Search results for "INTERACTION"

showing 10 items of 5710 documents

Plasma Membrane Dynamics in Plant-Microbe Interactions

2017

[SDV] Life Sciences [q-bio][SDE] Environmental Sciences[SDV]Life Sciences [q-bio][SDE]Environmental Sciences[SDV.BV]Life Sciences [q-bio]/Vegetal Biology[SDV.BV] Life Sciences [q-bio]/Vegetal Biologyinteraction plante microorganismedynamique membranaire
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Molecular mechanisms underlying proteins-membrane interaction

proteins-membrane interaction alpha-lactalbumin iMSD analysisSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)
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Thin-layer chromatography of 2-methyl-4-chlorophenoxyacetic acid and its soil metabolites

1980

Abstract The thin-layer chromatography of 2-methyl-4-chlorophenoxyacetic acid, 4-chloro- o -cresol and 3-methyl-5-chlorocatechol and their pentafluorobenzyl derivatives has been studied on silica gel as adsorbent with 19 solvent systems. The best separation of the individual components occurred with toluene-benzene-acetic acid (2:2:1). Chloroform-diethyl ether-toluene (1:1:1) was suitable for the group separation of the pentafluorobenzyl derivatives.

ChromatographyChemistrySilica gelHydrophilic interaction chromatographyOrganic ChemistryGeneral MedicineCresolBiochemistryHigh-performance liquid chromatographyThin-layer chromatographyAnalytical Chemistrychemistry.chemical_compoundColumn chromatographyAdsorptionmedicineChromatography columnmedicine.drugJournal of Chromatography A
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Self-generated Drawing: A Help or Hindrance to Learning from Animation?

2017

The considerable potential of animations to aid learning about dynamic systems too often remains unfulfilled when the targeted subject matter is complex and unfamiliar. Various approaches designed to support learning from animation in such cases have met with limited success. Recent studies on learning from demanding texts indicate that educational outcomes can be improved if learners are required to self-generate drawings during their study of a text. This improvement has been attributed to the role of drawing in fostering deeper learner processing of the presented information and superior self-regulation as learning proceeds. It is possible that learner self-generation of drawings during …

MultimediaComputer science05 social sciencesPerspective (graphical)050301 educationAnimationcomputer.software_genre050105 experimental psychologySubject matterHuman–computer interactionDynamic visualization0501 psychology and cognitive sciences0503 educationcomputer
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Combination of searches for anomalous top quark couplings with 5.4 fb−1 of pp¯ collisions

2012

We present measurements of the tWb coupling form factors using information from electroweak single top quark production and from the helicity of W bosons from top quark decays in t (t) over bar events. We set upper limits on anomalous tWb coupling form factors using data collected with the DO detector at the Tevatron p (p) over bar collider corresponding to an integrated luminosity of 5.4 fb(-1).

PhysicsNuclear and High Energy PhysicsTop quarkParticle physicsLuminosity (scattering theory)010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyElectroweak interactionTevatronTop quark condensate01 natural sciencesHelicitylaw.inventionNuclear physicslaw0103 physical sciencesHigh Energy Physics::Experiment010306 general physicsColliderBosonPhysics Letters B
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Synthesis, Anti-Inflammatory Activity, and in Vitro Antitumor Effect of a Novel Class of Cyclooxygenase Inhibitors: 4-(Aryloyl)phenyl Methyl Sulfones

2010

Following our previous research on anti-inflammatory drugs (NSAIDs), we report on the design and synthesis of 4-(aryloyl)phenyl methyl sulfones. These substances were characterized for their capacity to inhibit cyclooxygenase (COX-1 and COX-2) isoenzymes. Molecular modeling studies showed that the methylsulfone group of these compounds was inserted deep in the pocket of the human COX-2 binding site, in an orientation that precludes hydrogen bonding with Arg120, Ser353, and Tyr355 through their oxygen atoms. The N-arylindole 33 was the most potent inhibitor of COX-2 and also the most selective (COX-1/COX-2 IC(50) ratio was 262). The indole derivative 33 was further tested in vivo for its ant…

Models MolecularIndolesMolecular modelCell SurvivalStereochemistrymedicine.drug_classAntineoplastic AgentsAnti-inflammatoryStructure-Activity RelationshipIn vivoCell Line TumorDrug DiscoverymedicineAnimalsHumansCyclooxygenase InhibitorsSulfonesBinding siteIC50Cell ProliferationIndole testCyclooxygenase 2 InhibitorsbiologyChemistryStereoisomerismSettore CHIM/08 - Chimica FarmaceuticaIn vitroRats4-(Aryloyl)phenyl methyl sulfones anti-inflammatory activity antitumor effect COX-1/COX-2 selectivityCyclooxygenase 1biology.proteinThermodynamicsMolecular MedicineCyclooxygenaseDrug Screening Assays AntitumorHydrophobic and Hydrophilic InteractionsJournal of Medicinal Chemistry
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Interaction between Longitudinal Shear and Transverse Bending in Prestressed Concrete Box Girders

2017

In box girder bridges, the quantity and distribution of reinforcement to be put in concrete elements of sections can be evaluated only by considering the deformation of the cross section in addition to the longitudinal analysis of the static scheme, establishing the entire state of stress of box sections. This leads to a need to evaluate the interaction between internal forces obtained by the global analysis and the ones obtained by the local analysis of the cross sections. The frame effect implies the elastic deformation of slabs and webs, whereas eccentrically applied loads lead to cross-section distortion with the loss of the box shape. Hence, the reinforcement is strongly influenced by …

EngineeringTransverse bendingBox girders bridges0211 other engineering and technologies020101 civil engineering02 engineering and technologyPlasticity0201 civil engineeringlaw.inventionPrestressed concreteInteraction domainslawGirder021105 building & constructionReinforcementCivil and Structural Engineeringbusiness.industryBox girders bridges; Interaction domains; Prestressed concrete; Shear; Thin-walled section; Transverse bending; Web; Civil and Structural Engineering; Building and ConstructionShearBox girderBuilding and ConstructionStructural engineeringWebSettore ICAR/09 - Tecnica Delle CostruzioniThin-walled sectionStress resultantsBending momentPrestressed concreteDeformation (engineering)businessJournal of Bridge Engineering
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Sosiomateriaalinen näkökulma vuorovaikutukseen muuttuvissa työtiloissa

2022

Työelämään ja organisaatioihin ovat viime vuosina vaikuttaneet monet eri muutokset. Yksi voimakkaimmista muutoksista koskee sitä, missä töitä tehdään eli työnteon tiloja. Tutkimuksissa on tarkasteltu muun muassa tilojen roolia ihmisten välisen vuorovaikutuksen edistämisessä, työntekijöiden oppimisen tukemisessa sekä inklusiivisuuden ja monimuotoisuuden vahvistamisessa. Viime aikoina huomiota on kiinnitetty erityisesti siihen, miten tilat vaikuttavat ihmisten toimijuuteen eli kykyyn ja mahdollisuuksiin toimia tai vaikuttaa erilaisiin työhön liittyviin tilanteisiin. Tässä puheenvuorossa keskityn siihen, miten tilojen ja ihmistoimijuuden välistä suhdetta voidaan tutkia niin kutsutusta sosiomat…

intra-actionvuorovaikutustyötilatworkspaceinteractionyhteismuotoutuminentoimijuusorganizationsosiaalinen vuorovaikutusorganisaatiotutkimussociomaterialitytyötilaorganisaatiososiomateriaalisuusPharmacology (medical)Keynote-puheenvuoromateriaalisuusPrologi
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Determination of enrichment factors for modified RNA in MeRIP experiments

2019

In the growing field of RNA modification, precipitation techniques using antibodies play an important role. However, little is known about their specificities and protocols are missing to assess their effectiveness. Here we present a method to assess enrichment factors after MeRIP-type pulldown experiments, here exemplified with a commercial antibody against N6-methyladenosine (m6A). Testing different pulldown and elution conditions, we measure enrichment factors of 4-5 using m6A-containing mRNAs against an unmodified control of identical sequence. Both types of mRNA carry 32P labels at different nucleotides, allowing their relative quantification in a mixture after digestion to nucleotides…

Models MolecularAdenosineAbsolute quantificationMethylationProtein Structure SecondaryGeneral Biochemistry Genetics and Molecular BiologyViral Proteins03 medical and health sciencesAdenosine TriphosphateRNA modificationEscherichia coliHumansImmunoprecipitationProtein Interaction Domains and MotifsNucleotideRNA MessengerMolecular Biology030304 developmental biologychemistry.chemical_classification0303 health sciencesMessenger RNACell-Free SystemChemistryElution030302 biochemistry & molecular biologyRNADNA-Directed RNA PolymerasesBiochemistryImmunoglobulin GIsotope LabelingChromatography Thin LayerPhosphorus RadioisotopesProtein BindingMethods
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Solution and solid-state studies on the halide binding affinity of perfluorophenyl-armed uranyl–salophen receptors enhanced by anion–π Interactions

2016

The enhancement of the binding between halide anions and a Lewis acidic uranyl-salophen receptor has been achieved by the introduction of pendant electron- deficient arene units into the receptor skeleton. The association and the occurrence of the elusive anion-p interaction with halide anions (as tetrabutylammonium salts) have been demonstrated in solution and in the solid state, providing unambiguous evidence on the interplay of the concerted interactions responsible for the anion binding.

anion–π interactions; halides; host–guest systems; lewis acid–base interactions; uranyl–salophen; chemistry (all)Solid-stateHalide010402 general chemistry01 natural sciencesCatalysisIonUranyl salophenPolymer chemistryOrganic chemistryReceptorAnion bindingta116Uranyl-salphenlewis acid–base interactionsanion–π interactionsuranyl–salophen010405 organic chemistryChemistryOrganic Chemistryhost–guest systemsGeneral Chemistryinteractions0104 chemical sciencesuranyl-salophen receptorshalideschemistry (all)halide recognitionanions
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