Search results for "INCIDENCE"

Epidemiologie von Hirntumoren im Kindesalter

2000

The German Childhood Cancer Registry (GCCR) was established in 1980. From 1980 to 1997 4,447 CNS tumours in children below 15 years of age have been reported to the registry. From 1988 to 1997 the average annual incidence was 2.5/100,000 children. This corresponds to 19.2% of the registered diseases. Compared with incidence rates reported from other developed countries one can estimate that there is about 25% underreporting of CNS tumours in the GCCR. This is in contrast to the relatively complete ascertainment of other childhood malignancies (above 95%). Based on 3012 incident cases from 1988 to 1997 the Kaplan-Meier-estimate of 5-year-survival probability is 65% for all CNS tumours and 54…

Impact of the COVID-19 pandemic on incidence, time of diagnosis and delivery of healthcare among paediatric oncology patients in Germany in 2020: Evi…

2021

ABSTRACT Background The indirect impact of the COVID-19 pandemic on cancer care and timely diagnosis is of increasing concern. We investigated the impact of the COVID-19 pandemic on incidence, time of diagnosis and delivery of healthcare among paediatric oncology patients in Germany in 2020. Methods We analysed incident paediatric cancer cases diagnosed in 0- to 17-year olds in Germany in 2020 using data of the German Childhood Cancer Registry. Absolute numbers and age-standardised incidence rates (ASR) in 2020 were compared to the previous five years (2015–2019). Moreover, we conducted a survey with open-ended questions, gathering perceptions of the diagnostic process and healthcare delive…

Areas of research and clinical approaches to the study of liver abscess

2016

AIM To analyze the research activity on liver abscess (LA) and identify the main topic clusters in the area. METHODS We identified all documents using the medical subject heading "LA" indexed in the MEDLINE database between 2001 and 2015. We performed a descriptive bibliometric analysis, characterizing the evolution of scientific activity, the publication types of the documents, the document categories of clinical interest (case reports, clinical trials, evaluation studies, meta-analysis, observational studies, practice guidelines and validation studies) and the geographic distribution of the research. We also carried out an analysis of networks and research clusters in order to identify th…

Rare Tumors in Children and Adolescents - the STEP Working Group's Evolution to a Prospective Registry.

2021

Background Very rare tumors (VRT) in children and adolescents have such a low incidence that until recently, they have not been integrated into the clinical and scientific network of pediatric oncology. Data is very limited and consistent treatment strategies are missing. Thus, VRTs are classic orphan diseases. To counteract this problem, the Arbeitsgemeinschaft für Seltene Tumorerkrankungen in der Pädiatrie (STEP) was founded. Here we report on patient recruitment during the first 10 years. Patients Patients aged up to 18 years and not included in any other clinical trial or GPOH registry were included in this analysis. Methods Data was collected from 2008 to 2018 by means of a standardize…

STATINS FOR THE PRIMARY PREVENTION OF CARDIOVASCULAR EVENTS IN ELDERLY PATIENTS: A PICTURE FROM CLINICAL PRACTICE WITHOUT STRONG EVIDENCE FROM CLINIC…

2008

AX-PET: Concept, proof of principle and first results with phantoms

2010

AX-PET is a novel PET concept based on long crystals axially arranged and orthogonal Wavelength shifter (WLS) strips, both individually readout by Geiger-mode Avalanche Photo Diodes (G-APD). Its design was conceived in order to reduce the parallax error and simultaneously improve spatial resolution and sensitivity. The assessment of the AX-PET concept and potential was carried out through a set of measurements comprising individual module characterizations and scans in coincidence mode of point-like and extended sources. The estimated energy and spatial resolutions from point-like measurements are R FWHM =11.6% (at 511 keV) and 1.7–1.9 mm (FWHM) respectively as measured with point-like sour…

Effect of inter-crystal scatter on estimation methods for random coincidences and subsequent correction.

2008

Random coincidences can contribute substantially to the background in positron emission tomography (PET). Several estimation methods are being used for correcting them. The goal of this study was to investigate the validity of techniques for random coincidence estimation, with various low-energy thresholds (LETs). Simulated singles list-mode data of the MADPET-II small animal PET scanner were used as input. The simulations have been performed using the GATE simulation toolkit. Several sources with different geometries have been employed. We evaluated the number of random events using three methods: delayed window (DW), singles rate (SR) and time histogram fitting (TH). Since the GATE simula…

Incidence trends of colorectal cancer in the early 2000s in Italy. Figures from the IMPATTO study on colorectal cancer screening

2015

We utilised the IMPATTO study's archives to describe the 2000-2008 colorectal cancer (CRC) incidence rate trends in Italy, once screening programmes based on the faecal immunochemical test were implemented in different areas. Data on CRCs diagnosed in Italy from 2000 to 2008 in subjects aged 40-79 years were collected by 23 cancer registries. Incidence rate trends were evaluated as a whole and by macro-area (North-Centre and South-Islands), presence of a screening programme, sex, ten-year age class, anatomic site, stage at diagnosis, and pattern of diagnosis (screen-detected, non-screen-detected). The annual percent change (APC) of incidence rate trends, with 95% confidence intervals (95%CI…

Spaces of typen on partially ordered sets

1989

This paper contains a generalized approach to incidence geometry on partially ordered sets. A difference to the usual geometrical concepts is that points may have different size. Our main result states that a large class of spaces allows lattice theoretic characterizations. Especially, a generalized version of the Veblen-Young axiom of projective geometry has a lattice theoretic equivalent, called then-generation property (which is a generalization of the ‘Verbindungssatz’). Modularity and distributivity of a lattice of subspaces are reflected in the underlying space. Finally we give specializations and examples.

Elementarteiler von Inzidenzmatrizen symmetrischer Blockpläne

1986

By a study of the integral code generated by the rows of the incidence matrix and its extention the following results are obtained: Let d 1,...,d V(d 1|d 2,d 2|d 3...) be the elementary divisors of the incidence matrix of a symmetric (v,n+λ, λ) design. Then d v=(n+λ)n/g.c.d. (n, λ). Moreover, if p is a prime such that p|n, p∤λ and if x p denotes the p-part of x, then (d idv+2−i) p =n p for 2≤i≤v. For projective planes it can be shown that d 1=···=d 3n−2=1, hence $$d_{n^2 - 2n{\text{ }} + {\text{ }}5} {\text{ }} = \cdots = d_{n^2 + n} = n$$ and $$d_{n^2 - n{\text{ }} + {\text{ }}1} = (n + 1)n$$ . The paper also contains some results about elementary divisors of incidence matrices G satisfyin…