Search results for "IAD"

NF-κB and STAT3 Inhibition as a Therapeutic Strategy in Psoriasis: In Vitro and In Vivo Effects of BTH

2013

Benzo[b]thiophen-2-yl-3-bromo-5-hydroxy-5H-furan-2-one (BTH) is a simple and interesting synthetic derivative of petrosaspongiolide M, a natural compound isolated from a sea sponge with demonstrated potent anti-inflammatory activity through inhibition of the NF-κB signaling pathway. In the present study, we report the in vitro and in vivo pharmacological effect of BTH on some parameters related to the innate and adaptive response in the pathogenesis of psoriasis. BTH inhibited the release of some of the key psoriatic cytokines such as tumor necrosis factor α, IL-8, IL-6, and CCL27 through the downregulation of NF-κB in normal human keratinocytes. Moreover, it impaired signal transducers and…

¿La ONU, irrecuperable? / 1

2005

A glimpse into the socialization of bilingual youngsters as interpreters: the case of Latino bilinguals brokering communication for their families an…

2010

Work on bilinguals who act as family interpreters, while not focused particularly on the development of translation and interpreting abilities, contributes to our understanding of life experiences of the individuals who begin to interpret early in their lives (Valdés and Angelelli 2003). With some exceptions (Harris 1977, 1978, 1980, 1992; Toury 1984, 1995) very little has been written about the lived experiences of young interpreters and/or about their socialization as family interpreters. Since most of the community interpreters of today were interpreters in their late childhood and adolescence, getting a glimpse into their lives and experiences may help researchers (and teachers of inter…

Data from: Plant – herbivorous beetle networks: molecular characterization of trophic ecology within a threatened steppic environment

2015

DNA barcoding facilitates many evolutionary and ecological studies, including the examination of the dietary diversity of herbivores. In this study, we present a survey of ecological associations between herbivorous beetles and host plants from seriously threatened European steppic grasslands. We determined host plants for the majority (65%) of steppic leaf beetles (55 species) and weevils (59) known from central Europe using two barcodes (trnL and rbcL) and two sequencing strategies (Sanger for mono/oligophagous species and Illumina for polyphagous taxa). To better understand the ecological associations between steppic beetles and their host plants, we tested the hypothesis that leaf beetl…

Modelo educativo y autogobierno valenciano 40 años de políticas educativas en la Generalitat

2022

Este artículo pretende explicar y analizar el desarrollo del modelo educativo valenciano en las últimas décadas, identificando también cuáles han sido sus resultados principales en términos de política pública. A tal fin se analizarán los principales hitos que marcan su desarrollo transitando por las diferentes etapas del autogobierno en paralelo a las grandes reformas legislativas que se han producido en España en materia de Educación. This articleaims to explain and analyze the development of the valencian educationmodel in recent decades, also identifying what its main results have been in terms of public policy. To this end, the main milestones that mark its development will be analyzed…

Oltre Omero. Aspetti storico-letterari del Ciclo epico troiano

¿Qué hacer con el Mediterráneo?

2003

Photoactivation of Drosophila melanogaster cryptochrome through sequential conformational transitions

2019

Time-resolved x-ray scattering reveals light-induced signal transduction in insect cryptochromes.

Supplementary Ultraviolet-B Radiation Induces a Rapid Reversal of the Diadinoxanthin Cycle in the Strong Light-Exposed DiatomPhaeodactylum tricornutu…

2002

AbstractA treatment of the diatom Phaeodactylum tricornutum with high light (HL) in the visible range led to the conversion of diadinoxanthin (Dd) to diatoxanthin (Dt). In a following treatment with HL plus supplementary ultraviolet (UV)-B, the Dt was rapidly epoxidized to Dd. Photosynthesis of the cells was inhibited under HL + UV-B. This is accounted for by direct damage by UV-B and damage because of the UV-B-induced reversal of the Dd cycle and the associated loss of photoprotection. The reversal of the Dd cycle by UV-B was faster in the presence of dithiothreitol, an inhibitor of the Dd de-epoxidase. Our results imply that the reversal of the Dd cycle by HL + UV-B was caused by an incre…

Interpreting in refugee contexts in Spain. An outstanding issue

2018

Interpreting in refugee contexts (IRC) has long been invisible to Western societies and Interpreting Studies. This paper aims at describing the background and features of IRC, and presents a small-scale qualitative study, whose main objectives are: exploring interpreters' perception regarding competences and role, and exploring refugees' perception regarding the quality of the interpreting service. For this purpose, a focus group and unstructured interviews were conducted in Spain. Data were analysed through comparative analysis and coding procedures. Results show interpreters' dissatisfaction with their working conditions and refugees’ experience with interpretation seems to be negative an…