Search results for "IPR"

ANTIPROLIFERATIVE ACTIVITY OF CITRUS JUICES AND HPLC EVALUATION OF THEIR FLAVONOID COMPOSITION

2007

The antiproliferative activity of fresh fruit juices extracted from Citrus sinensis (cv. Washington Navel and cv. Sanguinello), C. deliciosa cv. Avana, C. clementina cv. Nules, C. aurantium subsp. myrtifolia , was evaluated against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. All the juices tested showed antiproliferative activity. Moreover, the pattern of the main flavanone compounds in the juices has been determined by HPLC analysis.

La validación del clima de justicia y de la justicia entre compañeros en un entorno real de trabajo

2016

Abstract In this study we tested the validity of justice climate and peer justice, measured as second-order constructs, in a real work setting. First, we investigated the appropriateness of aggregating first-order facets of justice climate and peer justice to work-unit level of analysis. Second, we examined the construct validity of justice climate and peer justice as two different factor structures. Third, we tested the hierarchical structure of justice climate and peer justice as second-order factors. Finally, we examined the predictive validity of second-order factors justice climate and peer justice within a nomological network composed of reciprocity with the supervisor and reciprocity…

Psychotropic Drugs in the Management of Chronic Pain Syndromes

1993

Psychotropic drugs have been integrated into the management of chronic pain syndromes for more than 30 years. Numerous open and controlled studies have taken place evaluating especially the antinociceptive efficacy of antidepressive drugs. This survey comprises the results of clinical reports, open clinical studies, placebo-controlled studies, and comparative studies of different substances. It will be shown that antidepressants are by far the best evaluated psychopharmacological substances, showing superiority against placebo in 70% of a total of 67 placebo-controlled studies. The synopsis of controlled comparison studies of different antidepressants tends to demonstrate a superiority of c…

2013

The amyloid-β42 (Aβ42) peptide plays a crucial role in the pathogenesis of Alzheimer’s disease (AD), the most common neurodegenerative disorder affecting the elderly. Over the past years, several approaches and compounds developed for the treatment of AD have failed in clinical studies, likely in part due to their low penetration of the blood–brain barrier (BBB). Since nanotechnology-based strategies offer new possibilities for the delivery of drugs to the brain, this technique is studied intensively for the treatment of AD and other neurological disorders. The Aβ42 lowering drug flurbiprofen was embedded in polylactide (PLA) nanoparticles by emulsification-diffusion technique and their pot…

1. Recognition And Social Ontology: An Introduction

2011

One of Hegel's big ideas is that creatures with a self-conception are the subjects of developmental processes that exhibit a distinctive structure. Call a creature 'essentially self-conscious' if what it is for itself, its self- conception, is an essential element of what it is in itself. How something that is essentially self-conscious appears to itself is part of what it really is. This chapter shows how the tripartite account of erotic awareness can be used in a natural way to build a notion of recognition that satisfies these twin philosophical constraints on the interpretation of Hegel's notion of self-consciousness in terms of recognition. Doing so it clarifies the nature of the trans…

2-Cinnamamido, 2-(3-phenylpropiolamido), and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity, and mechanism of action

2013

Abstract Several new benzamides 4a–q were synthesized by stirring in pyridine the acid chlorides 3a–q with the appropriate anthranilamide derivatives 2a–g. Some of the synthesized compounds were evaluated for their in vitro antiproliferative activity against a panel of 5 human cell lines (K562 human chronic myelogenous leukemia cells, MCF-7 breast cancer cells, HTC-116 and HT26 colon cancer cells and NCI H460 non-small cell lung cancer cells).

Parabolic Subgroups of Artin Groups

1997

Abstract Let ( A , Σ) be an Artin system. For X  ⊆ Σ, we denote by A X the subgroup of A generated by X . Such a group is called a parabolic subgroup of A . We reprove Van der Lek's theorem: “a parabolic subgroup of an Artin group is an Artin group.” We give an algorithm which decides whether two parabolic subgroups of an Artin group are conjugate. Let A be a finite type Artin group, and let A X be a parabolic subgroup with connected associated Coxeter graph. The quasi-centralizer of A X in A is the set of β in A such that β X β −1  =  X . We prove that the commensurator of A X in A is equal to the normalizer of A X in A , and that this group is generated by A X and the quasi-centralizer of…

On the consequences of the standard polynomial

1998

The purpose of this paper is to shed some light on the polynomial identities of low degree for the n × n matrix algebra over a field of characteristic 0.Our main result is that we have found all the consequences of degree n + 2 of the standard polynomial have calculated the S n+2-character of the T-ideal generated by this polynomial.

On the lattice of J-subnormal subgroups

1992

Gaussian Groups and Garside Groups, Two Generalisations of Artin Groups

1999

It is known that a number of algebraic properties of the braid groups extend to arbitrary finite Coxeter-type Artin groups. Here we show how to extend the results to more general groups that we call Garside groups. Define a Gaussian monoid to be a finitely generated cancellative monoid where the expressions of a given element have bounded lengths, and where left and right lowest common multiples exist. A Garside monoid is a Gaussian monoid in which the left and right lowest common multiples satisfy an additional symmetry condition. A Gaussian group is the group of fractions of a Gaussian monoid, and a Garside group is the group of fractions of a Garside monoid. Braid groups and, more genera…