Search results for "ISMU"
showing 10 items of 685 documents
Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair
2015
Reactive oxygen and nitrogen species (e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. In addition, classical regulation of gene expression or activity, including gene transcription to RNA followed by translation to the protein level, by transcription factors (e.g. NF-κB, HIF-1α) and mRNA binding proteins (e.g. GAPDH, HuR) is subject to redox regulation. This review will give an update of recent discoveries in this field, and specifically highlight the impact of reactive oxygen and nitrogen species on DNA repair systems that contribute to genomic stability. Emphasis will be placed …
A radiometric and petrographic interpretation of discrepancies on uranium content in samples collected at Alte Madonie Mounts region (Sicily, Italy)
2013
Abstract The main goal of this work is to evaluate a correlation between anomalous Uranium (U) content and petrographic features of some soil and rock samples collected at Alte Madonie Mounts region (North-central Sicily, Italy). A total of 41 samples of selected soils and rocks were collected, powdered, dried and sealed in “Marinelli” beakers for 20 days before the measurement to ensure that radioactive equilibrium between 226 Ra and 214 Bi was reached. Gamma-ray spectrometric analysis was used to quantify radioactivity concentrations. Mineralogical and chemical features of the samples were determined by X-ray Fluorescence (XRF), X-ray Diffractometry (XRD), Attenuated Total Reflection-Four…
La voce dei sommersi. Destino della musica europea negli anni del nazismo
2002
Il saggio traccia un quadro della politica culturale nazista nell'ambito della musica, con particolare riferimento alla mostra Entartete Musik ("Musica degenerata", 1938) e ai compositori attivi nel ghetto di Theresienstadt. L'ultimo capitolo è dedicato ai percorsi biografici e artistici di Viktor Ullmann e alla genesi, alla drammaturgia e ai caratteri musicali dell'opera in un atto "Der Kaiser von Atlantis" (L'Imperatore di Atlantide, 1943-44).
IMPROVEMENT IN REDOX HOMEOSTASIS AFTER CYTOREDUCTIVE SURGERY IN COLORECTAL ADENOCARCINOMA
2021
Colorectal cancer (CRC) as one the most common cancer type is associated with oxidative stress. Surgery is the only curative modality for early-stage CRC. The aim of this study was to evaluate the oxidative damage biomarkers as well as enzymatic and nonenzymatic antioxidants in patients with CRC before and after tumor resection and in healthy controls. 60 patients with stage I/II colorectal adenocarcinoma and 43 healthy controls were recruited in this study. We measured plasma levels of oxidative damage biomarkers, including advanced oxidation protein products (AOPP), advanced glycation end products (AGEs), malondialdehyde (MDA), and oxidized low-density lipoprotein (ox-LDL) at baseline and…
Slāņainu grafēns/Bi2Se3 struktūru sintēze
2016
Darbā uz elektroķīmiski pulētām vara pamatnēm tika sintezēts ķīmisko tvaiku nogulsnēts grafēns. Optimizēta grafēna pārnešanas procedūra, veicot grafēna pārnešanas procesā izmantotā poli(metilmetakrilāta) šķīdināšanu etiķskābes šķīdumos. Tika pārbaudīta grafēna kvalitāte pirms un pēc pārnešanas uz nevadošam pamatnēm izmantojot Ramana spektroskopiju, elektrovadītspējas mērījumiem un apskati skenējošā elektronu mikroskopā. Darbā ir izstrādāta horizontālu un dažādos leņķos orientētu bismuta selenīda nanostruktūru uz grafēna virsmas sintēzes metode. Ir noteikts iegūto slāņaino grafēns/Bi2Se3 struktūru termoelektriskais un fotoelektriskais efekts.
Dopētu un nedopētu bismuta selenīda nanolaminātu veidošana un raksturošana
2019
Dopētu un nedopētu bismuta selenīdu nanolaminātu veidošana un raksturošana. Britāla L., zinātniskie vadītāji Dr. phys., vadošā pētniece Andžāne J., Dr. chem., asoc. prof. Erts D. Bakalaura darbs, -- lappuses, -- attēli, -- tabulas, -- literatūras avoti, -- pielikumi. Latviešu valodā. Šajā pētījumā tiek izstrādāta metode ar alvu dopētu un nedopētu Bi2Se3 ultraplānu kārtiņu, ar biezumu 10 nm, sintēzei uz grafēna virsmas. Secīgi sintezējot šādi strukturētus bismuta selenīda slāņus, uz grafēna pamatnes tiek izveidots nanolamināts, kurš sastāv no dopētām un nedopētām ultraplānām bismuta selenīda kārtiņām. Noteiktas šo nanolaminātu termoelektriskās īpašības un tos ietekmējošie faktori.
Il contributo dell'architettura per la ridefinizione dell'Accademia e di Brera
2013
The contribution of Architecture to the redefinition of the Brera Academy. A comparison of the sorry state of the republican education and its places with international architecture that exemplifies a different attitude towards culture such as the Openbare Bibliotheek in Amsterdam, evidencing a serious Italian short fall.The author proposes an alternative project starting with the cancellation of all the projects and competitions so far proposed in an uncoordinated manner, from the Grande Brera project to the unacceptable transfer of the Academy. Furthermore, he proposes an international com- petition for the whole Brera complex, the Pinacoteca, Academy and Observatory, that would enable st…
Genetic manipulation of longevity-related genes as a tool to regulate yeast life span and metabolite production during winemaking
2013
Abstract Background Yeast viability and vitality are essential for different industrial processes where the yeast Saccharomyces cerevisiae is used as a biotechnological tool. Therefore, the decline of yeast biological functions during aging may compromise their successful biotechnological use. Life span is controlled by a variety of molecular mechanisms, many of which are connected to stress tolerance and genomic stability, although the metabolic status of a cell has proven a main factor affecting its longevity. Acetic acid and ethanol accumulation shorten chronological life span (CLS), while glycerol extends it. Results Different age-related gene classes have been modified by deletion or o…
Fabrication of Bismuth Absorber Arrays for NTD-Ge Hard X-ray Microcalorimeters
2020
The high-spectral-resolution detection of hard X-rays (E > 20 keV) is a challenging and nearly unexplored area in space astrophysics. Traditionally hard X-ray detectors present moderate spectral resolutions, although few tens of eV one could open new frontiers in the study of nuclear processes and high-temperature plasma dynamics in energetic processes. This can be achieved by using cryogenic microcalorimeters. Within a research activity aimed at developing arrays of neutron transmutation-doped germanium (NTD-Ge) microcalorimeters for the high-spectral-resolution detection (about 50 eV@60 keV) of hard X-rays (20 keV < E<100 keV), we developed an electroplating process to fabricate …
Museo - köydenvetoa tiedon ja elämyksien välillä : pohdintaa Suomen kulttuurihistoriallisten museoiden merkityksistä Suomen kansallismuseon ja Helsin…
2015
Tämän pro gradu -tutkielman tarkoituksena on selvittää Suomen kulttuurihistoriallisten museoiden merkityksiä nykypäivänä pyrkimällä myös hieman ennustamaan tulevaisuudennäkymiä Suomen kansallismuseon ja Helsingin kaupunginmuseon museokävijöiden ja museoammattilaisten antamien näkökulmien kautta. Pro gradu -tutkielmani on esiselvitys laajemmille tutkimuksille sekä empiirisen aineiston hankinnan kokeilu, joiden pohjalta on mahdollista tulevaisuudessa tehdä kattavat tutkimukset Suomen kulttuurihistoriallisten museoiden merkityksistä. Tutkielmani otosmuseoiden avulla halutaan vastata kysymyksiin: 1. Minkälaisia merkityksiä Suomen kulttuurihistoriallisille museoille annetaan nykypäivänä, ja mink…