Search results for "ISMU"
showing 10 items of 685 documents
A step forward in the development of superoxide dismutase mimetic nanozymes: the effect of the charge of the surface on antioxidant activity
2019
Two binucleating hezaaza macrocycles containing a pyridinol spacer have been prepared and characterised. Protonation studies indicate the deprotonation of the phenol group at relatively low pH values with the concomitant occurrence of a keto-enolic equilibrium. These ligands readily form binuclear Cu2+ and Zn2+ complexes as denoted by potentiometric and spectroscopic studies. The binding of the metals yields to the ready deprotonation of the phenol with the stabilisation of the keto form that results in complexes of greater stabilities than the analogous ones containing pyridine as spacer instead of pyridine. Mixed Cu2+–Zn2+-complexes were also detected in aqueous solutions containing equim…
Synergistic Anticancer Therapy by Ovalbumin Encapsulation-Enabled Tandem Reactive Oxygen Species Generation
2020
Abstract The anticancer efficacy of photodynamic therapy (PDT) is limited due to the hypoxic features of solid tumors. We report synergistic PDT/chemotherapy with integrated tandem Fenton reactions mediated by ovalbumin encapsulation for improved in vivo anticancer therapy via an enhanced reactive oxygen species (ROS) generation mechanism. O2 .− produced by the PDT is converted to H2O2 by superoxide dismutase, followed by the transformation of H2O2 to the highly toxic .OH via Fenton reactions by Fe2+ originating from the dissolution of co‐loaded Fe3O4 nanoparticles. The PDT process further facilitates the endosomal/lysosomal escape of the active agents and enhances their intracellular deliv…
Globins and hypoxia adaptation in the goldfish, Carassius auratus
2008
Goldfish (Carassius auratus) may survive in aquatic environments with low oxygen partial pressures. We investigated the contribution of respiratory proteins to hypoxia tolerance in C. auratus. We determined the complete coding sequence of hemoglobin α and β and myoglobin, as well as partial cDNAs from neuroglobin and cytoglobin. Like the common carp (Cyprinus carpio), C. auratus possesses two paralogous myoglobin genes that duplicated within the cyprinid lineage. Myoglobin is also expressed in nonmuscle tissues. By means of quantitative real-time RT-PCR, we determined the changes in mRNA levels of hemoglobin, myoglobin, neuroglobin and cytoglobin in goldfish exposed to prolonged hypoxia (48…
Frazeoloģijas jautājumu izpratnes padziļināšana latviešu valodas stundās 10.klasē
2018
Diplomdarba „Frazeoloģijas jautājumu izpratnes padziļināšana latviešu valodas stundās 10. klasē” mērķis ir izstrādāt un aprobēt mūsdienīgu mācību materiālu kopu frazeoloģijas jautājumu izpratnes padziļināšanai latviešu valodas stundās 10. klasē, lai veicinātu skolēnu ieinteresētību frazeoloģijas jautājumu apguvē. Diplomdarbam ir ievads, divas nodaļas un apakšnodaļas, secinājumi un 15 pielikumi. Pirmajā nodaļā ir apzinātas un apkopotas valodnieku atziņas par frazeoloģismiem, to lomu valodā. Otrajā nodaļā aprakstīta diplomdarba autores sagatavošanās darbam klasē, raksturotas pētāmās klases vecumposma īpatnības, apkopots latviešu valodas un literatūras didaktiķu un skolotāju viedoklis par fraz…
Sosiomateriaalinen näkökulma vuorovaikutukseen muuttuvissa työtiloissa
2022
Työelämään ja organisaatioihin ovat viime vuosina vaikuttaneet monet eri muutokset. Yksi voimakkaimmista muutoksista koskee sitä, missä töitä tehdään eli työnteon tiloja. Tutkimuksissa on tarkasteltu muun muassa tilojen roolia ihmisten välisen vuorovaikutuksen edistämisessä, työntekijöiden oppimisen tukemisessa sekä inklusiivisuuden ja monimuotoisuuden vahvistamisessa. Viime aikoina huomiota on kiinnitetty erityisesti siihen, miten tilat vaikuttavat ihmisten toimijuuteen eli kykyyn ja mahdollisuuksiin toimia tai vaikuttaa erilaisiin työhön liittyviin tilanteisiin. Tässä puheenvuorossa keskityn siihen, miten tilojen ja ihmistoimijuuden välistä suhdetta voidaan tutkia niin kutsutusta sosiomat…
Detailed spectroscopy of 195Bi
2017
An experiment focused on the study of shape coexistence and new high-spin structures in 195 Bi has been performed. The nucleus is in a transitional region of the bismuth isotope chain. A large number of new states have been found, resulting in a significant extension of the previously known level scheme. Several new collective structures have been identified. A strongly coupled rotational band built upon the 13 / 2 + isomeric state was extended up to I π = ( 49 / 2 + ) and an energy of 5706 keV. The I π = 31 / 2 + member of the π i 13 / 2 band was also found to feed a new long-lived isomeric state with an excitation energy of 2616 keV and a spin and parity of I π = 29 / 2 + . The half-life …
Detailed spectroscopy of the neutron-deficient bismuth isotopes ¹⁹³,¹⁹⁵Bi
2015
Two experiments aiming to study the shape coexistence and competing structures in 193Bi and 195Bi isotopes have been performed at the Accelerator laboratory of the University of Jyv askyl a, Finland (JYFL). Many new states have been found, hugely extending the previously known level schemes for both isotopes. The i13=2 bands were extended up to I = 45/2+ in both the 193;195Bi isotopes. In case of 193Bi, the I = 31/2+ member of the i13=2 band was found to de-excite also to a long-lived isomeric state. This link determines the energy of the isomeric state to be 2350(1) keV and suggests a spin and parity of 29/2+. The half-life of the isomeric state was measured to be 85(3) s. A level structur…
Etnisyyden rakentuminen kahden saamelaismuseon perusnäyttelyissä
2015
This study examines the construction of ethnicity in the permanent exhibitions of two museums: Siida, the National Museum of the Finnish Sámi and the Nature Centre of Metsähallitus, and Ájtte, the Swedish Mountain and Sámi Museum. The study is motivated by three research questions: What kind of ethnic categories and boundaries do the exhibitions create? How is Sámi ethnicity defined by displaying cultural features? How do the exhibitions depict relationships between the Sámi and other ethnicities, governmental power, the ‘Sámi area’, and nature? The exhibitions are examined in the context of the contemporary public discussion about Sámi ethnicity; the study aims to explain how the two museu…
Reporting in Conflict Zones in Pakistan: Risks and Challenges for Fixers
2020
As a backbone of reporting in war and conflicts, fixers offer essential assistance to the foreign correspondent in conflict zones, also in Pakistan. With valuable local knowledge and contacts, fixers can arrange travel to secure entry of foreign correspondents into conflict zones in addition to securing interviews with otherwise unattainable figures, while offering reliable translation services. Pakistani media, despite being one of the largest and most developed in South Asia, remains under the strict control of powerful military establishment and government, while seeming to mirror the overarching government sentiment with a distinct lack of research-based news. Challenging this state of …
A Relational Approach to How Media Engage With Their Audiences in Social Media
2022
People are increasingly turning to social media for their news and for sharing and discussing news with others. Simultaneously, media organizations are becoming platform-dependent and posting short forms of their news on their social media sites in the hope that audiences will not only consume this news but also comment on and share it. This article joins other media and journalism studies exploring this phenomenon through a relational approach to media audiences to better understand how media organizations, particularly newspapers, are cultivating relationships with audiences via social media. Drawing on public relations theory about organization–public relationships, the article examines …