Search results for "INTERACTION"
showing 10 items of 5710 documents
Transcatheter Heart Valve Implantation in Bicuspid Patients with Self-Expanding Device
2021
Bicuspid aortic valve (BAV) patients are conventionally not treated by transcathether aortic valve implantation (TAVI) because of anatomic constraint with unfavorable outcome. Patient-specific numerical simulation of TAVI in BAV may predict important clinical insights to assess the conformability of the transcathether heart valves (THV) implanted on the aortic root of members of this challenging patient population. We aimed to develop a computational approach and virtually simulate TAVI in a group of n.6 stenotic BAV patients using the self-expanding Evolut Pro THV. Specifically, the structural mechanics were evaluated by a finite-element model to estimate the deformed THV configuration in …
Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules
2020
Immunosuppression with glucocorticoids is a common treatment for autoimmune liver diseases and after liver transplant, which is however associated with severe side-effects. Targeted delivery of glucocorticoids to inflammatory cells, e.g. liver macrophages and Kupffer cells, is a promising approach for minimizing side effects. Herein, we prepare core–shell silica nanocapsules (SiO2 NCs) via a sol–gel process confined in nanodroplets for targeted delivery of dexamethasone (DXM) for liver immunosuppressive therapy. DXM with concentrations up to 100 mg mL−1 in olive oil are encapsulated while encapsulation efficiency remains over 95% after 15 days. Internalization of NCs by non-parenchymal muri…
Response of bird predators for female wood tiger moth chemical defences
2018
Multiple behavioural responses of blue tit predators to the defence fluids of wood tiger moth (Arctia plantaginis) females that were either food deprived or fed ad libitum during development.
Noroviral P-Particles as an In Vitro Model to Assess the Interactions of Noroviruses with Probiotics
2014
Noroviruses (NoVs) are the main etiologic agents of acute epidemic gastroenteritis and probiotic bacteria have been reported to exert a positive effect on viral diarrhea. The protruding (P) domain from NoVs VP1 capsid protein has the ability to assemble into the so-called P-particles, which retain the binding ability to host receptors. We purified the P-domains from NoVs genotypes GI.1 and GII.4 as 6X(His)-tagged proteins and determined that, similar to native domains, they were structured into P-particles that were functional in the recognition of the specific glycoconjugated receptors, as established by surface plasmon resonance experiments. We showed that several lactic acid bacteria (pr…
Relationships Between Organizational Justice and Burnout at the Work-Unit Level.
2005
Relationships between organizational justice and well-being are traditionally investigated at the individual level. This article extends previous efforts by testing such relationships at the work-unit level. Three corridors of influence were examined. First, the level (work units’ average scores) of justice is related to the level of burnout. Second, justice climate strength (level of agreement among work-unit members) moderates the predictability of the level of burnout. Third, justice strength is related to burnout strength. The authors interviewed 324 contact employees from 108 work units in 59 service organizations. Findings showed the predominance of interactional justice over distribu…
Langage et Apprentissage en Interaction pour des Assistants Numériques Autonomes - Une Approche Développementale
2021
The rapid development of digital assistants (DA) opens the way to new modes of interaction. Some DA allows users to personalise the way they respond to queries, in particular by teaching them new procedures. This work proposes to use machine learning methods to enrich the linguistic and procedural generalisation capabilities of these systems. The challenge is to reconcile rapid learning skills, necessary for a smooth user experience, with a sufficiently large generalisation capacity. Though this is a natural human ability, it remains out-of-reach for artificial systems and this leads us to approach these issues from the perspective of developmental Artificial Intelligence. This work is thus…
Children’s Engagement with Mathematics in Kindergarten Mediated by the Use of Digital Tools
2013
The purpose of this chapter is to study children’s engagement with mathematics in kindergarten mediated by digital tools within the context of interactive whiteboard (IWB). Our study reports from a research project aiming at analysing in what ways digital tools may nurture children’s appropriation processes relative to mathematics. In adopting a sociocultural perspective on learning and development, observations together with video recordings have been analysed. Our study shows that the children make sense of the digital tools and are able to apply the tools purposefully due to the interaction with an adult within the zone of proximal development (ZPD). The children externalise their reason…
Educar
2015
El presente artículo describe una experiencia de formación en alternancia en un contexto de educación superior; en concreto, a partir de la iniciativa desarrollada por Florida Universitaria, centro adscrito a la Universidad de Valencia. La formación en alternancia implica alternar el aprendizaje entre períodos desarrollados en el centro educativo y momentos desarrollados en el contexto laboral. El objetivo del presente trabajo es identificar una iniciativa que, de forma empírica, muestre cómo estos periodos impactan en el aprendizaje de competencias de los estudiantes. La metodología que se ha aplicado en la experiencia de formación en alternancia se basa en el aprendizaje basado en problem…
Anàlisi de les interaccions en fòrums de discussió a través del Campus Andalús Virtual
2012
En el presente trabajo se expone un análisis de las interacciones que se producen en una experiencia formativa a través del Campus Andaluz Virtual. Para ello, se han analizado un total de 284 cuestionarios de evaluación, así como 1538 mensajes que se han intercambiado en los foros de discusión destinados al trabajo colaborativo para resolver tareas académicas. Los resultados nos indican cuáles son los factores más importantes de una comunidad de aprendizaje y cuáles han sido las intervenciones más frecuentes en la realización de tareas de aprendizaje cooperativo en red.
Energetic coupling between plastids and mitochondria drives CO2 assimilation in diatoms.
2015
International audience; Diatoms are one of the most ecologically successful classes of photosynthetic marine eukaryotes in the contemporary oceans. Over the past 30 million years, they have helped to moderate Earth's climate by absorbing carbon dioxide from the atmosphere, sequestering it via the biological carbon pump and ultimately burying organic carbon in the lithosphere. The proportion of planetary primary production by diatoms in the modern oceans is roughly equivalent to that of terrestrial rainforests. In photosynthesis, the efficient conversion of carbon dioxide into organic matter requires a tight control of the ATP/NADPH ratio which, in other photosynthetic organisms, relies prin…