pedagoģija1.- 3. klaseM.Montesori
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L'eiaculazione precoce: profili giuridici

2021

L’eiaculazione precoce presenta degli aspetti di indubbio rilievo canonistico, in quanto può non solo costituire (in un rapporto di concorrenza o di alternanza) una possibile causa della mancata consumazione del matrimonio o della sua nullità per impotenza maschile, ma può rilevare anche sotto diversi altri profili. L'eiaculazione precoce – oltre a potere provocare lo scioglimento del matrimonio per inconsumazione ex can. 1142 – si presta ad una molteplice chiave di lettura sotto il profilo della sua incidenza negativa sulla validità del matrimonio.

matrimonio scioglimento eiaculazione procreazione impotenza
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